Kemiğin dev hücreli tümörü taklit eden primer hiperparatiroidizme bağlı brown tümörü

Year 2018, Volume: 8 Issue: 2, 171 - 173, 16.05.2018

Ayşe Kevser Demir , Faruk Kutlutürk , Serdar Savaş Gül Özge Gümüşay

https://doi.org/10.16899/gopctd.370895

Cited By: 1

Abstract

Primer
hiperparatiroidizm (PHP) parathormon seviyelerinin yüksekliği ile karakterize
endokrin bir hastalıktır. Hiperparatiroidizm
komplikasyonlarından biri olan Brown tümörü, osteoklastik aktivite sonucu
ortaya çıkar ve iskelet sisteminde lezyonlar, patolojik kırık ve ağrıya sebep
olabilir. Brown tümörü hem
histopatolojik hem de radyolojik incelemelerde primer kemik tümörü,
anevrizmal kemik kisti veya kemiğin dev hücreli tümörü ile karışabilir. Bu sunumda
metastatik kemik tümöründen şüphelenilen ancak primer hiperparatroidi tanısı
alan 50 yaşında bayan hastanın sunumu yapılmaktadır. Brown tümörleri benign karakterli lezyonlardır ama malign
kemik hastalıklarını taklit edebilirler. Hastalığın ayırıcı tanısında
klinik, histopatolojik ve radyolojik bulguların birlikte değerlendirilmelidir.

Keywords

Hiperparatiroidizm, Brown tümörü

Brown tumor caused by primary hyperparathyroidism mimicking giant cell tumor of bone

Abstract

Primary hyperparathyroidism (PHP) is an endocrine
disorder characterized by the elevation of parathormone levels. Brown tumor,
one of the complications of hyperparathyroidism, is the result of osteoclastic
activity resulting in lesions, pathological fractures and pain in the skeletal
system. Brown tumor can be confused with primary bone tumor, aneurysmal bone
cyst or giant cell tumor of bone in both histopathological and radiological
examinations. In this presentation, a 50-year-old female patient with a
suspicion of metastatic bone tumor but diagnosed with primary
hyperparathyroidism is presented. Brown tumors are benign lesions, but they can
mimic malign bone diseases. Clinical, histopathologic and radiological findings
should be evaluated together in differential diagnosis of the disease.

Keywords

Hyperparathyroidism, Brown tumor

References

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