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Is Less Surgical Treatment Possible in the Treatment of Degenerative Spine Diseases? Four-Year Follow-up Results of Foraminal Epidural and Facet Joint Injection Treatments

Year 2023, , 627 - 632, 25.10.2023
https://doi.org/10.54005/geneltip.1374425

Abstract

Aim
The study aims to examine the long-term outcomes of foraminal epidural injection and facet joint injection therapies in patients over the age of 60 who have been recommended for surgical intervention for degenerative spinal diseases but have declined surgical treatment due to comorbidities, anesthesia risks, and surgical risks.
Methods
Between 2018-2019, patients over the age of 60 diagnosed with Degenerative Spinal Disease who declined the recommended surgical treatment and underwent foraminal epidural and facet joint injection therapies were retrospectively evaluated. Patients were assessed using the visual pain scale and MacNab classifications during an average follow-up period of 57.14 (45-68) months. Inclusion criteria for the study included patients being continuously followed up and treated at the same center, regularly attending check-up examinations, and not having emergency surgical indications.
Results
The study included 35 patients with an average follow-up period of 57.14 months. Patients were treated with either facet joint or foraminal epidural injections in a single session based on their symptoms and complaints. The most striking result of our study is that the visual pain scale and MacNab classification outcomes after spinal injection therapy can be used as indicators for long-term results.
Conclusion
Sharing the outcomes of commonly practiced spinal injection therapies in the literature more frequently will provide guidance for the treatment planning of challenging conditions, especially like degenerative spinal disease.

References

  • McPhee B, Swanson CE. The surgical management of degenerative lumbar scoliosis: posterior instrumentation alone versus two stage surgery. Bull Hosp Joint Dis. 1998; 57(1):16–22.
  • Grubb SA, Lipscomb HJ, Coonrad RV. Degenerative adult onset scoliosis. Spine 1988;13(3):241–45.
  • Hanley1 EN Jr. The indication for lumbar spinal fusion with and without instrumentation. Spine 1995; 20 (24):143–53
  • Benner B, Ehni G. Degenerative lumbar scoliosis. Spine 1979; 4(6):548–52.
  • Daffner SD, Vaccaro AR. Adult degenerative lumbar scoliosis. Am J Orthop 2003; 32(2):77–82.
  • Teichtahl AJ, Urquhart DM, Wang Y, Wluka AE, Wijethilake P, O'Sullivan R et al. Fat infiltration of paraspinal muscles is associated with low back pain, disability, and structural abnormalities in community-based adults. Spine J. 2015; 15, 1593–601.
  • Kim WJ, Shin HM, Lee JS, Song DG, Lee JW, Chang SH, et al. Sarcopenia and Back Muscle Degeneration as Risk Factors for Degenerative Adult Spinal Deformity with Sagittal Imbalance and Degenerative Spinal Disease: A Comparative Study. World Neurosurg. 2021, 148, 547–55.
  • Hiyama A, Katoh H, Sakai D, Tanaka M, Sato M, Watanabe M. The correlation analysis between sagittal alignment and cross-sectional area of paraspinal muscle in patients with lumbar spinal stenosis and degenerative spondylolisthesis. BMC Musculoskelet. Disord. 2019; 20, 352.
  • Ploumis A, Transfledt EE, Denis F. Degenerative lumbar scoliosis associated with spinal stenosis. Spine J 2007; 7 :428–36.
  • Tribus CB. Degenerative lumbar scoliosis: evaluation and management. J Am Acad Orthop Surg 2003; 11:174–83.
  • Berven SH, Deviren V, Mitchell B, Wahba G, Hu SS, Bradford DS. Operative management of degenerative scoliosis: an evidence-based approach to surgical strategies based on linical and radiographic outcomes. Neurosurg Clin N Am 2007; 18:261–72.
  • Banno T, Yamato Y, Hasegawa T, Kobayashi S, Togawa D, Oe S, et al. Assessment of the Cross-Sectional Areas of the Psoas Major and Multifidus Muscles in Patients with Adult Spinal Deformity: A Case-Control Study. Clin. Spine Surg. 2017; 30, 968–73.
  • Jermy JE, Copley PC, Poon MTC. Demetriades, A.K. Does pre-operative multifidus morphology on MRI predict clinical outcomes in adults following surgical treatment for degenerative lumbar spine disease? A systematic review. Eur. Spine J. 2020; 29, 1318–27.
  • Zhu W, Wang W, Kong C, Wang Y, Pan F, Lu S. Lumbar Muscle Fat Content Has More Correlations with Living Quality than Sagittal Vertical Axis in Elderly Patients with Degenerative Lumbar Disorders. Clin. Interv. Aging 2020;15,1717–26.
  • Kim JB, Chang MC. Spinal cord injury by direct damage during trigger point injection: a case report. J Int Med Res. 2021;49.
  • Mather LE, Chang DH. Cardiotoxicity with modern local anaesthetics: is there a safer choice? Drugs. 2001; 61:333–42.
  • Zink W, Graf BM. The toxicity of local anesthetics: the place of ropiv‑acaine and levobupivacaine. Curr Opin Anaesthesiol. 2008; 21:645–50.
  • Shimba A, Ikuta K. Control of immunity by glucocorticoids in health and disease. Semin Immunopathol. 2020; 42:669–80.
  • Feeley IH, Healy EF, Noel J, Kiely PJ, Murphy TM. Particulate and non-particulate steroids in spinal epidurals: a systematic review and meta-analysis. Eur Spine J. 2017; 26:336–44.
  • Derby R, Lee SH, Date ES, Lee JH, Leeet CH. Size and aggregation of corticosteroids used for epidural injections. Pain Med. 2008; 9:227–34.
  • Engel A, King W, MacVicar J. The efectiveness and risks of fuoroscopi‑cally guided cervical transforaminal injections of steroids: a systematic review with comprehensive analysis of the published data. Pain Med. 2014; 15:386–402.
  • Manchikanti1 L, Candido KD, Singh V, Gharibo CG, Boswell MV, Benyaminet RM, et al. Epidural steroid warning con‑troversy still dogging FDA. Pain Physician. 2014; 17:451–74
  • Kamp JPM, Bartlett J, Fahmy A, To K, Hossain R, Akula M . CT-guided vs. fuoroscopically guided transforaminal epidural steroid injections for lumbar radiculopa‑thy: a comparison of efcacy, safety and cost. Arch Orthop Trauma Surg 2022.

Dejeneratif Omurga Hastaliklarinin Tedavisinde Daha Az Müdahale Mümkün Mü? Foraminal Epidural ve Faset Eklem Enjeksiyon Terapilerimizin Dört Yillik Takip Sonuçları

Year 2023, , 627 - 632, 25.10.2023
https://doi.org/10.54005/geneltip.1374425

Abstract

Amaç
Bu çalışma, dejeneratif omurga hastalığı nedeniyle cerrahi müdahale önerilen ancak ek hastalıklar, anestezi riskleri ve cerrahi riskler nedeniyle cerrahi tedaviyi reddeden 60 yaş üzeri hastalarda foraminal epidural enjeksiyon ve faset eklem enjeksiyon tedavilerinin uzun dönem sonuçlarını incelemeyi amaçlamaktadır.
Yöntemler
2018-2019 yılları arasında, Dejeneratif Omurga Hastalığı tanısı almış, önerilen cerrahi tedaviyi reddedip foraminal epidural ve faset eklem enjeksiyon tedavilerine başvuran 60 yaş üzeri hastalar retrospektif olarak değerlendirildi. Hastalar, ortalama 57.14 (45-68) aylık bir takip süresince görsel ağrı ölçeği ve MacNab sınıflamaları kullanılarak değerlendirildi. Çalışmaya dahil edilme kriterleri arasında hastaların sürekli olarak aynı merkezde takip edilmesi, düzenli olarak kontrole gelmesi ve acil cerrahi göstergelerinin bulunmaması yer aldı.
Sonuçlar
Çalışmaya, ortalama takip süresi 57, 14 ay olan 35 hasta dahil edildi. Hastalar, semptomlarına ve şikayetlerine bağlı olarak tek seansta ya faset eklem ya da foraminal epidural enjeksiyonları ile tedavi edildi. Çalışmamızın en çarpıcı sonucu, omurga enjeksiyon tedavisinden sonra görsel ağrı ölçeği ve MacNab sınıflama sonuçlarının uzun dönem sonuçları için göstergeler olarak kullanılabileceğidir.
Sonuç
Literatürde sıkça uygulanan omurga enjeksiyon tedavilerinin sonuçlarını daha sık paylaşmak, özellikle dejeneratif omurga hastalığı gibi zorlu durumların tedavi planlaması için rehberlik sağlayacaktır.

References

  • McPhee B, Swanson CE. The surgical management of degenerative lumbar scoliosis: posterior instrumentation alone versus two stage surgery. Bull Hosp Joint Dis. 1998; 57(1):16–22.
  • Grubb SA, Lipscomb HJ, Coonrad RV. Degenerative adult onset scoliosis. Spine 1988;13(3):241–45.
  • Hanley1 EN Jr. The indication for lumbar spinal fusion with and without instrumentation. Spine 1995; 20 (24):143–53
  • Benner B, Ehni G. Degenerative lumbar scoliosis. Spine 1979; 4(6):548–52.
  • Daffner SD, Vaccaro AR. Adult degenerative lumbar scoliosis. Am J Orthop 2003; 32(2):77–82.
  • Teichtahl AJ, Urquhart DM, Wang Y, Wluka AE, Wijethilake P, O'Sullivan R et al. Fat infiltration of paraspinal muscles is associated with low back pain, disability, and structural abnormalities in community-based adults. Spine J. 2015; 15, 1593–601.
  • Kim WJ, Shin HM, Lee JS, Song DG, Lee JW, Chang SH, et al. Sarcopenia and Back Muscle Degeneration as Risk Factors for Degenerative Adult Spinal Deformity with Sagittal Imbalance and Degenerative Spinal Disease: A Comparative Study. World Neurosurg. 2021, 148, 547–55.
  • Hiyama A, Katoh H, Sakai D, Tanaka M, Sato M, Watanabe M. The correlation analysis between sagittal alignment and cross-sectional area of paraspinal muscle in patients with lumbar spinal stenosis and degenerative spondylolisthesis. BMC Musculoskelet. Disord. 2019; 20, 352.
  • Ploumis A, Transfledt EE, Denis F. Degenerative lumbar scoliosis associated with spinal stenosis. Spine J 2007; 7 :428–36.
  • Tribus CB. Degenerative lumbar scoliosis: evaluation and management. J Am Acad Orthop Surg 2003; 11:174–83.
  • Berven SH, Deviren V, Mitchell B, Wahba G, Hu SS, Bradford DS. Operative management of degenerative scoliosis: an evidence-based approach to surgical strategies based on linical and radiographic outcomes. Neurosurg Clin N Am 2007; 18:261–72.
  • Banno T, Yamato Y, Hasegawa T, Kobayashi S, Togawa D, Oe S, et al. Assessment of the Cross-Sectional Areas of the Psoas Major and Multifidus Muscles in Patients with Adult Spinal Deformity: A Case-Control Study. Clin. Spine Surg. 2017; 30, 968–73.
  • Jermy JE, Copley PC, Poon MTC. Demetriades, A.K. Does pre-operative multifidus morphology on MRI predict clinical outcomes in adults following surgical treatment for degenerative lumbar spine disease? A systematic review. Eur. Spine J. 2020; 29, 1318–27.
  • Zhu W, Wang W, Kong C, Wang Y, Pan F, Lu S. Lumbar Muscle Fat Content Has More Correlations with Living Quality than Sagittal Vertical Axis in Elderly Patients with Degenerative Lumbar Disorders. Clin. Interv. Aging 2020;15,1717–26.
  • Kim JB, Chang MC. Spinal cord injury by direct damage during trigger point injection: a case report. J Int Med Res. 2021;49.
  • Mather LE, Chang DH. Cardiotoxicity with modern local anaesthetics: is there a safer choice? Drugs. 2001; 61:333–42.
  • Zink W, Graf BM. The toxicity of local anesthetics: the place of ropiv‑acaine and levobupivacaine. Curr Opin Anaesthesiol. 2008; 21:645–50.
  • Shimba A, Ikuta K. Control of immunity by glucocorticoids in health and disease. Semin Immunopathol. 2020; 42:669–80.
  • Feeley IH, Healy EF, Noel J, Kiely PJ, Murphy TM. Particulate and non-particulate steroids in spinal epidurals: a systematic review and meta-analysis. Eur Spine J. 2017; 26:336–44.
  • Derby R, Lee SH, Date ES, Lee JH, Leeet CH. Size and aggregation of corticosteroids used for epidural injections. Pain Med. 2008; 9:227–34.
  • Engel A, King W, MacVicar J. The efectiveness and risks of fuoroscopi‑cally guided cervical transforaminal injections of steroids: a systematic review with comprehensive analysis of the published data. Pain Med. 2014; 15:386–402.
  • Manchikanti1 L, Candido KD, Singh V, Gharibo CG, Boswell MV, Benyaminet RM, et al. Epidural steroid warning con‑troversy still dogging FDA. Pain Physician. 2014; 17:451–74
  • Kamp JPM, Bartlett J, Fahmy A, To K, Hossain R, Akula M . CT-guided vs. fuoroscopically guided transforaminal epidural steroid injections for lumbar radiculopa‑thy: a comparison of efcacy, safety and cost. Arch Orthop Trauma Surg 2022.
There are 23 citations in total.

Details

Primary Language English
Subjects Pain, Geriatrics and Gerontology, Clinical Sciences (Other)
Journal Section Original Article
Authors

Derya Karaoğlu Gündoğdu 0000-0003-2345-8818

Yunus Kaçar 0000-0002-9475-2718

Early Pub Date October 23, 2023
Publication Date October 25, 2023
Submission Date October 11, 2023
Acceptance Date October 16, 2023
Published in Issue Year 2023

Cite

Vancouver Karaoğlu Gündoğdu D, Kaçar Y. Is Less Surgical Treatment Possible in the Treatment of Degenerative Spine Diseases? Four-Year Follow-up Results of Foraminal Epidural and Facet Joint Injection Treatments. Genel Tıp Derg. 2023;33(5):627-32.