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Meme Kitlelerinde Tru-Cut Biyopsinin Yararlılığı

Year 2015, Volume: 12 Issue: 1, 73 - 77, 15.04.2015

Abstract

Amaç: Bu çalışmanın amacı, meme kitlelerinde ultrasonografi kılavuzluğunda yapılan tru-cut biyopsinin
tanısal yararlılığını araştırmaktır.
Metod: Kasım-2009 ile Mayıs-2014 tarihleri arasında hastanemiz Radyoloji Bölümünde ultrasonografik ve
mamografik olarak memede kitlesel lezyon saptanan ve ultrasonografi kılavuzluğunda tru-cut biyopsisi
yapılan 103 ardışık kadın olgunun kayıtları retrospektif olarak incelendi. Bu lezyonlarda radyolojikpatolojik tanısal uyum ve memedeki yerleşimleri değerlendirildi.
Bulgular: Olguların ortalama yaşı 47 idi. Lezyon büyüklüğü 5 mm ile 80 mm arasında değişmekte olup
ortalama boyut 20,45 mm'ydi. Kitlelerin %52.4'ü sağ memede, %47,6'sı sol memede olup en sık üst dış
kadran (%49,5) yerleşimliydi. Üst iç kadranda %18,4, alt iç kadranda %8,7, alt dış kadranda %18,4 oranda
izlenirken, lezyonların sadece %4,9'u retroareolar bölgeye yerleşimliydi. Malign ve benign lezyonların
memede yerleşimleri arasında istatistiksel fark izlenmedi. Histopatolojik değerlendirmede lezyonların 53'ü
(%51,4) benign ve 50'si (%48,6) maligndi. Lezyonların radyolojik sınıflaması ile patolojik tanıları arasında
BIRADS 3 ve BIRADS 5'te tam uyum mevcuttu. BIRADS 4 olarak sınıflandırılan 20 olgunun 9'u benign tanı
alırken 11 tanesi malign tanı aldı.
Sonuç: Ultrasonografi kılavuzluğunda yapılan tru-cut biyopsileri, hızlı uygulanan ve hızlı sonuç alınan,
daha güvenilir preoperatif planlamaya olanak sağlayan, yüksek güvenilirlikli bir yöntemdir

References

  • 1. Menezes GL, Knuttel FM, Stehouwer BL, Pijnappel RM, van den Bosch MA. Magnetic resonance imaging in breast cancer: A literature review and future perspectives. World J Clin Oncol 2014;5(2):61-70. 2. Smallenburg VVB, Nederend J, Voogd AC, Coebergh JW, van Beek M, Jansen FH, Louwman WJ, Duijm LE. Trends in breast biopsies for abnormalities detected at screening mammography: a population-based study in the Netherlands. British Journal of Cancer 2013;109(1):242-48. 3. Hatmaker AR, Donahue RMJ, Tarpley JL, Pearson AS. Cost-effective use of breast biopsy techniques in a veterans health care system. The American Journal of Surgery 2006;192(5):37-41. 4. Hukkinen K, Kivisaari L, Heikkila PS, Von Smitten K, Leidenius M. Unsuccessful preoperative biopsies, fine needle aspiration cytology or core needle biopsy, lead to increased costs in the diagnostic workup in breast cancer. Acta Oncol 2008;47(6):1037-45. 5. Verkooijen HM, Peeters PH, Buskens E, Koot VC, Borel Rinkes I, Mali WP, van Vroonhoven TJ. Diagnostic accuracy of large-core needle biopsy for nonpalpable breast disease: a meta-analysis. Br J Cancer 2000;82(5):1017-21. 6. Radhakrishna S, Gayathri A, Chegu D. Needle core biopsy for breast lesions: An audit of 467 needle core biopsies. Indian J Med Paediatr Oncol 2013;34(4):252- 56. 7. Varas X, Leborgne F, Leborgne JH. Nonpalpable, probably benign lesions: role of follow-up mammography. Radiology 1992;184(2):409-14. 8. Sickles EA. Nonpalpable, circumscribed, noncalcified solid breast masses: likelihood of malignancy based on lesion size and age of patient. Radiology 1994;192(2):439-42. 9. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology 1995;196(1):123-34. 10. Costantini M, Belli P, Lombardi R, Franceschini G, Mule A, Bonomo L. Characterization of solid breast masses: use of the sonographic imaging reporting and data system lexicon. J Ultrasound Med 2006;25(5):649- 59. 11. Hong AS, Rosen EL, Soo MS, Baker JA. RADS for sonography: positive and negative predictive values of sonographic features. Am J Roentgenol 2005;184(4):1260- 65. 12. Brunner AH, Sagmeister T, Kremer J, Riss P, Brustmann H. The accuracy of frozen section analysis in ultrasoundguided core needle biopsy of breast lesions. BMC Cancer 2009; 24(9):341. 13. Homesh NA, Issa MA, El-Sofiani HA. The diagnostic accuracy of fine needle aspiration cytology versus core needle biopsy for palpable breast lump(s). Saudi Med J 2005;26(1):42-46. 14. Gukas ID, Nwana EJ, Ihezue CH, Momoh JT, Obekpa PO. Tru-cut biopsy of palpable breast lesions: a practical option for pre-operative diagnosis in developing countries. Cent Afr J Med 2000;46(5):127-30. 15. Jung HK, Moon HJ, Kim MJ, Kim EK. Benign core biopsy of probably benign breast lesions 2 cm or larger: Correlation with excisional biopsy and long-term follow-up. Ultrasonography 2014;33(3):200-05

The Benefit of Tru-Cut Biopsy in Breast Masses

Year 2015, Volume: 12 Issue: 1, 73 - 77, 15.04.2015

Abstract

Backgrounds: To investigate the diagnostic benefit of tru-cut biopsy made under ultrasonography guidance
in breast masses.
Methods: A retrospective review was made of the records of 103 consecutive female patients who
underwent tru-cut biopsy under ultrasonography guidance for a mass lesion determined in the breast
mammographically and ultrasonographically in our hospital Radiology Department between November
2009 and May 2011. Radiological and pathological conformity and location in the breast were evaluated in
these lesions. Results: The mean age of the patients was 47 years. The mean size of the lesion was 20.45mm (range, 5-
80mm). The mass was located in the right breast in 52.4% of cases and in the left breast in 47.6% and most
frequently in the upper external quadrant (49.5%). Location was observed in the upper internal quadrant in
18.4%, in the lower internal quadrant at 8.7% and the lower external quadrant at 18.4% with only 4.9%
located in the retroareolar region. No statistically significant difference was determined between malignant
and benign lesions in respect of location. In the histopathological evaluation, 53 (51.4%) lesions were benign
and 50 (48.6%) were malignant. There was full conformity to BIRADS 3 and BIRADS 5 between the
pathological diagnoses and the radiological grading of the lesions. Of 20 cases classified as BIRADS 4, 9
were diagnosed as benign and 11 as malignant.
Conclusions: Tru-cut biopsy made under ultrasonography guidance is a highly reliable method which can be
quickly applied to give rapid results, allowing preoperative planning to be made more safely.

References

  • 1. Menezes GL, Knuttel FM, Stehouwer BL, Pijnappel RM, van den Bosch MA. Magnetic resonance imaging in breast cancer: A literature review and future perspectives. World J Clin Oncol 2014;5(2):61-70. 2. Smallenburg VVB, Nederend J, Voogd AC, Coebergh JW, van Beek M, Jansen FH, Louwman WJ, Duijm LE. Trends in breast biopsies for abnormalities detected at screening mammography: a population-based study in the Netherlands. British Journal of Cancer 2013;109(1):242-48. 3. Hatmaker AR, Donahue RMJ, Tarpley JL, Pearson AS. Cost-effective use of breast biopsy techniques in a veterans health care system. The American Journal of Surgery 2006;192(5):37-41. 4. Hukkinen K, Kivisaari L, Heikkila PS, Von Smitten K, Leidenius M. Unsuccessful preoperative biopsies, fine needle aspiration cytology or core needle biopsy, lead to increased costs in the diagnostic workup in breast cancer. Acta Oncol 2008;47(6):1037-45. 5. Verkooijen HM, Peeters PH, Buskens E, Koot VC, Borel Rinkes I, Mali WP, van Vroonhoven TJ. Diagnostic accuracy of large-core needle biopsy for nonpalpable breast disease: a meta-analysis. Br J Cancer 2000;82(5):1017-21. 6. Radhakrishna S, Gayathri A, Chegu D. Needle core biopsy for breast lesions: An audit of 467 needle core biopsies. Indian J Med Paediatr Oncol 2013;34(4):252- 56. 7. Varas X, Leborgne F, Leborgne JH. Nonpalpable, probably benign lesions: role of follow-up mammography. Radiology 1992;184(2):409-14. 8. Sickles EA. Nonpalpable, circumscribed, noncalcified solid breast masses: likelihood of malignancy based on lesion size and age of patient. Radiology 1994;192(2):439-42. 9. Stavros AT, Thickman D, Rapp CL, Dennis MA, Parker SH, Sisney GA. Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology 1995;196(1):123-34. 10. Costantini M, Belli P, Lombardi R, Franceschini G, Mule A, Bonomo L. Characterization of solid breast masses: use of the sonographic imaging reporting and data system lexicon. J Ultrasound Med 2006;25(5):649- 59. 11. Hong AS, Rosen EL, Soo MS, Baker JA. RADS for sonography: positive and negative predictive values of sonographic features. Am J Roentgenol 2005;184(4):1260- 65. 12. Brunner AH, Sagmeister T, Kremer J, Riss P, Brustmann H. The accuracy of frozen section analysis in ultrasoundguided core needle biopsy of breast lesions. BMC Cancer 2009; 24(9):341. 13. Homesh NA, Issa MA, El-Sofiani HA. The diagnostic accuracy of fine needle aspiration cytology versus core needle biopsy for palpable breast lump(s). Saudi Med J 2005;26(1):42-46. 14. Gukas ID, Nwana EJ, Ihezue CH, Momoh JT, Obekpa PO. Tru-cut biopsy of palpable breast lesions: a practical option for pre-operative diagnosis in developing countries. Cent Afr J Med 2000;46(5):127-30. 15. Jung HK, Moon HJ, Kim MJ, Kim EK. Benign core biopsy of probably benign breast lesions 2 cm or larger: Correlation with excisional biopsy and long-term follow-up. Ultrasonography 2014;33(3):200-05
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Details

Primary Language Turkish
Journal Section Research Article
Authors

Önder Yeniçeri

Önder Özcan

Neşat Çullu

Mehmet Deveer

Publication Date April 15, 2015
Submission Date December 1, 2014
Acceptance Date January 13, 2015
Published in Issue Year 2015 Volume: 12 Issue: 1

Cite

Vancouver Yeniçeri Ö, Özcan Ö, Çullu N, Deveer M. Meme Kitlelerinde Tru-Cut Biyopsinin Yararlılığı. Harran Üniversitesi Tıp Fakültesi Dergisi. 2015;12(1):73-7.

Harran Üniversitesi Tıp Fakültesi Dergisi  / Journal of Harran University Medical Faculty