Increased mean platelet volume in patients with vestibular migraine

Year 2020, Volume: 6 Issue: 2, 99 - 104, 04.03.2020

Mehmet Emin Çavuş , Talip Talha Tanyeli Fatih Alper Akcan , Ömer Bayır , Didem Gökkurt

https://doi.org/10.18621/eurj.463535

Abstract

Objectives:
The purpose of this study was to investigate relation
between mean platelet volume, platelet distribution width, platelet-to-lymphocyte
ratio, neutrophil-to-lymphocyte ratio and vestibular migraine.

Methods: This study was planned in prospective
manner and conducted
in Ankara Polatlı State Hospital between April 2017 and May 2018. Thirty patients
diagnosed with vestibular migraine and thirty healthy, age and sex-matched
subjects were enrolled to the study. Mean platelet volume, platelet
distribution width, platelet count, neutrophil count and lymphocyte count in
blood samples were measured.

Results: The mean age of the patients with vestibular
migraine was 39.90 ± 7.16 and the study group consisted
of 11 males and 19 females. The mean platelet volume and platelet
distribution width values in patients with vestibular
migraine were significantly higher than the control group
(p < 0.001). There were no difference
on mean neutrophil/lymphocyte ratio and platelet/lymphocyte ratio values between
patient group and control group.

Conclusions: We found a positive relation of
increased levels of mean
platelet volume and platelet distribution width with vestibular
migraine. Higher mean platelet volume is associated with atherosclerosis and thromboembolism.
Vascular pathologies are blamed for both headache syndromes like migraine and vertiginous
syndromes. This theory supports our study but pathophysiological mechanism is
not clear. 

Keywords

Hematologic parameters, mean platelet volume, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, vestibular migraine

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