Gastroesophageal Reflux Disease in Children

Year 2014, Volume: 4 Issue: 3, 175 - 184, 18.01.2015

Ceyda Tuna Kırsaçlıoğlu , Tülin Köksal

https://doi.org/10.16899/ctd.64946

Abstract

Gastroesophageal reflux disease is defined as a clinical condition characterized by symptoms and findings which is caused as a result of involuntary passage of the gastric contents into the esophagus. It is a multifactorial disorder. Patients can admit with symptoms of gastrointestinal or extra gastrointestinal system, like respiratory system. Diagnosis and treatment approaches are still controversial.

 

Keywords

Gastroesophageal reflux disease; childhood; treatment

Çocuklarda Gastroözofagiyal Reflü Hastalığı

Abstract

Gastroözofagiyal reflü hastalığı (GÖRH), mide içeriğinin özofagusa istemsiz geçişi sonucu oluşan belirti ve bulgularla karakterize klinik bir durum olarak tanımlanır. Multifaktoryel bir bozukluktur. Hastalar gastrointestinal ya da solunum sistemi gibi gastrointestinal olmayan bulgularla başvurabilirler.  Tanı ve tedavi yaklaşımları halen tartışmalıdır.

 

 

Keywords

Gastroözofagiyal reflü hastalığı; çocukluk çağı; tedavi

References

• Vandenplas Y, Rudolph CD, Lorenzo CD, Hassall E, Liptak G et al. Pediatric gastroesophageal reflux cliinical practice guidelines: Joint recommendations of the North American Society for pediatric gastroenterology, hepatology and nutrition (NASPGHAN) and European Society for pediatric gastroenterology, hepatology and nutrition. J Pediatr Gastroenterol Hepatol 2009; 49: 498-547.
• Vakil N. Disease definition, clinical manifestations, epidemiology and natural history of GERD. Best Practice Res Clin Gastroenterol 2010: 24; 759-64.
• Oranstein SR. Khan S. Gastroesophageal reflux. Walker WA, Kleinman RE, Sherman PM, Scneider BL, Sandersen IR editors. Pediatric gastrointestinal Disease Pathophysiology, Diagnosis Management. 4th ed. Ontario, BC Decker Inc, 2004: 384-99.
• Sherman P Hassall E, Fagundes Neto U et al. Global evidence based consensus on the definition of gastroesophageal reflux disease in the pediatric population. Am J Gastroenterol 2009; 04:1278-95.
• Park KY, Chang SH. Gastro-Esophageal reflux disease in healty older children and adolescents. Pediatr Gastroenterol Hepatol Nutr 2012; 15: 220-8.
• Lightdale JR, Gremse DA. Gastroesophageal reflux: Management guidance for the pediatrician. Pediatrics; 2013; 131: e 1684-95.
• Condino AA, Sondheimer J, Pan Z, ve ark. Evaluation of gastroesophagealreflux in pediatric patients with asthma using impedance-pH monitoring. J Pediatr 2006;149:216–9.
• Poddar U. Diagnosis and management of gastroesophageal reflux disease (GERD): Indian Perspective. Indian Pediatr 2013; 16: 119-126.
• Holbrook JT, Wise RA,Gold BD, Blake K, Brown ED, ve ark.. Lansoprazole for children with poorly controlled asthma. JAMA.2012;307:373-81.
• Wales PW, Diamond IR, Dutta S, ve ark. Fundoplication and gastrostomy versus image-guided gastrojejunal tube for enteral feeding in neurologically impaired children with gastroesophageal reflux. J Pediatr Surg 2002;37:407–12.
• Qadeer MA, Phillips CO, Lopez AR, ve ark. Proton pump inhibitor therapy for suspected GERD-related chronic laryngitis: a metaanalysis of randomized controlled trials. Am J Gastroenterol 2006;101:2646–54.
• Williams RB, Szczesniak MM, Maclean JC, et al. Predictors of outcome in an open label, therapeutic trial of high-dose omeprazole in laryngitis. Am J Gastroenterol 2004;99:777–85.
• El-Serag HB, Gilger M, Kuebeler M, et al. Extraesophageal associations of gastroesophageal reflux disease in children without neurologic defects. Gastroenterology 2001;121:1294–9.
• Picos A, Chisnoıu A, Dumitrascu D. Dental erosion in patients with gastroesophageal reflux disease. Adv Clin Exp Med 2013; 22: 303-7.
• Cerimagic D, Ivkic G, Bilic E. Neuroanatomical basis of Sandifer’s syndrome: a new vagal reflex? Med Hypotheses 2008;70: 957–61.
• Omari TI, Barnett CP, Benninga MA, ve ark. Mechanisms of gastro-oesophageal reflux in preterm and term infants with reflux disease. Gut. 2002;51:475–9.
• Hegar B, Vandenplas Y. Gastroesophageal reflux: natural evolution, diagnsotic approach and treatment. Turkish J Pediatr. 2013; 55: 1-7.
• Liu XL, Wong KKY. Gastroesophageal reflux disease in children. Hong Kong Med J 2012; 18: 421-8.
• Mousen HH, Rosen R, Woodley FW, Orsi M, Armas D et al. Esophageal impedans monitoring for gastroesophageal reflux. J Pediatr Hepatol Nutr 2011; 52: 129-139.
• Loots CM, Benninga MA, Davidson GP, Omarı T. Addition of pH impedance monitoring to standart pH monitoring increases the yield of symtom association analysis in infants and children with gastroesophageal reflux. J Pediatr 2009; 154: 248-52.
• Van Wijk MP, Benninga MA, Omari, TI. Role of multichannel intraluminal impedance technique in infants and children. J Pediatr Gastroenterol Nutr 2008; 48: 2-12.
• Khoshoo V, Ross G, Brown S, ve ark. Smaller volume, thickened formulas in the management of gastroesophageal reflux in thriving infants. J Pediatr Gastroenterol Nutr 2000;31:554–6.
• Corvaglia L, Martini S, Aceti A, Arcuri S, Rossini R. Faldella G. Nonpharmacological management of gastroesophageal reflux in preterm infants. Biomed Res Int 2013; 2013: 141267.
• Corvaglia L, Rotatori R, Ferlini M, Aceti A, Ancora G, Faldella G. The effect of body positioning on gastroesophageal reflux in premature infants: evaluation by combined impedance and pH monitoring. J Pediatr. 2007;151(6):591–596.
• Zhao C-X, Yue X-H, Lu H, Xue X-D. Effects of nonnutritive sucking on gastric emptying and gastroesophageal reflux in premature infants. Chinese J Pediatr. 2004;42(10):772–776
• Guimareaes EV, Marguet C, Camargos PAM. Treatment of gastroesophageal reflux disease. J Pediatr 2006; 82: s133-45.
• Vander Pol R, Smits MJ, Van Wijk M, Omari T, Tabbers MM, Benninga MA. Efficacy of proton pomp inhibitors in children with gastroesophageal reflux disease: A systematic Review. Pediatrics 2011; 127: 925-35.
• Pritchard DS, Baber N, Stephenson BT. Should domperidon be used fort he treatment of gastroesophageal reflux in children? Systemic review of randomized controlled trials in children aged 1 month to 11 years old. Br J Clin Pharmacol 2005; 59: 725-9.
• Corvaglia L, Aceti A, Mariani E, De Giorgi M, Capretti MG, Faldella G. The efficacy of sodium alginate (Gaviscon) for the treatment of gastro-oesophageal reflux in preterm infants. Aliment Pharmacol Ther. 2011 33:466-70.
• Illueca M, Wernersson B, Henderson C, Lundborg P. Maintenance treatment with proton pump inhibitors for reflux esophagitis in pediatric patients.: a systematic literature analysis. J Pediatr Gastroenterol Nutr. 2010; 51:733-40.