Efficiency of Systemic Immune Inflammation Index in Predicting Organ Loss in Testicular Torsion

Year 2025, Volume: 22 Issue: 1, 179 - 183, 26.03.2025

Mehmet Demir , İsmail Yağmur

https://doi.org/10.35440/hutfd.1627870

Abstract

Background: This study aims to evaluate the efficacy of the systemic immune-inflammation index (SII) in predicting testicular loss in patients undergoing surgical intervention for testicular torsion (TT).
Materials and Methods: The data of patients diagnosed with TT and treated surgically between January 2012 and December 2023 were retrospectively analyzed. Patients were divided into two groups based on the type of surgical intervention: orchiopexy and orchiectomy. Demographic data, symptom duration, and complete blood count parameters were recorded. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and SII were calculated. Hematological and clinical parameters were compared between the two groups.
Results: A total of 107 patients were included in the study, with 66 undergoing orchiopexy and 41 undergoing orchiectomy. Multivariate analyses revealed that symptom duration, white blood cell count (WBC), PLR, and SII were independent and significant predictors of organ loss (p<0.05). Specifically, symptom duration and SII demonstrated high efficacy in predicting testicular loss (AUC=0.942 and 0.658).
Conclusions: SII may serve as an effective biomarker in predicting testicular loss in TT. As a rapid and cost-effective method, it can guide surgical decision-making, particularly in settings with limi-ted access to imaging modalities.

Keywords

Testicular torsion, Orchiectomy, Systemic immune-inflammation index, Orchiopexy, Platelet-to-lymphocyte ratio

Testis Torsiyonunda Organ Kaybını Öngörmede Sistemik İmmün İnflamasyon İndeksinin Etkinliğinin Değerlendirilmesi

Abstract

Amaç: Bu çalışma, testis torsiyonu (TT) nedeniyle cerrahi müdahale yapılan hastalarda sistemik immün inflamasyon indeksinin (SII) testis kaybını öngörmedeki etkinliğini değerlendirmeyi amaç-lamaktadır.
Materyal ve metod: Ocak 2012-Aralık 2023 tarihleri arasında TT tanısı ile cerrahi uygulanan hastala-rın verileri retrospektif olarak incelendi. Hastalar, cerrahi sonrası orşiopeksi ve orşiektomi yapılan-lar olarak iki gruba ayrıldı. Demografik veriler, semptom süresi ve tam kan sayımı değerleri kayde-dildi. Nötrofil-lenfosit oranı (NLO), platelet-lenfosit oranı (PLO) ve SII hesaplandı. İki grup arasında hematolojik ve klinik parametreler karşılaştırıldı.
Bulgular: Çalışmaya toplamda 107 hasta dahil edildi; 66'sına orşiopeksi, 41'ine orşiektomi uygulan-dı. Çok değişkenli analizlerde semptom süresi, WBC, PLO ve SII’nin organ kaybını öngörmede bağımsız ve anlamlı belirteçler olduğu saptandı(p<0,05). Özellikle semptom süresi ve SII'nin testis kaybını öngörmede yüksek etkinlikte olduğu görüldü (AUC=0,942 ve 0,658).
Sonuç: SII, TT'da testis kaybını öngörmede etkili bir biyobelirteç olabilir. Hızlı ve düşük maliyetli bir yöntem olarak, özellikle görüntüleme yöntemlerine erişimin sınırlı olduğu durumlarda cerrahi karar süreçlerine rehberlik edebilir.

Keywords

Testis torsiyonu, Orşiektomi, İmmün inflamasyon indeksi, Orşiepoksi, Platelet-lenfosit oranı.

Ethical Statement

Çalışma için etik kurul onayı alınmıştır

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