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Year 2016, Volume: 29 Issue: 2, 303 - 307, 20.06.2016

Elif Loğoğlu , Elif Aynacı Koyuncu Münteha Nur Sonuç Karaboğa Nursen Sarı

Abstract

References

  • References
  • R. Eglof, P. Piotr, B. Bogumil, B. Franz, Curr Org. Chem. 13 (2009) 241-249.
  • G. Ellis, L. Chang, B. Cogionis, D. Daneman, Clin. Chem. 43 (1997) 2437-2439.
  • A.R. Fakhari, A.R. Khorrami, H. Naeimi, Talanta 66 (2005) 813-817.
  • U. Abram, R. Alberto, J Braz Chem Soc 17 (2006) 1486-1500.
  • M. Gharagozlou, D.M. Boghaei, Spectrochim Acta A 71 (2008) 1617-1622.
  • R.M. Wang, C.J. Hao, Y.P. Wang, S.B. Li, J Mol Catal A-Chem 147 (1999) 173-178.
  • W.K. Jung, H.C. Koo, K.W. Kim, S. Shin, S.H. Y.H Kim, Park Appl Environ Microb 74 (2008) 2171-2178.
  • A.P. Mishra, M. Soni Metal-Based Drugs 2008 ID 875410 (2008) 1-7.
  • S.A. Manley, S. Byrns, A.W. Lyon, P. Brown, J. Gailer, J Biol Inorg Chem 14 (2009) 61-74.
  • S.J. Lippard, J.M. Berg, Principles of Bioinorganic Chemistry, University Science Books, Mill Valley, CA, USA, (1994) p 64-276.
  • A.A. Abd El-Raady, T. Nakajima, Ozone-Scı Eng 27 (2005) 11-18.
  • S. Kobayashi, K. Ueda, T. Komano, Agric Biol Chem 54 (1990) 69-76.
  • D. Nartop, P. Gürkan, N. Sarı, S. Çete,. J Coord Chem 61 (2008) 3516-3524.
  • N. Sarı, J Macromol Sci A 43 (2006) 1609-1618.
  • N. Sari, P. Gürkan, S. Arslan, Trans Metal Chem 28 (2003) 468-474.
  • J.R. Anacona, I. Osorio, Transit Metal Chem 33 (2008) 517-521.
  • I. Şakiyan, Trans Metal Chem 32 (2007) 131-135.
  • I. Kaya, A. Bilici, M. Gul, Polym advan technol 19 (2008) 1154-1163.
  • N. Sarı, P. Gürkan, S. Çete, I. Şakiyan, Russ J Coord Chem 32 (2006) 511-517.
  • N. Sarı, P. Gürkan, Trans Metal Chem 28 (2003) 687-693.
  • N.S. Agar, J.R. Mahoney, J.W. Eaton, Biochem-Pharmacol 41 (1991) 985-993.
  • H. Zhang, C. Andrekopoulos, J. Joseph, J. Crow, B. Kalyanaraman, Free Radical Bio Med 36 (2004) 1355-1365.
  • S.I. Liochev, I. Fridovich, J Biol Chem 277 (2002) 34674-34678.
  • Z.H. Zhao, Y. Sakagami, T. Osaka, Can. J. Microbiol 44 (1998) 441-447.
  • S.P. Denyer, G.S.A.B Stewart, Int Biodeter Biodegr 41 (1998) 261-268.

Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes

Year 2016, Volume: 29 Issue: 2, 303 - 307, 20.06.2016

Elif Loğoğlu , Elif Aynacı Koyuncu Münteha Nur Sonuç Karaboğa Nursen Sarı

Abstract

This study aimed to investigate of the antimicrobial activities of some amino acid-Schiff bases complexes as theoretical aspects. Co(II), Cu(II) and Ni(II) complexes of N,N'-(1,4-phenylenedimetiliden)bis DL-Alanine and N,N'-(1,4-phenylendimetiliden)bis DL-Glisine were been prepared and characterized. The antibacterial and antifungal activities were measured by Disc diffusion and MIC method against gram-positive bacteria i.e. Psydomamonas aeruginosa ATCC 29212, Bacillus subtilis RSKK 244, Bacillus megaterium(clinical isolate), gramnegative bacteria Micrococcus Luteus NRRLB and as fungus Candida albicans. The antibiogram tests of amino acidSchiff bases complexes showed better results than some known antibiotics. Especially Cu(II) complexes were more potent bacteridal than all of the substances synthesized. Furthermore a mechanism of reaction was offered in the explanation of these observation. Some of the compounds exhibited activity comparable to Ketoconazole, Ampicillin, Tetracycline, Penicillin, Gentamisin and Chloroamphenicol.

Keywords

: Schiff base Amino acid Metal complexes Antimicrobial activity Radical

References

  • References
  • R. Eglof, P. Piotr, B. Bogumil, B. Franz, Curr Org. Chem. 13 (2009) 241-249.
  • G. Ellis, L. Chang, B. Cogionis, D. Daneman, Clin. Chem. 43 (1997) 2437-2439.
  • A.R. Fakhari, A.R. Khorrami, H. Naeimi, Talanta 66 (2005) 813-817.
  • U. Abram, R. Alberto, J Braz Chem Soc 17 (2006) 1486-1500.
  • M. Gharagozlou, D.M. Boghaei, Spectrochim Acta A 71 (2008) 1617-1622.
  • R.M. Wang, C.J. Hao, Y.P. Wang, S.B. Li, J Mol Catal A-Chem 147 (1999) 173-178.
  • W.K. Jung, H.C. Koo, K.W. Kim, S. Shin, S.H. Y.H Kim, Park Appl Environ Microb 74 (2008) 2171-2178.
  • A.P. Mishra, M. Soni Metal-Based Drugs 2008 ID 875410 (2008) 1-7.
  • S.A. Manley, S. Byrns, A.W. Lyon, P. Brown, J. Gailer, J Biol Inorg Chem 14 (2009) 61-74.
  • S.J. Lippard, J.M. Berg, Principles of Bioinorganic Chemistry, University Science Books, Mill Valley, CA, USA, (1994) p 64-276.
  • A.A. Abd El-Raady, T. Nakajima, Ozone-Scı Eng 27 (2005) 11-18.
  • S. Kobayashi, K. Ueda, T. Komano, Agric Biol Chem 54 (1990) 69-76.
  • D. Nartop, P. Gürkan, N. Sarı, S. Çete,. J Coord Chem 61 (2008) 3516-3524.
  • N. Sarı, J Macromol Sci A 43 (2006) 1609-1618.
  • N. Sari, P. Gürkan, S. Arslan, Trans Metal Chem 28 (2003) 468-474.
  • J.R. Anacona, I. Osorio, Transit Metal Chem 33 (2008) 517-521.
  • I. Şakiyan, Trans Metal Chem 32 (2007) 131-135.
  • I. Kaya, A. Bilici, M. Gul, Polym advan technol 19 (2008) 1154-1163.
  • N. Sarı, P. Gürkan, S. Çete, I. Şakiyan, Russ J Coord Chem 32 (2006) 511-517.
  • N. Sarı, P. Gürkan, Trans Metal Chem 28 (2003) 687-693.
  • N.S. Agar, J.R. Mahoney, J.W. Eaton, Biochem-Pharmacol 41 (1991) 985-993.
  • H. Zhang, C. Andrekopoulos, J. Joseph, J. Crow, B. Kalyanaraman, Free Radical Bio Med 36 (2004) 1355-1365.
  • S.I. Liochev, I. Fridovich, J Biol Chem 277 (2002) 34674-34678.
  • Z.H. Zhao, Y. Sakagami, T. Osaka, Can. J. Microbiol 44 (1998) 441-447.
  • S.P. Denyer, G.S.A.B Stewart, Int Biodeter Biodegr 41 (1998) 261-268.
There are 26 citations in total.

Details

Primary Language English
Subjects Engineering
Journal Section Chemistry
Authors

Elif Loğoğlu

Elif Aynacı Koyuncu This is me

Münteha Nur Sonuç Karaboğa This is me

Nursen Sarı

Publication Date June 20, 2016
Published in Issue Year 2016 Volume: 29 Issue: 2

Cite

APA Loğoğlu, E., Koyuncu, E. A., Sonuç Karaboğa, M. N., Sarı, N. (2016). Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes. Gazi University Journal of Science, 29(2), 303-307.
AMA Loğoğlu E, Koyuncu EA, Sonuç Karaboğa MN, Sarı N. Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes. Gazi University Journal of Science. June 2016;29(2):303-307.
Chicago Loğoğlu, Elif, Elif Aynacı Koyuncu, Münteha Nur Sonuç Karaboğa, and Nursen Sarı. “Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes”. Gazi University Journal of Science 29, no. 2 (June 2016): 303-7.
EndNote Loğoğlu E, Koyuncu EA, Sonuç Karaboğa MN, Sarı N (June 1, 2016) Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes. Gazi University Journal of Science 29 2 303–307.
IEEE E. Loğoğlu, E. A. Koyuncu, M. N. Sonuç Karaboğa, and N. Sarı, “Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes”, Gazi University Journal of Science, vol. 29, no. 2, pp. 303–307, 2016.
ISNAD Loğoğlu, Elif et al. “Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes”. Gazi University Journal of Science 29/2 (June 2016), 303-307.
JAMA Loğoğlu E, Koyuncu EA, Sonuç Karaboğa MN, Sarı N. Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes. Gazi University Journal of Science. 2016;29:303–307.
MLA Loğoğlu, Elif et al. “Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes”. Gazi University Journal of Science, vol. 29, no. 2, 2016, pp. 303-7.
Vancouver Loğoğlu E, Koyuncu EA, Sonuç Karaboğa MN, Sarı N. Synthesis and A Suggestion Mechanism on Biological Evaluation of Amino Acid-Schiff Base Ligands and Co(II), Cu(II) and Ni(II) Complexes. Gazi University Journal of Science. 2016;29(2):303-7.