Çocukluk Çağı Testis Tümörleri

Year 2018, Volume: 8 Issue: 1, 34 - 36, 17.04.2018

Ünal Bıçakçı , Dilek Demirel , Sertaç Hancıoğlu Ender Arıtürk , Ferit Bernay

https://doi.org/10.16899/gopctd.332439

Cited By: 1

Abstract

Amaç

Testis tümörleri çocukluk
çağında nadir görülmektedir. Bu çalışmada kliniğimizde testis tümörü nedeni ile
ameliyat edilen olguların değerlendirilmesi amaçlandı.

Hastalar
ve yöntem

2006- 2016 tarihleri
arasında testiste kitle nedeniyle ameliyat edilen 20 hasta yaş, başvuru
bulguları, taraf, metastaz varlığı, uygulanan cerrahi, histopatolojik
değerlendirme sonuçları, ameliyat öncesi AFP ve βHCG düzeyleri açısından geriye
dönük olarak incelendi.

Bulgular

Yaşları 0,4- 17,5 yıl
arasında (ortalama 8,8 yıl) olan 20 hasta çalışmaya alındı. Tamamı ağrısız
skrotal şişlikle başvurdu. Ameliyat öncesi 9 (% 45) hastanın (5 teratom ve 4
endodermal sinüs tümörü) AFP ve 4 (% 20) hastanın (3 teratom ve 1 endodermal
sinüs tümörü) βHCG değeri yüksekti. Hastaların 5’inde tanı esnasında metastaz
vardı (2 akciğer ve 3 retroperitoneal lenf nodu). Hastaların 8’ine (% 40)
frozen biyopsi sonrası orşiektomi, 9’una (% 45) orşiektomi, 1’ine (% 5) frozen biyopsi
sonrası testis koruyucu cerrahi, neoplastik infiltrasyon olan 2 (% 10)  hastaya ise doku tanısı için sadece testis
biyopsisi uygulandı. Histopatolojik incelemede 13 (% 65) hastada germ hücreli
tümör bulundu. Bunlar; 4 (% 20) endodermal sinüs tümörü, 5 (% 25)  mikst germ hücreli tümör, 3 (% 15) teratom, 1
(% 5) seminom)’du. 4 (% 20) hastada neoplastik infiltrasyon,  2 (% 10) hastada  paratestiküler rabdomyosarkom, 1 (% 5)
hastada ise malign mezenkimal tümör görüldü. Hastaların 15’i (% 75) kemoterapi,
2’si (% 10,5) radyoterapi aldı. Hastalardan 5’inde (% 25) metastaz görüldü.
Takiplerinde neoplastik infiltrasyonu olan 2 (% 10,5) hasta exitus oldu.

 

Sonuç

Çocukluk çağı testis
malignitelerinde uygun hastalarda testis koruyucu cerrahi denenmelidir. Frozen biyopsi
cerrahi yöntemin belirlenmesinde yardımcıdır. 

Keywords

Çocukluk çağı testis tümörleri, frozen biyopsi, testis koruyucu cerrahi

Childhood Testicular Tumors

Abstract

Objective

Testicular tumors are rare in childhood In this study,
it was aimed evaluate our patients with testicular tumor.

Patients and methods

Twenty patients had been evaluated between 2006- 2016
in terms of age, presenting symptoms, side, presence of metastasis, surgical
intervention, histopathological evaluation results, preoperative AFP and βhcg
levels.

Results

Twenty patients were between 0.4
and 17.5 years old (median 8.8 years). 
Preoperative AFP values ​​were high in 9 (45%) patients (5 teratom and 4
endodermal sinus tumor) and βHCG values were high in 4 (20%) patients (3
teratom and 1 endodermal sinus tumor). At diagnosis, 5 patients had metastasis
( 2 luns and 3 retroperitoneal lymh nodes). 8 (40%) patients underwent
orchiectomy after frozen biopsy, 9 (45%) patients underwent orchiectomy, 1 (5%)
patient underwent testis sparing surgery after frozen biopsy. Histopathological
examination revealed that there was germ cell tumor in 13 (65%) patients including
endodermal sinus tumor in 5 (25%) patients, mixed germ cell tumor in 4 (20%)
patients, teratoma in 3 (15%) patients, seminoma in 1 patient), neoplastic infiltration
in 4 (20%) patients, paratesticular rhabdomyosarcoma in 2 (10%) patients and malign
mesenchymal tumor in 1 (5%) patient. 14 (70%) patients received chemotherapy
and 2 (10.5%) patients received radiotherapy. 
Metastases developed in 3 (15.7%) of the patients.  Two (10.5%) patients with neoplastic
infiltration were exitus.

 

Conclusion

In childhood testicular malignancies, testis sparing
surgery should be tried in appropriate patients.  Frozen biopsy is helpful in determining
surgical method.

Keywords

Childhood testicular tumors, frozen biopsy

References

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