Abstract
Let $R$ be a $\ast$-prime ring with characteristic not 2, $U$ be a nonzero $\ast$-$(\sigma,\tau)$-Lie ideal of $R$ and $d$ be a nonzero derivation of $R$. Suppose $\sigma$, $\tau$ be two automorphisms of $R$ such that $\sigma d=d\sigma$, $\tau d=d\tau$ and $\ast$ commutes with $\sigma,\tau,d$. In the present paper it is shown that if $d^2(U)=(0)$, then $U\subset Z$.