İNSANLARDAKİ COVID-19 YABAN HAYVANLARINDA RİSK OLUŞTURUYOR MU?

Year 2022, Volume: 5 Issue: 2, 543 - 556, 30.09.2022

Basak Hanedan , Ali Bilgili , Nigar Abbasova

https://doi.org/10.52538/iduhes.1162455

Abstract

Dünya çapında insanların önemli bir kısmının SARS-CoV-2 ile enfekte olmaları ve semptomlar görülmeden önce enfeksiyonu bilinmeyen şekilde yayabilmelerinden dolayı insanların yaban hayvanlarına COVID-19’u yayma riskleri bulunmaktadır. COVID-19’a yaban hayvanlarının duyarlılığının değerlendirildiği çalışmada primatlar, takiben karnivorlar, memeli deniz hayvanları, yabani kemirgenlerin yüksek potansiyel gösterdiği, laboratuvar kemirgenlerinin düşük riskte olduğu, kuşlar, reptiller ve amfibilerin de düşük riskte olduğu bildirildi. Kaplan, aslan, puma ve kar leoparına insanlardan COVID-19’un bulaştırıldığı bildirildi. COVID-19’la enfekte vizonların etkenleri insanlara ve kedilere bulaştırdığı gösterildi. COVID-19’un yabani gelincik ve vizonlara bulaşması halinde hayvanlar daha sonra devamlı rezervuar konaklar haline gelebilir ve insanlara ve diğer hayvan türlerine enfeksiyonu bulaştırabilir. Yaban hayvanları insanlarla yakın temastadır. Dolayısıyla COVID-19’a bağlı bulaşma olup olmadığının bilinmesi önemlidir. Bu çalışma kapsamında son yıllara ait çok sayıda bilimsel kaynak incelenerek insanlardan yaban hayvanlarına, yaban hayvanlarından tekrar insan ya da diğer hayvanlara COVID-19’un bulaştırılıp bulaştırılmadığı konularında ayrıntılı bilgiler verildi. Ayrıca insanlardan yaban hayvanlarına COVID-19’un bulaşmasının engellenmesine yönelik yapılması gereken uygulamalar hakkında bilgiler sunuldu.

Keywords

SARS-CoV-2, İnsan, Yaban Hayvanları, Bulaşma, SARS-CoV-2, İnsan, Yaban Hayvanları, Bulaşma

References

• Referans1 Ahmad, T., Haroon Dhama, K., Sharun, K., Khan, F. M., Ahmed, I., … & Hui, J. (2020). Biosafety and biosecurity approaches to restrain/contain and counter SARS-CoV-2/COVID-19 pandemic: a rapid-review. Turkish Journal of Biology, 44, 132-145.
• Referans2 Andersen, K. G., Rambaut, A., Lipkin, W. I., Holmes, E. C., & Garry, R. F. (2020). The proximal origin of SARS-CoV-2. Nature Medicine, 26(4), 450-452.
• Referans3 Bartlett, S. L., Diel, D. G., Wang, L., Zec, S., Laverack, M., Martins, M., … & Calle, P. P. (2021). SARS-CoV-2 infection and longitudinal fecal screening in Malayan tigers (Panthera tigris jacksoni), Amur tigers (Panthera tigris altaica), and African lions (Panthera leo krugeri) at the Bronx zoo, New York, USA. Journal of Zoo and Wildlife Medicine, 51(4), 733-744.
• Referans4 Bao, L., Deng, W., Huang, B., Gao, H., Liu, J., Ren, L., …. & Qin, C. (2020). The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice. Nature, 583(7818), 830-833.
• Referans5 Boni, M. F., Lemey, P., Jiang, X., Lam, T. T., Perry, B., Castoe, T., … & Robertson, D. L. (2020). Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic. Nature Microbiology, 5(11), 1408-1417.
• Referans6 Bonilauri, P., & Rugna, G. (2021). Animal coronaviruses and SARS-CoV-2 in animals, what do we actually know? Life, 11, 123. Doi: 10.3390/life11020123.
• Referans7 Bosco-Lauth, A. M., Root, J. J., Porter, S. M., Walker, A. E., Guilbert, L., Hawvermale, D., ... & Bowen, R. A. (2021). Peridomestic mammal susceptibility to severe acute respiratory syndrome coronavirus 2 infection. Emerging Infectious Diseases, 27(8), 2073.
• Referans8 Chavda, V. P., Feehan, J., & Apostolopoulos, V. (2021). A veterinary vaccine for SARS-CoV-2: the first COVID-19 vaccine for animals. Vaccines, 9(6), 631.
• Referans9 Cui, J., Li, F., & Shi, Z. L. (2019). Origin and evolution of pathogenic coronaviruses. Nature Reviews. Microbiology, 17, 181-192.
• Referans10 Cui, S., Liu, Y., Zhao, J., Peng, X., Lu, G., Shi, W., ... & Wang, Q. (2022). An updated review on SARS-CoV-2 infection in animals. Viruses, 14(7), 1527.
• Referans11 Damas, J., Hughes, G. M., Keough, K. C., Painter, C. A., Persky, N. S., Corbo, M., … & Lewin, H. A. (2020). Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates. Proceedings of the National Academy of Sciences of the United States of America, 117, 22311-22322.
• Referans12 Davoust, B., Guérin, P., Orain, N., Fligny, C., Flirden, F., Fenollar, F., ... & Edouard, S. (2022). Evidence of antibodies against SARS-CoV-2 in wild mustelids from Brittany (France). Tranboundary and Emerging Diseases, 1-8. Doi: 10.1111/tbed.14663.
• Referans13 Delahay, R., de la Fuente, J., Smith, G., Sharun, K., Snary, E., Giron, L. F., … & Gortazar, C. (2021). Assessing the risks of SARS-CoV-2 in wildlife. One Health Outlook, 3, 7. Doi: 10.1186/s42522-021-00039-6.
• Referans14 Deng, W., Bao, L., Gao, H., Xiang, Z., Qu, Y., Song, Z., … & Qin, C. (2020). Ocular conjunctival inoculation of SARS-CoV-2 can cause mild COVID-19 in rhesus macaques. Nature Communications, 11(1), 4400.
• Referans15 El Zowalaty, M. E., & Jarhult, J. D. From SARS to COVID-19: a previously unknown SARS-related coronavirus (SARS-CoV-2) of pandemic potential infecting humans-call for a One Health approach. One Health, 9, 100124. Doi: 10.1016/j.onehlt.2020.100124.
• Referans16 Everett, H. E., Lean, F. Z., Byrne, A. M., van Diemen, P. M., Rhodes, S., James, J., ... & Brookes, S. M. (2021). Intranasal infection of ferrets with SARS-CoV-2 as a model for asymptomatic human infection. Viruses, 13(1), 113.
• Referans17 Fernández-Bellon, H., Rodon, J., Fernández-Bastit, L., Almagro, V., Padilla-Solé, P., Lorca-Oró, C., ... & Vergara-Alert, J. (2021). Monitoring natural SARS-CoV-2 infection in lions (Panthera leo) at the Barcelona Zoo: Viral dynamics and host responses. Viruses, 13(9), 1683.
• Referans18 Gollakner, R., & Capua, I. (2020). Is COVID-19 the first pandemic that evolves into a panzootic? Veterinaria Italiana, 56, 7-8.
• Referans19 Griffin, B. D., Chan, M., Tailor, N., Mendoza, E. J., Leung, A., Warner, B. M., … & Kobasa, D. (2020). North American deer mice are susceptible to SARS-CoV-2. bioRxiv, 2020.2007.2025.221291. https://doi.org/10.1101/2020.
• Referans20 Griffin, B. D., Chan, M., Tailor, N., Mendoza, E. J., Leung, A., Warner, B. M., ... & Kobasa, D. (2021). SARS-CoV-2 infection and transmission in the North American deer mouse. Nature communications, 12(1), 1-10.
• Referans21 Gryseels, S., Bruyn, L. D., Gyselings, R., Calvignac-Spencer, S., Leendertz, F. H., & Leirs, H. (2020). Risk of human-to-wildlife transmission of SARS-CoV-2. Mammal Review, 51(2), 272-292. Doi: 10.1111/mam.12225.
• Referans22 Hale, V. L., Dennis, P. M., McBride, D. S., Nolting, J. M., Madden, C., Huey, D., ... & Bowman, A. S. (2022). SARS-CoV-2 infection in free-ranging white-tailed deer. Nature, 602(7897), 481-486.
• Referans23 Halfmann, P. J., Hatta, M., Chiba, S., Maemura, T., Fan, S., Takeda, M., … & Kawaoka Y. (2020). Transmission of SARS-CoV-2 in domestic cats. New England Journal of Medicine, 383, 592-594.
• Referans24 Hassan, A. O., Case, J. B., Winkler, E. S., Thackray, L. B., Kafai, N. M., Bailey, A. L, … & Diamond, M. S. (2020). A SARS-CoV-2 infection model in mice demonstrates protection by neutralizing antibodies. Cell, 182, 744-753.
• Referans25 Jemeršić, L., Lojkić, I., Krešić, N., Keros, T., Zelenika, T. A., Jurinović, L., ... & Brnić, D. (2021). Investigating the presence of SARS CoV-2 in free-living and captive animals. Pathogens, 10(6), 635.
• Referans26 Kim, Y. I., Kim, S. G., Kim, S. M., Kim, E. H., Park, S. J., Yu, K. M., … & Choi, Y. K. (2020). Infection and rapid transmission of SARS-CoV-2 in ferrets. Cell Host & Microbe, 27, 704-709.e2. https://doi.org/10.1016/j.chom.2020.03.023.
• Referans27 Konda, M., Dodda, B., Konala, V. M., Naramala, S., & Adapa, S. (2020). Potential zoonotic origins of SARS-CoV-2 and insights for preventing future pandemics through One Health approach. Cureus, 12, e8932.
• Referans28 Kumar, A., Pandey, S. N., Pareek, V., Narayan, R. K., Faiq, M. A., & Kumari, C. (2020). Predicting susceptibility for SARS-CoV-2 infection in domestic and wildlife animals using ACE2 protein sequence homology. Zoo Biology, 40(1), 79-85.
• Referans29 Lam, T., Jia, N., Zhang, Y. W., Shum, M., Jiang, J. F., Zhu, H. C., Tong, Y. G., … & Cao, W. C. (2020). Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins. Nature, 583 (7815), 282-285.
• Referans30 Lassaunière, R., Fonager, J., Rasmussen, M., Frische, A., Polacek, C., Rasmussen, T. B., ... & Fomsgaard, A. (2021). In vitro characterization of fitness and convalescent antibody neutralization of SARS-CoV-2 Cluster 5 variant emerging in mink at Danish farms. Frontiers in Microbiology, 12, 698944.
• Referans31 Liu, P., Jiang, J. Z., Wan, X. F., Hua, Y., Li, L., Zhou, J., … & Chen, J. (2020a). Are pangolins the intermediate host of the 2019 novel coronavirus (SARS-CoV-2)? PLOS Pathogens, 16(5), e1008421. Doi: 10.1371/journalppat.1008421.
• Referans32 Liu, Z., Xiao, X., Wei, X., Li, J., Yang, J., Tan, H., … & Liu, L. (2020b). Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS-CoV-2. Journal of Medical Virology, 92(6), 595-601.
• Referans33 Lu, S., Zhao, Y., Yu, W., Yang, Y., Gao, J., Wang, J., … & Peng, X. (2020). Comparison of nonhuman primates identified the suitable model for COVID-19. Signal Transduction and Targeted Therapy, 5(1), 157.
• Referans34 Luan, J., Jin, X., Lu, Y., & Zhang, L. (2020). SARS-CoV-2 spike protein favors ACE2 from Bovidae and Cricetidae. Journal of Medical Virology, 92(9), 1649-1656.
• Referans35 Mahdy MA, Younis W, Ewaida Z. (2020). An overview of SARS-CoV-2 and animal infection. Frontiers in Veterinary Scince, 7, 596391. Doi: 10.3389/fvets.2020.596391.
• Referans36 Martinez-Hernandez, F., Isaak-Delgado, A. B., Alfonso-Toledo, A., Munoz-Garcia, C. I., Villalobos, G., & Arechiga-Ceballos, N. (2020). Assessing the SARS-CoV-2 threat to wildlife: Potential risk to a broad range of mammals. Perspectives in Ecology and Conservation, 18, 223-234.
• Referans37 Meekins, D. A., Gaudreault, N. N., & Richt, J. A. (2021). Natural and experimental SARS-CoV-2 infection in domestic and wild animals. Viruses, 13(10), 1993.
• Referans38 McAloose, D., Laverack, M., Wang, L., Killian, M. L., Caserta, L. C., Yuan, F., … & Diel, D. G. (2020). From people to panthera: natural SARS-CoV-2 infection in tigers and lions at the Bronx zoo. mBio, 11(5), e02220-20. Doi: 10.1128/mBio.02220-20.
• Referans39 Monchatre-Leroy, E., Lesellier, S., Wasniewski, M., Picard-Meyer, E., Richomme, C., Boué, F., ... & Marianneau, P. (2021). Hamster and ferret experimental infection with intranasal low dose of a single strain of SARS-CoV-2. The Journal of General Virology, 102(3), 001567.
• Referans40 Munster, V. J., Feldmann, F., Williamson, B. N., van Doremalen, N., Perez-Perez, L., Schulz, J., … & de Wit E. (2020). Respiratory disease and virus shedding in rhesus macaques inoculated with SARS-CoV-2. bioRxiv. Doi: 10.1038/s41586-020-2324-7.
• Referans41 Mushi, V. (2020). The holistic way of tackling the COVID-19 pandemic: the one health approach. Tropical Medicine and Health, 48, 69. Doi: 10.1186/s41182-020-00257-0.
• Referans42 Mykytyn, A. Z., Lamers, M. M., Okba, N. M., Breugem, T. I., Schipper, D., Doel, V. D., … & Haagmans BL. (2020). Susceptibility of rabbits to SARS-CoV-2. Emerging Microbes and Infections, 10, 1-17.
• Referans43 OIE. (2020). World Organization for Animal Health. Guidelines for working free-ranging wild mammals in the era of the COVID-19 pandemic. Access date: 21.03.2021. https://www.oie.int/fileadmin/Home/eng/Our_scientific_expertise/docs/pdf/COV-19/A_WHSG_and_OIE_COVID-19_Guidelines.pdf.
• Referans44 Olival, K. J., Cryan, P. M., Amman, B. R., Baric, R. S., Blehert, D. S., Brook, C. E., … & Wang L. F. (2020). Possibility for reverse zoonotic transmission of SARS-CoV-2 to free-ranging wildlife: A case study of bats. PLoS Pathogens, 16(9), e1008758.
• Referans45 Oreshkova, N., Molenaar, R. J., Vreman, S., Harders, F., Oude Munnink, B. B., Hakze-van der Honing, R. W., … & Stegeman, A. (2020). SARS-CoV-2 infection in farmed minks, the Netherlands, April and May 2020. Eurosurveillance, 25(23), 2001005. https://doi.org/10.2807/1560-7917.ES.2020.25.23.2001005.
• Referans46 Praharaj, M. R., Garg, P., Kesarwani, V., Topno, N. A., Khan, R. I. N., Sharma, S., ... & Mohapatra, T. (2021). SARS-CoV-2 Spike Glycoprotein and ACE2 interaction reveals modulation of viral entry in wild and domestic animals. Frontiers in Medicine, 8, 775572.
• Referans47 Richard, M., Kok, A., de Meulder, D., Bestebroer, T. M., Lamers, M. M., Okba, N. M. A., … & Herfst, S. (2020). SARS-CoV-2 is transmitted via contact and via the air between ferrets. Nature Communications, 11, 3496. https://doi.org/10.1038/s41467-020-17367-2.
• Referans48 Rockx, B., Kuiken, T., Herfst, S., Bestebroer, T., Lamers, M. M., Oude Munnink, B. B., … & Haagmans, B. L. (2020). Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model. Science, 368(6494), 1012-1015.
• Referans49 Rodriguez-Morales, A. J., Bonilla-Aldana, D. K., Balbin-Ramon, G. J., Rabaan, A. A., Sah, R., Paniz-Mondolfi, A., Pagliano, P., & Esposito, S. (2020). History is repeating itself, a probable zoonotic spillover as a cause of an epidemic: the case of 2019 novel Coronavirus. Le Infezioni in Medicina, 28(1), 3-5.
• Referans50 Schlottau, K., Rissmann, M., Graaf, A., Schön, J., Sehl, J., Wylezich C, … & Beer M. (2020). SARS-CoV-2 in fruit bats, ferrets, pigs, and chickens: an experimental transmission study. The Lancet Microbe, 1, e218-e225. https://doi.org/10.1016/S2666-5247(20)30089-6.
• Referans51 Schmitt, C. A., Bergey, C. M., Jasinska, A. J., Ramensky, V., Burt, F., Svardal, H., & Turner, T. R. (2020). ACE2 and TMPRSS2 variation in savanna monkeys (Chlorocebus spp.): Potential risk for zoonotic/anthroponotic transmission of SARS-CoV-2 and a potential model for functional studies. PLoS One, 15(6), e0235106. Doi: 10.1371/journal.pone.0235106.
• Referans52 Sharun, K., Tiwari, R., Natesan, S., & Dhama, K. (2021). SARS-CoV-2 infection in farmed minks, associated zoonotic concerns, and importance of the One Health approach during the ongoing COVID-19 pandemic. Veterinary Quarterly, 41(1), 50-60.
• Referans53 Shi, J., Wen, Z., Zhong, G., Yang, H., Wang, C., Huang, B., … & Bu, Z. (2020). Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2. Science, 368, 1016-1020.
• Referans54 Sia, S. F., Yan, L. M., Chin, W. H., Fung, K., Choy, K. T., Wong, Y. L., … & Yen, H. L. (2020). Pathogenesis and transmission of SARS-CoV-2 in golden hamsters. Nature, 583, 834-838.
• Referans55 Sun, J., Zhuang, Z., Zheng, J., Li, K., Wong, L. Y., Liu, D., … & Zhao J. (2020). Generation of a broadly useful model for COVID-19 pathogenesis, vaccination, and treatment. Cell, 182, 734-743.
• Referans56 Tiwari, R., Dhama, K., Sharun, K., Yatoo, M., Malik, Y. S., Singh, R., … & Rodriguez-Morales AJ. (2020). COVID-19: animals, veterinary and zoonotic links. Veterinary Quarterly, 40(1), 169-182.
• Referans57 Valencak, T. G., Csiszar, A., Szalai, G., Podlutsky, A., Tarantini, S., Fazekas-Pongor, V., ... & Ungvari, Z. (2021). Animal reservoirs of SARS-CoV-2: calculable COVID-19 risk for older adults from animal to human transmission. GeroScience, 43(5), 2305-2320.
• Referans58 Wang, L., Mitchell, P. K., Calle, P. P., Bartlett, S. L., McAloose, D., Killian, M. L., … & Torchetti, M. K. (2020). Complete genome sequence of SARS-CoV-2 in a tiger from a U.S. zoological collection. Microbiology Resource Announcements, 9(22), e00468-20. Doi: 10.1128/MRA.00468-20.
• Referans59 Woolsey, C., Borisevich, V., Prasad, A. N., Agans, K. N., Deer, D. J., Dobias, N. S., … & Cross, R. W. (2020). Establishment of an African green monkey model for COVID-19. Nature Immunology, 22(1), 86-98.
• Referans60 Xiao, K., Zhai, J., Feng, Y., Zhou, N., Zhang, X., Zou, J. J., … & Shen, X. (2020). Isolation and characterization of 2019-nCoV-like coronavirus from Malayan Pangolins. bioRxiv. Doi: 10.1101/2020.02.17.951335.
• Referans61 Zhao, Y., Wang, J., Kuang, D., Xu, J., Yang, M., Ma, C., … & Peng, X. (2020). Susceptibility of tree shrew to SARS-CoV-2 infection. Scientific Reports, 10(1), 16007.
• Referans62 Zhou, P., Yang, X. L., Wang, X. G., Hu, B., Zhang, L., Zhang, W., … & Shi ZL. (2020). A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature, 579, 270-273.