Üst Hava Yolu Obstrüksiyonu Nedeniyle Adenotonsillektomi Yapılan Pediatrik Hastaların Kan Parametrelerinin Analizi

Year 2024, Volume: 21 Issue: 2, 184 - 189, 29.08.2024

Müslüm Ayral , Servet Erdemes

https://doi.org/10.35440/hutfd.1476639

Abstract

Amaç: Pediatrik yaş grubunda obstrüktif uyku apne sendromu (OSAS)’ nun en sık görülen nedeni adenotonsiller hipertrofidir. Çalışmamızda üst solunum yolu obstrüksiyonu nedeniyle adenotonsillektomi yapılan hastalarda kan parametrelerindeki inflamatuar değişiklikleri göstermeyi amaçladık.
Materyal ve metod: Tanıklı apne nedeniyle polikliniğe başvuran adenotonsiller hipertrofi nedeniyle opere edilen 50 hasta retrospektif olarak incelendi. Hastaların ameliyat öncesi ve ameliyat sonrası 6. Ay kontrolünde bakılan Tam kan sayımı (CBC) parametreleri değerlendirildi. Çalışmamızda Nötrofil lenfosit oranı (NLR), platellet lenfosit oranı (PLR), ortalama platellet hacmi (MPV), platellet sayısı ve WBC’ nin MPV'ye oranı (WMR), kırmızı kan hücresi dağılım genişliği (RDW), platelet dağılım genişliği (PDW) değerlerinin ameliyat sonrasındaki değişimi incelendi.
Bulgular: Çalışma %36’sı (n=18) kız, %64’ü (n=32) erkek olmak üzere toplam 50 olgu ile yapılmıştır. Olguların yaşları 5 ile 13 arasında değişmekte olup, ortalama yaş 9,28±2,53’tür. Çalışmamızda ameliyat sonrası WMR, MPV, NLR ölçümlerindeki düşüş istatistiksel olarak anlamlı saptanmıştır (p<0,01). Ayrıca PDW ölçümlerinde de düşüş istatistiksel olarak anlamlı saptanmıştır (p<0,05). Çalışmamızdaki RDW ve PLR ölçümü değişimleri istatistiksel olarak anlamlı farklılık göstermemektedir (p>0,05).
Sonuç: Bu çalışmamız bize adenotonsiller hipertrofi nedeniyle üst solunum yolu obstrüksiyonu olan hastaların ameliyat sonrası protrombotik değerlerinde düzelme olduğunu göstermektedir. Sonuçlarımız üst solunum yolu obstrüksiyonu olan hastalarda cerrahinin etkililiğini ve gerekliliğini göstermektedir.

Keywords

Adenotonsillektomi, Obstüriktif uyku apne Sendromu, Çocuk hasta, Kan parametreleri

Ethical Statement

Harran Üniversitesi Klinik Araştırmalar Etik Kurulu tarafından 15.04.2024 tarih ve HRÜ/24.04.03 karar numarası ile onaylandı.

Supporting Institution

Bu çalışma yazarların kendi çalışması olup, herhangi bir kurum ya da vakıftan maddi destek alınmamıştır

Blood Parameter Analysis of Pediatric Patients Who Underwent Adenotonsillectomy Due to Upper Airway Obstruction

Abstract

Background: The most common cause of obstructive sleep apnea syndrome (OSAS) in the pediatric age group is adenotonsillar hypertrophy. In our study, we aimed to investigate inflammatory changes in blood parameters in patients who underwent adenotonsillectomy due to upper respiratory tract obst-ruction.
Materials and Methods: 50 patients who were operated on due to adenotonsillar hypertrophy, who applied to the outpatient clinic with a complaint of witnessed apnea, were retrospectively examined. Complete blood count (CBC) parameters of the patients before surgery and at the 6th month postope-rative follow-up were evaluated. In our study, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), mean platelet volume (MPV), the ratio of WBC to MPV (WMR), red blood cell distribution width (RDW), platelet distribution width (PDW). The changes in ) values after surgery were examined.
Results: The study was conducted with a total of 50 cases, 36% (n=18) of which were girls and 64% (n=32) were boys. The ages of the cases ranged between 5 and 13, and the average age was 9.28±2.53. In our study, the decrease in WMR, MPV, and NLR measurements after surgery was found to be statisti-cally significant (p<0.01). Additionally, the decrease in PDW measurements was found to be statistically significant (p<0.05). RDW and PLR measurement changes in our study do not show a statistically signifi-cant difference (p>0.05).
Conclusions: This study showed that prothrombotic values improved after adenotonsillectomy in pa-tients with upper airway obstruction due to adenotonsillar hypertrophy. Our results demonstrate the effectiveness and necessity of surgery in patients with upper airway obstruction.

Keywords

Adenotonsillectomy, Obstructive sleep apnea syndrome, Pediatric patient, Blood parameters

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