Usage of Detoxification Enzyme Glutathione-S-Transferases over Galleria mellonella L. (Lepidoptera: Pyralidae) as Biomarkers of Insecticide Resistance

Year 2018, Volume: 4 Issue: 1, 1 - 10, 30.09.2018

Serkan Sugeçti , Ender Büyükgüzel , Kemal Büyükgüzel

Abstract

Insecticides are preferred because of their easy
applicability in combating pest insects and their short-term results.
Insecticides used over dose and unconsciously in agricultural areas cause
ecological damage. Also; the use of over dose insecticides in agricultural
areas has led to the development of insect resistance. Since the resistance
mechanism developed is genetic, it is transmitted to later fertilizers. For
this reason, it is important to apply the insecticides in the restricted areas
and in the optimal amount. Insects increase their detoxification capacities to
protected themselves from insecticides. Detoxification mechanisms are based on
the breakdown of insecticides before reaching the target area. The most
important detoxification enzyme in insects are Glutathion-S-Transferases (GST).
GST enzyme in insects has a role in protection of cellular membranes against
oxidative degradation as well as detoxification mechanism. Galleria mellonella may be used as a model organism for
understanding the insecticide resistance mechanism.

Keywords

Galleria mellonella, detoxification, oxidation, antioxidant, toxicology

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