The effect of Enterobius vermicularis infection (oxyuriasis) on eosinophil and IgE levels in allergic rhinitis

Year 2018, Volume: 4 Issue: 4, 399 - 404, 04.10.2018

Fevzi Solmaz , Oğuzhan Dikici Davut Akduman , Mehmet Haksever , İsmail Necati Hakyemez Muhammed Yanılmaz

https://doi.org/10.18621/eurj.344495

Cited By: 1

Abstract

Objective:
Elevated levels of serum IgE and eosinophilia are the indicators of atopy and
intestinal parasitic infections. We evaluated the effect of Enterobius vermicularis infection
(enterobiasis) on blood eosinophil count and IgE levels in allergic rhinitis.

Methods:
A total of 110 patients diagnosed with allergic rhinitis (with symptoms of
rhinorrhea, itchy nose and nasal congestion) consisting of 41 (37.27%) males
and 69 (62.73%) females were examined. Forty-one (37.27%) patients with
enterobiasis were selected as the study group. The remaining 69 (62.73%) patients
accepted as the control group.

Results: In the study group the mean
serum total IgE level and mean serum eosinophil count were 393.10 ± 159.83 IU/mL
and 0.56 ± 0.04 10³/mL, respectively. In the control group the mean
serum total IgE level and mean serum eosinophil count were 236.91 ± 63.55 IU/mL
and 0.37 ± 0.12 10³/mL, respectively. The difference between the two
groups was statistically significant for serum total IgE levels (p < 0.05) but not for serum
eosinophil count (p > 0.05). The
correlation coefficients between serum total IgE level and eosinophil count
were statistically insignificant (p >
0.05).

Conclusions: More comprehensive and long-term
placebo-controlled studies should be performed in order to find the answer to
the question of whether helminth infections play a role in allergic disease. 

Keywords

Enterobius vermicularis infection; allergic rhinitis; serum IgE level; serum eosinophil count.

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