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THE EFFECTS OF DIFFERENT PRESERVATION METHODS APPLIED DONKEY MILK SAMPLES ON SOME HEMATOLOGICAL and BIOCHEMICAL PARAMETERS in WISTAR RATS

Year 2022, Volume: 5 Issue: 2, 557 - 568, 30.09.2022
https://doi.org/10.52538/iduhes.1170340

Abstract

Çalışmanın amacını, eşek sütü örneklerine uygulanan farklı muhafaza yöntemlerinin ratlardaki bazı hematolojik [lökositler (WBC), hemoglobin (HGB), hematokrit (HCT), trombositler (PLT), eritrositler (RBC), ortalama korpüsküler hemoglobin üzerindeki etkilerinin araştırılmasıdır. (MCH), ortalama alyuvar hemoglobin konsantrasyonu (MCHC), ortalama alyuvar hacmi (MCV) ve diferansiyel WBC (lenfosit, monosit, nötrofil) sayıları] ve biyokimyasal [(serum kreatin (CREAT), alanin aminotransferaz (ALT), aspartat aminotransferaz ( AST), alkalin fosfataz (ALP), trigliseritler (TG), toplam serum proteini (TP), albümin (ALB), globulin (GLOB), üre (UREA), kan üre azotu (BUN), kolesterol (CHOL), glikoz ( Sıçanlarda GLU), kalsiyum (Ca), fosfor (P), sodyum (Na), klor (Cl), potasyum (K) ve ozmolarite (OSM)] parametreler üzerine etkileri oluşturmuştur. Bu amaçla 28 erkek Wistar albino rat; Kontrol (C; n = 7), Çiğ süt (Rm; n = 7), Pastörizasyon (Geçmiş; n = 7) ve Ultrason (Ult; n = 7) grupları olarak 4 eşit gruba ayrıldı. Kontrol grubu hariç sıçanların her birine 4 hafta boyunca Past ve Ult uygulamalı süt örnekleri (48 ml/gün oranında) verildi. Deney boyunca C grubuna ad libitum olarak sadece standart rat yemi ve içme suyu verildi. Uygulama periyodunun ardından ratlar sakrifiye edilerek hematolojik ve biyokimyasal analizler için kan örnekleri alındı. WBC düzeyleri C'ye göre en yüksek Ult grubunda tespit edildi (p < 0,05). Ayrıca LYM düzeyleri de Ult ve Rm gruplarında C grubuna göre en yüksek bulundu (p < 0,05). Ayrıca çalışmamızda diğer gruplara göre en yüksek NEU seviyeleri Ult grubunda gözlendi (p < 0,05). İlginç bir şekilde, bu çalışmada serum ALP değerleri diğer deney gruplarına (C, Ult ve Past) göre Rm grubunda en yüksek olarak tanımlanmıştır (p < 0,05). Öte yandan çalışmamızda Past grubunda serum AST değerleri C, Ult ve Rm gruplarına göre kesin olarak daha yüksekti (p < 0,05). Ayrıca çalışmamızda, Past grubunda serum Cl değerleri C grubuna göre daha yüksekti (p < 0,05). Sonuç olarak, eşek sütü örneklerine uygulanan farklı muhafaza yöntemlerinin sıçanlarda bazı hematolojik ve biyokimyasal özellikler üzerinde potansiyel etkileri olduğu görülmüştür.

References

  • Abdel-Mobdy AE, El Hussieny MS, Abdel Mobdy YE. (2021). Evaluation of Therapeutic and Protective Influences of Camel Milk Against Gamma Radiation– Induced Hematotoxicity, Hepatotoxicity and Nephrotoxicity in Albino Rats. Annals of R.S.C.B. 25(3): 7958 – 7976.
  • Abdullah SN, You KY, Hisham Khamis N, Chong CY. (2019) Modelling the Dielectric Properties of Cow's Raw Milk Under Vat Pasteurization. Progress. Electromag Res. 84: 157-166.
  • Ali MZ, Qureshi AS, Usman M, Kausar R, Ateeq MK. Comparative effect of camel milk and black seed oil in induced diabetic female albino rats. Pak Vet J, 2(2): 212.
  • Altomonte I, Salari F, Licitra RM. (2019). Donkey and human milk: Insights into their compositional similarities. Int. Dairy J. 89: 111-118 Altomonte MM, Licitra IR, Salari F. (2018). Short communication: Technological and seasonal variations of vitamin D and other nutritional components in donkey milk. J. Dairy Sci. 101: 8721–8725.
  • Awad TS, Moharram HA, Shaltout OE. Applications of Ultrasound in Analysis, Processing and Quality Control of Food: A Review. (2012). Food. Res Int. 48(2). DOI: 10.1016/j.foodres.2012.05.004.
  • Bansal B, Chen XD. (2006). A critical review of milk fouling in heat exchangers. Comp. Review Food Sci Food Safety. 5(2): 27-33. Chihara G. (1992). Immunopharmacology of lentinan, a polysaccharide isolatedfrom Lentinus edodes: its application as a host defense potentiator. Int. J Oriental Med. 17: 57-77.
  • Deeba F, Qureshi AS, Kamran M, Farooq A, et al. (2020). Short term therapeutic efficacy of camel milk Vis-À-Vis buffalo milk in Alloxan® induced diabetic rabbits. J Diabetes Metab Dis.19:915–923. https://doi.org/10.1007/s40200-020-00580-7
  • Dönmez N, Kısadere I, Balaban C, Kadiralieva N. (2014). Effects of traditional homemade koumiss on some hematological and biochemical characteristics in sedentary men exposed to exercise, Biotech Histochem. 89:(8) 558-563, DOI: 10.3109/10520295.2014.91542.
  • Fisberg M, Horta PM, Santos LC, Amici MR, et al. (2010). Modification of constituents and exploration of functional properties of goat’s milk: effects on the health and nutritional status of preschoolers. J. Med Medical Sci. 1(9) :412-417.
  • Khalid AG, Al-Adhadh AJ. (2014). The protective role of camel's milk on some hematological parameters of male rats infected with gastric ulcer. World. J Pharm Sci. 2(11): 1465-1468.
  • Kısadere I, Donmez N, Omurzakova N. (2019). Serum biochemical reference values of Kyrgyz donkeys (Equus asinus). Comp Clinic Pathol. 28: 817–823.
  • Lu DL, Zhang DF, Liu PL, Dong ML. (2006). The nutrition value and exploitation of donkey milk. J. Dairy Sci. Technol. 29: 11-18. Mao X, Gu J, Sun Y, Xu S, et al. (2009). Anti-proliferative and anti-tumour effect of active components in donkey milk on A549 human lung cancer cells. Int. Dairy J. 19(11):703-708.
  • Martini M, Altomonte I, Tricò D, Lapenta R, Salari F. (2021). Current Knowledge on Functionality and Potential Therapeutic Uses of Donkey Milk. Animals. 11: 1382. https://doi.org/10.3390/ani11051382.
  • Miao J, Lang C, Kang Z, Zhu H, et al. (2016). Oral administration of fermented milk supplemented with synbiotics can influence the physiological condition of Wistar rats in a dose-sensitive and sex-specific manner. Biosci. Microb Food Health. 35 (2): 89-96. Pilla R, Dapra V, Zecconi A, Piccinini R. (2010). Hygienic and health characteristics of donkey milk during a follow-up study. J. Dairy Res. 77(4): 392.
  • Roth‐Walter F, Berin MC, Arnaboldi P, Escalante CR, et al. (2008). Pasteurization of milk proteins promotes allergic sensitization by enhancing uptake through Peyer's patches. Allergy. 63(7): 882-890.
  • Shershenkov B, Suchkova E. (2015). Upgrading the technology of functional dairy products by means of fermentation process ultrasonic intensification. Agronomy. Res. 13(4):1074-1085.
  • Shoukrallahi B, Manrouf M, Hamid Amonlou. (2013). The Effect of Enriched Milk with Selenium and Vitamin Eon Growth Rate, Hematology, Some Blood BiochemicalFactors, and Immunoglobulins of Newborn Goat Kids. Biol. Trace. Elem Res. 153:184–190. DOI: 10.1007/s12011-013-9685-9.
  • Singh P, Pandey RK, Paswan VK, Yadav SP, et al. (2019). Effect of supplementation of L. plantarum and L. casei based probiotic milk powder on hematology, blood biochemistry and lipid profile of Charles Foster rats. Indian. J. Anim. Res. 53 (3): 332-335. Soria AC, Villamiel M, Villamiel M. (2010). Effect of ultrasound on the technological properties and bioactivity of food: A review. Trends. Food Sci Technol. 21(7):323-331.
  • Trinchese G, Cavaliere G, De Filippo C, Aceto S, et al. (2018). Human Milk and Donkey Milk, Compared to Cow Milk, Reduce Inflammatory Mediators and Modulate Glucose and Lipid Metabolism, Acting on Mitochondrial Function and Oleylethanolamide Levels in Rat Skeletal Muscle. Front. Physiol. 30: 9-32. doi: 10.3389/fphys.2018.00032.
  • Xu M, Wei L, Dai Z, Zhang Y, et al. (2015). Effects of goat milk–based formula on development in weaned rats. Food Nutr Res. 59:1, 28610, DOI: 10.3402/fnr.v59.28610.

Eşek sütü örneklerine uygulanan farklı muhafaza yöntemlerinin Wistar sıçanlarında bazı hematolojik ve biyokimyasal parametreler üzerine etkileri

Year 2022, Volume: 5 Issue: 2, 557 - 568, 30.09.2022
https://doi.org/10.52538/iduhes.1170340

Abstract

Çalışmanın amacını, eşek sütü örneklerine uygulanan farklı muhafaza yöntemlerinin ratlardaki bazı hematolojik [lökositler (WBC), hemoglobin (HGB), hematokrit (HCT), trombositler (PLT), eritrositler (RBC), ortalama korpüsküler hemoglobin üzerindeki etkilerinin araştırılmasıdır. (MCH), ortalama alyuvar hemoglobin konsantrasyonu (MCHC), ortalama alyuvar hacmi (MCV) ve diferansiyel WBC (lenfosit, monosit, nötrofil) sayıları] ve biyokimyasal [(serum kreatin (CREAT), alanin aminotransferaz (ALT), aspartat aminotransferaz ( AST), alkalin fosfataz (ALP), trigliseritler (TG), toplam serum proteini (TP), albümin (ALB), globulin (GLOB), üre (UREA), kan üre azotu (BUN), kolesterol (CHOL), glikoz ( Sıçanlarda GLU), kalsiyum (Ca), fosfor (P), sodyum (Na), klor (Cl), potasyum (K) ve ozmolarite (OSM)] parametreler üzerine etkileri oluşturmuştur. Bu amaçla 28 erkek Wistar albino rat; Kontrol (C; n = 7), Çiğ süt (Rm; n = 7), Pastörizasyon (Geçmiş; n = 7) ve Ultrason (Ult; n = 7) grupları olarak 4 eşit gruba ayrıldı. Kontrol grubu hariç sıçanların her birine 4 hafta boyunca Past ve Ult uygulamalı süt örnekleri (48 ml/gün oranında) verildi. Deney boyunca C grubuna ad libitum olarak sadece standart rat yemi ve içme suyu verildi. Uygulama periyodunun ardından ratlar sakrifiye edilerek hematolojik ve biyokimyasal analizler için kan örnekleri alındı. WBC düzeyleri C'ye göre en yüksek Ult grubunda tespit edildi (p < 0,05). Ayrıca LYM düzeyleri de Ult ve Rm gruplarında C grubuna göre en yüksek bulundu (p < 0,05). Ayrıca çalışmamızda diğer gruplara göre en yüksek NEU seviyeleri Ult grubunda gözlendi (p < 0,05). İlginç bir şekilde, bu çalışmada serum ALP değerleri diğer deney gruplarına (C, Ult ve Past) göre Rm grubunda en yüksek olarak tanımlanmıştır (p < 0,05). Öte yandan çalışmamızda Past grubunda serum AST değerleri C, Ult ve Rm gruplarına göre kesin olarak daha yüksekti (p < 0,05). Ayrıca çalışmamızda, Past grubunda serum Cl değerleri C grubuna göre daha yüksekti (p < 0,05). Sonuç olarak, eşek sütü örneklerine uygulanan farklı muhafaza yöntemlerinin sıçanlarda bazı hematolojik ve biyokimyasal özellikler üzerinde potansiyel etkileri olduğu görülmüştür.

References

  • Abdel-Mobdy AE, El Hussieny MS, Abdel Mobdy YE. (2021). Evaluation of Therapeutic and Protective Influences of Camel Milk Against Gamma Radiation– Induced Hematotoxicity, Hepatotoxicity and Nephrotoxicity in Albino Rats. Annals of R.S.C.B. 25(3): 7958 – 7976.
  • Abdullah SN, You KY, Hisham Khamis N, Chong CY. (2019) Modelling the Dielectric Properties of Cow's Raw Milk Under Vat Pasteurization. Progress. Electromag Res. 84: 157-166.
  • Ali MZ, Qureshi AS, Usman M, Kausar R, Ateeq MK. Comparative effect of camel milk and black seed oil in induced diabetic female albino rats. Pak Vet J, 2(2): 212.
  • Altomonte I, Salari F, Licitra RM. (2019). Donkey and human milk: Insights into their compositional similarities. Int. Dairy J. 89: 111-118 Altomonte MM, Licitra IR, Salari F. (2018). Short communication: Technological and seasonal variations of vitamin D and other nutritional components in donkey milk. J. Dairy Sci. 101: 8721–8725.
  • Awad TS, Moharram HA, Shaltout OE. Applications of Ultrasound in Analysis, Processing and Quality Control of Food: A Review. (2012). Food. Res Int. 48(2). DOI: 10.1016/j.foodres.2012.05.004.
  • Bansal B, Chen XD. (2006). A critical review of milk fouling in heat exchangers. Comp. Review Food Sci Food Safety. 5(2): 27-33. Chihara G. (1992). Immunopharmacology of lentinan, a polysaccharide isolatedfrom Lentinus edodes: its application as a host defense potentiator. Int. J Oriental Med. 17: 57-77.
  • Deeba F, Qureshi AS, Kamran M, Farooq A, et al. (2020). Short term therapeutic efficacy of camel milk Vis-À-Vis buffalo milk in Alloxan® induced diabetic rabbits. J Diabetes Metab Dis.19:915–923. https://doi.org/10.1007/s40200-020-00580-7
  • Dönmez N, Kısadere I, Balaban C, Kadiralieva N. (2014). Effects of traditional homemade koumiss on some hematological and biochemical characteristics in sedentary men exposed to exercise, Biotech Histochem. 89:(8) 558-563, DOI: 10.3109/10520295.2014.91542.
  • Fisberg M, Horta PM, Santos LC, Amici MR, et al. (2010). Modification of constituents and exploration of functional properties of goat’s milk: effects on the health and nutritional status of preschoolers. J. Med Medical Sci. 1(9) :412-417.
  • Khalid AG, Al-Adhadh AJ. (2014). The protective role of camel's milk on some hematological parameters of male rats infected with gastric ulcer. World. J Pharm Sci. 2(11): 1465-1468.
  • Kısadere I, Donmez N, Omurzakova N. (2019). Serum biochemical reference values of Kyrgyz donkeys (Equus asinus). Comp Clinic Pathol. 28: 817–823.
  • Lu DL, Zhang DF, Liu PL, Dong ML. (2006). The nutrition value and exploitation of donkey milk. J. Dairy Sci. Technol. 29: 11-18. Mao X, Gu J, Sun Y, Xu S, et al. (2009). Anti-proliferative and anti-tumour effect of active components in donkey milk on A549 human lung cancer cells. Int. Dairy J. 19(11):703-708.
  • Martini M, Altomonte I, Tricò D, Lapenta R, Salari F. (2021). Current Knowledge on Functionality and Potential Therapeutic Uses of Donkey Milk. Animals. 11: 1382. https://doi.org/10.3390/ani11051382.
  • Miao J, Lang C, Kang Z, Zhu H, et al. (2016). Oral administration of fermented milk supplemented with synbiotics can influence the physiological condition of Wistar rats in a dose-sensitive and sex-specific manner. Biosci. Microb Food Health. 35 (2): 89-96. Pilla R, Dapra V, Zecconi A, Piccinini R. (2010). Hygienic and health characteristics of donkey milk during a follow-up study. J. Dairy Res. 77(4): 392.
  • Roth‐Walter F, Berin MC, Arnaboldi P, Escalante CR, et al. (2008). Pasteurization of milk proteins promotes allergic sensitization by enhancing uptake through Peyer's patches. Allergy. 63(7): 882-890.
  • Shershenkov B, Suchkova E. (2015). Upgrading the technology of functional dairy products by means of fermentation process ultrasonic intensification. Agronomy. Res. 13(4):1074-1085.
  • Shoukrallahi B, Manrouf M, Hamid Amonlou. (2013). The Effect of Enriched Milk with Selenium and Vitamin Eon Growth Rate, Hematology, Some Blood BiochemicalFactors, and Immunoglobulins of Newborn Goat Kids. Biol. Trace. Elem Res. 153:184–190. DOI: 10.1007/s12011-013-9685-9.
  • Singh P, Pandey RK, Paswan VK, Yadav SP, et al. (2019). Effect of supplementation of L. plantarum and L. casei based probiotic milk powder on hematology, blood biochemistry and lipid profile of Charles Foster rats. Indian. J. Anim. Res. 53 (3): 332-335. Soria AC, Villamiel M, Villamiel M. (2010). Effect of ultrasound on the technological properties and bioactivity of food: A review. Trends. Food Sci Technol. 21(7):323-331.
  • Trinchese G, Cavaliere G, De Filippo C, Aceto S, et al. (2018). Human Milk and Donkey Milk, Compared to Cow Milk, Reduce Inflammatory Mediators and Modulate Glucose and Lipid Metabolism, Acting on Mitochondrial Function and Oleylethanolamide Levels in Rat Skeletal Muscle. Front. Physiol. 30: 9-32. doi: 10.3389/fphys.2018.00032.
  • Xu M, Wei L, Dai Z, Zhang Y, et al. (2015). Effects of goat milk–based formula on development in weaned rats. Food Nutr Res. 59:1, 28610, DOI: 10.3402/fnr.v59.28610.
There are 20 citations in total.

Details

Primary Language English
Subjects Veterinary Surgery
Journal Section Articles
Authors

İhsan Kısadere 0000-0003-0732-0464

Hakan Tavşanlı 0000-0002-5124-3702

Mehmet Faruk Aydın 0000-0002-6099-492X

Publication Date September 30, 2022
Submission Date September 2, 2022
Published in Issue Year 2022 Volume: 5 Issue: 2

Cite

APA Kısadere, İ., Tavşanlı, H., & Aydın, M. F. (2022). THE EFFECTS OF DIFFERENT PRESERVATION METHODS APPLIED DONKEY MILK SAMPLES ON SOME HEMATOLOGICAL and BIOCHEMICAL PARAMETERS in WISTAR RATS. Izmir Democracy University Health Sciences Journal, 5(2), 557-568. https://doi.org/10.52538/iduhes.1170340

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