Abstract
Drinking water potentially affects a variety of diseases, and their relationship to environmental risk factors is an emerging area that still needs to be clarified. Studies have reported that aluminum and fluoride, elements naturally found in water, have an adverse effect on human health with increasing concentration in drinking water, which is affected by environmental aspects. High aluminum levels in drinking water can cause dementia. Many studies have found an association between the amount of aluminum in drinking water and an increased risk of Alzheimer's. The absorption of aluminum and fluoride is thought to have a positive relationship and together have greater bioavailability. The health effects of aluminum and fluoride can vary depending on the source of the water, the duration of exposure, and the body's detox system. It is crucial to control the content of drinking water in order for humans' vital activities to be healthy. In this review, the general properties and interactions of aluminum and fluoride, which are important for human health, will be discussed. Considering the important toxic effects of these chemicals, the relationship between diseases and health problems will be evaluated.