The impact of cigarette dependence severity on disease outcomes and depression in ankylosing spondylitis

Year 2018, Volume: 4 Issue: 4, 374 - 380, 04.10.2018

Seyhan Dülger , İlknur Aykurt Karlıbel , Tekin Yıldız , Lale Altan Özlem Şengören Dikiş , Meliha Kasapoğlu Aksoy

https://doi.org/10.18621/eurj.336935

Abstract

Introduction: Ankylosing spondylitis (AS) is a chronic systemic
inflammatory disease. Smoking plays a role in AS pathogenesis and causes
difficulties in its treatment. The aim of this study is to investigate the
association of disease activity, functional status, spinal mobility,
depression, chest expansion, pain, fatigue, quality of life, respiratory
function with cigarette dependence severity in patients with AS.

Methods:
The study included 71 patients diagnosed as AS. Patients were evaluated on
questionnaires and examination scales specific to assessment of AS. The results
were compared using the SPSS-23 software.

Results: Out of the total 71
patients, 40 (56.3%) were smokers, 31 (43.7%) were non-smokers. There were no significant
differences between the smokers and the non-smokers with respect to the median
values in Bath Ankylosing Spondylitis Disease Activity Index, Bath Ankylosing
Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Functional
Index, Ankylosing Spondylitis Quality of Life questionnaire, Short Form 36
(SF-36), chest expansion, the fingertip-to-floor test and Beck Depression
Inventory (p > 0.05). However, there were significant differences when
comparing the median scores on BASMI (p
= 0.036), SF-36 physical role strength (p
= 0.004) and the chest expansion (p =
0.015) of the smoker patients placed in the three Fagerström Test for Nicotine
Dependence (FTND) subgrouping.

Conclusion: AS patients with
smoking have elevated FTND scores and worse values for test of disease activity
and quality of life.

Keywords

Smoking, ankylosing spondylitis, life quality

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