Posterior Sirkülasyon İnfarktlarının Risk Faktörleri, Etyoloji Ve Klinik Özellikleri Bakınmından Cisiyetler Arası Farlılıkları: Gözlemsel Çalışma
Abstract
Amaç: Bu çalışmada, posterior sirkülasyon infarktı (POCI) olan hastaların demografik özellikleri, risk
faktörleri, etiyolojik ve klinik profilleri gözden geçirerek bu parametreler bakımından cinsiyetler arasında
farklılık olup olmadığını değerlendirmeyi amaçladık.
Materyal ve Metod: Bu çalışmaya Başkent Üniversitesi Adana Araştırma ve Uygulama Hastanesi,
Kahramanmaraş Özel Hayat Hastanesi ve Şanlıurfa Mehmet Akif İnan Eğitim Araştırma Hastanesine 2014
yılı ilk 6 aylık süre içerisinde başvuran ve posterior sirkülasyon infarktları olan ardışık 11'i (% 26.2) kadın ve
31'i (%73.8) erkek toplam 42 hasta dahil edildi. Yaş, eğitim durumu, risk faktöleri, inme etiyolojisi ve ölüm
oranı bakımından kadın ve erkek hastalar karşılaştırıldı.
Bulgular: Kadın hastalarda erkek hastalara göre; geçici iskemik atak, mortalite oranı daha yüksek saptandı.
Risk faktörlerinden koroner arter hastalığı, konjestif kalp yetmezliği, atrial fibrilasyon, hiperlipidemi,
diabetes mellitus, hiperlipidemi varlığı daha yüksek oranda saptandı.
Sonuç: Çalışmamızdaki bulgular, POCI sendromlu hastalarda cinsiyetin kadın olmasının inmenin klinik
seyrini olumsuz yönde etkileyebileceğini düşündürmektedir.
References
- 1) Dalyan M, Çakçı A. inme rehabilitasyonu In: Oğuz H, Dursun E, Dursun N, editörler. Tıbbi Rehabilitasyon. istanbul: Nobel tıp kitapevleri 2004; p: 589-618. 2) Hankey GJ. Potential new risk factors for ischemic stroke what is their potential? Stroke 2006;37: 2181-8 3) Treatable lesions demostrated on vertebral angiography for posterior circulation İschaemic events. The British Journal Of Radiology. 1998;71 4) Vibo R, Korv J, Haldre S, Roose M. First-year results of the third stroke registry in Tartu,Estonia. Cerebrovasc Dis. 2004;18(3):227-31. 5) Amanda G. Thrift, PhD; Helen M Dewey, PhD; Richard AL Macdonell, MD; John J McNeil, PhD; Geoffrey A Donan, MD. Incidance of the Major Stroke Subtypes. Stroke. 2001;32: 1732-8. 6) Markus HS .Stroke genetics. Hum Mol Genet. 2011 Oct 15;20(R2):R124-31. 7) Bradley WG, Daroff BR, Fenichel GM, Marsden CD.Neurology in Clinical Practice. The Neurological Disorders. Third Edition.Vascular Diseases of The Nervous System 2000; 1125- 6. 8) Harold P, Adams JR. Secondary Prevention of Atherothrombotic Events After Ischemic Stroke. Mayo Clin Proc 2009; 84: 43-51. 9)Rexode KM. Emerging risk factors in women. Stroke 2010; 41: 9-11. 10) Goldstein LB, Bushnell CD, Adams RJ, et al. Guidelines fort he primary prevention of stroke. A guideline for healtcare professionals from the American Heart Association/American Stroke Association. Stroke 2011; 42: 517-84 11) Larsson SC, Virtamo I, Wolk A. Coffee Consumption and Risk of Stroke in Women. Stroke 2011; 42: 908-12. 12) De Reuck JL, Van Maele G. Seizures and epilepsy in patients with a posterior circulation infarct. J Stroke Cerebrovasc Dis 2012; 21: 1-4. 13) Primer: The Essentials of High Blood Pressure. Baltimore, Md: Lippincott, Williams & Wilkins; 1999:239 14)Bushnell CD. Stroke and the female brain. Nat Clin Pract Neurol 2008; 4: 22-33. 15)Probabilty of stroke:A risk profile from the Framingham study:Philip A.Wolf,MD;Ralph B;D'agostino,PhD;Albert J.Belnger,MA and William B.Kannel,MD.Stroke 1991;22:312-8 16) Manolio TA, Kronmal RA, Burke GL, et al. Shortterm predictors of incident stroke in older adults: the Cardiovascular Health Study. Stroke. 1996; 27: 1479–86. 17) Appelros P, Stegmayr B, Terent A. Sex differences in stroke epidemiology:A systematic review. Stroke 2009; 40:1082-90 18) Hart RG, Halperin JL, Pearce LA, et al. Stroke Prevention in Atrial Fibrillation Investigators. Lessons from the Stroke Prevention in Atrial Fibrillation trials. Ann Intern Med. 2003; 138: 831–8. 19) Foster A, Gass A, Kern R, Wolf ME, Ottomeyer C, Zohsel K, Hennerici M,Szabo K. Gender differences in acute ischemic stroke:etiology, stroke patterns and response to thrombolysis. Stroke 2009; 40:2428-32. 20) Yesilot NF, Koyuncu BA, Coban O, Tuncay R, Bahar SZ. Gender differencesin acute stroke:Istanbul medical school stroke registry. Neurol India 2011;59:174-9. 21) Smith MA, Lisabeth LD, Brown DL, Morgenstern LB. Gender comparisons of diagnostic evaluation for ischemic stroke patients. Neurology 2005; 65:8558. 22) Wassertheil-Smoller S. Stroke in women. Nutr Metab Cardiovasc Dis 2010; 20:419-25. 23) Reeves MJ, Bushnell CD, Howard G, Gargano JW, Duncan PW, Lynch G,Khatiwoda A, Lisabeth L. Sex differences in stroke:epidemiology, clinicalpresentation, medical care, and outcomes. Lancet Neurol 2008; 7:915-26. 24) Persky RW, Turtzo LC, McCullough LD. Stroke in Women: Disparities and Outcomes. Curr Cardiol Rep 2010; 12: 6-13.
Abstract
Objective: In this study, we evaluated the risk factors, demographic, clinical and etiological characteristics
of patients with total posterior circulation infarct (POCI) and we aimed to elucidate the impact of genderbased differences on these parameters.
Material and Methods: In this study, 42 ( 11 (26.2%) famele, 31 (73.8%) male) consecutive posterior
circulation infarct patients from which Başkent University Research and Training Hospital, Kahramanmaraş
Private Hayat Hospital, and Şanlıurfa Mehmet Akif İnan Research and Training Hospital were included for
the first six months of 2014. We compared the age, previous stroke, risk factors, education and the rate of
death between genders.
Results: Transient ischemic attack, the mortality rate was higher than female patients compared to male
patients; Risk factors for coronary artery disease, congestive heart failure, atrial fibrillation, hyperlipidemia,
diabetes mellitus and hyperlipidemia were higher in patints with total posterior circulation infarct (POCI).
Conclusion: The result of the present study indicated that female gender has a negative effect on clinical
outcome of POCI.
References
- 1) Dalyan M, Çakçı A. inme rehabilitasyonu In: Oğuz H, Dursun E, Dursun N, editörler. Tıbbi Rehabilitasyon. istanbul: Nobel tıp kitapevleri 2004; p: 589-618. 2) Hankey GJ. Potential new risk factors for ischemic stroke what is their potential? Stroke 2006;37: 2181-8 3) Treatable lesions demostrated on vertebral angiography for posterior circulation İschaemic events. The British Journal Of Radiology. 1998;71 4) Vibo R, Korv J, Haldre S, Roose M. First-year results of the third stroke registry in Tartu,Estonia. Cerebrovasc Dis. 2004;18(3):227-31. 5) Amanda G. Thrift, PhD; Helen M Dewey, PhD; Richard AL Macdonell, MD; John J McNeil, PhD; Geoffrey A Donan, MD. Incidance of the Major Stroke Subtypes. Stroke. 2001;32: 1732-8. 6) Markus HS .Stroke genetics. Hum Mol Genet. 2011 Oct 15;20(R2):R124-31. 7) Bradley WG, Daroff BR, Fenichel GM, Marsden CD.Neurology in Clinical Practice. The Neurological Disorders. Third Edition.Vascular Diseases of The Nervous System 2000; 1125- 6. 8) Harold P, Adams JR. Secondary Prevention of Atherothrombotic Events After Ischemic Stroke. Mayo Clin Proc 2009; 84: 43-51. 9)Rexode KM. Emerging risk factors in women. Stroke 2010; 41: 9-11. 10) Goldstein LB, Bushnell CD, Adams RJ, et al. Guidelines fort he primary prevention of stroke. A guideline for healtcare professionals from the American Heart Association/American Stroke Association. Stroke 2011; 42: 517-84 11) Larsson SC, Virtamo I, Wolk A. Coffee Consumption and Risk of Stroke in Women. Stroke 2011; 42: 908-12. 12) De Reuck JL, Van Maele G. Seizures and epilepsy in patients with a posterior circulation infarct. J Stroke Cerebrovasc Dis 2012; 21: 1-4. 13) Primer: The Essentials of High Blood Pressure. Baltimore, Md: Lippincott, Williams & Wilkins; 1999:239 14)Bushnell CD. Stroke and the female brain. Nat Clin Pract Neurol 2008; 4: 22-33. 15)Probabilty of stroke:A risk profile from the Framingham study:Philip A.Wolf,MD;Ralph B;D'agostino,PhD;Albert J.Belnger,MA and William B.Kannel,MD.Stroke 1991;22:312-8 16) Manolio TA, Kronmal RA, Burke GL, et al. Shortterm predictors of incident stroke in older adults: the Cardiovascular Health Study. Stroke. 1996; 27: 1479–86. 17) Appelros P, Stegmayr B, Terent A. Sex differences in stroke epidemiology:A systematic review. Stroke 2009; 40:1082-90 18) Hart RG, Halperin JL, Pearce LA, et al. Stroke Prevention in Atrial Fibrillation Investigators. Lessons from the Stroke Prevention in Atrial Fibrillation trials. Ann Intern Med. 2003; 138: 831–8. 19) Foster A, Gass A, Kern R, Wolf ME, Ottomeyer C, Zohsel K, Hennerici M,Szabo K. Gender differences in acute ischemic stroke:etiology, stroke patterns and response to thrombolysis. Stroke 2009; 40:2428-32. 20) Yesilot NF, Koyuncu BA, Coban O, Tuncay R, Bahar SZ. Gender differencesin acute stroke:Istanbul medical school stroke registry. Neurol India 2011;59:174-9. 21) Smith MA, Lisabeth LD, Brown DL, Morgenstern LB. Gender comparisons of diagnostic evaluation for ischemic stroke patients. Neurology 2005; 65:8558. 22) Wassertheil-Smoller S. Stroke in women. Nutr Metab Cardiovasc Dis 2010; 20:419-25. 23) Reeves MJ, Bushnell CD, Howard G, Gargano JW, Duncan PW, Lynch G,Khatiwoda A, Lisabeth L. Sex differences in stroke:epidemiology, clinicalpresentation, medical care, and outcomes. Lancet Neurol 2008; 7:915-26. 24) Persky RW, Turtzo LC, McCullough LD. Stroke in Women: Disparities and Outcomes. Curr Cardiol Rep 2010; 12: 6-13.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Research Article |
| Authors | |
| Publication Date | December 15, 2014 |
| Submission Date | August 15, 2014 |
| Acceptance Date | September 24, 2014 |
| Published in Issue | Year 2014 Volume: 11 Issue: 3 |
Cite
Harran Üniversitesi Tıp Fakültesi Dergisi / Journal of Harran University Medical Faculty