An Overview on Proteomic Studies

Year 2020, Volume: 40 Issue: 1, 48 - 58, 01.01.2020

Merve Nenni Mustafa Çelebier , İncilay Süslü

Abstract

Proteomics deals with the analysis, identification and functions of all proteins encoded by genes in the organism, tissue and cell under certain conditions. Today, it is known that not only genome analysis is sufficient in illuminating any biochemical process, but instead, a holistic evaluation including proteom analysis is rational. In this review study, an overview of the process starting from the first hypotheses about genes to proteomic studies today is presented.

Keywords

Protein, Proteomics, Genomics, 2 dimensional gel electrophoresis

Proteomik Çalışmalara Genel Bakış

Abstract

Proteomik; belirli şartlarda organizmada, dokuda ve hücre içerisinde genler tarafından kodlanan tüm proteinlerin analizi, tanımlanması ve fonksiyonlarıyla ilgilenir. Günümüzde herhangi bir biyokimyasal sürecin aydınlatılmasında yalnızca genom analizinin yeterli olmadığı ve bunun yerine proteom analizlerini de içine alan bütünsel bir değerlendirmenin akılcı olduğu bilinmektedir. Bu derleme çalışmasında, genlerle ilgili ortaya atılan ilk hipotezlerden başlayıp günümüzdeki proteomik çalışmalara kadar gelişen süreç üzerine genel bir bakış sunulmaktadır.

Keywords

Protein, Proteomik, Genomik, 2 boyutlu jel elektroforez

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