Relationship Between Dementia and Comorbid Diseases

Year 2018, Volume: 1 Issue: 2, 32 - 39, 29.10.2018

Saadet Koç Okudur , Özge Dokuzlar , Pınar Soysal , Ahmet Turan Işık

Abstract

Aim: Dementia
is an increasingly frequent health problem worldwide. It is known that comorbid
disease prevelance is high in dementia patients. Dementia can challenge the
management of comorbid diseases and the ability of patients to manage chronic
conditions. The aim of this study is to assess the relationship between
dementia and comorbidity.

Methods: 2264 patients aged 60 years and over were included
in the study. Patients were divided into 2 groups who have dementia and
no dementia. Chronic disease
information, socio-demographic data, drug numbers were evaluated
retrospectively from patient follow-up files. The results obtained were
compared among the patient groups.

Results: The
mean age of 1767 non-demented patients was 74.36 ± 8.5, and the mean age of 497
demented patients was 78.06 ± 8.48. Hypertension was the most common chronic
disease in both groups of patients. The total number of comorbid diseases in the
non-demented group was 3.06, and in demented group was 2.69. The Charlson
Comorbidity Index was significantly higher in the demented patient group (p
<0.001).

Conclusion: It is known that comorbid diseases such as
diabetes, hypertension and hypercholesterolemia play role in dementia risk, but
these findings suggest that vascular risk factors in etiopathogenesis of
dementia might not be forefront and other risk factors may take part of disease
development.

Keywords

elderly, dementia, comorbidity, chronic disease

Demans ve Komorbid Hastalıklarla İlişkisi

Abstract

Amaç: Demans,
dünya genelinde sıklığı giderek artan bir sağlık problemidir. Demans
hastalarında komorbid hastalık sıklığının yüksek olduğu bilinmektedir. Demans
varlığı, komorbid hastalıkların yönetimini ve hastaların kronik durumu yönetme
becerisini zorlaştırabilir. Bu çalışmanın amacı, demans ve komorbidite
ilişkisini değerlendirmektir.

Metod: Çalışmaya,
60
yaş ve üstü, 2264 hasta
alındı. Hastalar demansı olan ve olmayan olmak üzere 2 gruba ayrıldı. Kronik hastalık bilgileri,
sosyo-demografik verileri, ilaç sayılarına dair veriler hasta takip dosyalarından elde edilerek retrospektif
olarak değerlendirildi. Elde edilen sonuçlar hasta grupları arasında
karşılaştırıldı.

Bulgular:
Çalışmaya
dahil edilen demansı olmayan 1767 hastanın yaş ortalaması 74,36 ± 8,5, demansı
olan 497 hastanın yaş ortalaması ise 78.06 ± 8,48 idi. Her iki hasta grubunda
en sık görülen kronik hastalık hipertansiyondu. Demansı olan hastalarda ortalama komorbid hastalık
sayısı ise 2,69, demansı olmayanlarda ise 3,06 idi. Demansı olan hastalarda
Charlson Komorbidite
İndeksi anlamlı olarak daha yüksek bulundu (p<0.001).

Sonuç:
Bu bulgular, demans gelişiminde diyabet,
hipertansiyon, hiperkolesterolemi gibi komorbid hastalıkların risk faktörü
olarak rol oynadığı bilinse de etiyopatogenezde vasküler risk faktörlerinin ön
planda yer almadığı, hastalık gelişiminde başka faktörlerin de yer aldığını
düşündürmektedir.

Keywords

yaşlı, demans, komorbidite, kronik hastalık

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