The
patients with end-stage renal disease have an increased risk of atherosclerosis
and the probability of cardiovascular diseases. Due to the use of
immunosuppressive agents, the patients having renal graft carry an additional
risk of atherosclerosis or endocarditis. A 67-year-old male patient with a
history of renal transplantation was referred to our hospital with a severe
chest pain and dyspnea. After diagnosing severe ischemic coronary artery
disease by coronary angiography, the patient underwent a successful operation
of a single vessel coronary artery bypass grafting (CABG) in beating heart. Up
to 20% of post-renal transplantation mortality is attributed to cardiovascular
diseases. Graft rejection, the need of hemodialysis, perioperative infection
are some of the major complications for renal transplant patients undergoing
CABG surgery. Off-pump CABG (OPCABG) surgery is a less invasive technique in
comparison with CABG with cardiopulmonary bypass (CPB), and protects the
patient from negative effects of CPB such as complement system activation,
inflammatory mediator secretion, thrombocytopenia, clotting disorders. We
recommend to prefer OPCABG and have preoperative prophylaxis in order to avoid
both perioperative infection and renal graft rejection in renal transplant
patients undergoing CABG surgery.
Coronary artery bypass grafting renal transplant cardiopulmonary bypass beating heart immunosuppressive treatment
Primary Language | English |
---|---|
Subjects | Health Care Administration |
Journal Section | Case Reports |
Authors | |
Publication Date | March 4, 2019 |
Submission Date | January 30, 2018 |
Acceptance Date | March 11, 2018 |
Published in Issue | Year 2019 Volume: 5 Issue: 2 |