Palyatif Bakımda Kanserli Hastalarda Demir Eksikliği Anemisi

Year 2023, Volume: 6 Issue: 2, 337 - 347, 30.09.2023

Orkun Sarıçam , Gülhan Sarıçam

https://doi.org/10.52538/iduhes.1277754

Abstract

Bu çalışmada amacımız, kanserli hastaların anemi derecesi ile metastaz, performans, beslenme durumu gibi etkenleri karşılaştırarak prognoza etkisini araştırmaktır.Bu çalışmaya palyatif bakımda (PB) izlenen kanserli 189 hasta dahil edildi. Hastalar kanser tanılarına göre sınıflandırıldı, demografik özellikleri, anemi paneli, kemoterapi, metastaz, performans durumu, yatış süreleri ve çıkış durumları kayıt edilerek gruplar arasında karşılaştırıldı. PB’da izlediğimiz kanserli hastaların %85.7’sinde anemi ve %88.4’ ünde metastaz vardı. Anemisi şiddetli olanlarda Eastern Cooperative Oncology Group Scale (ECOG) performans değerleri düşük, C-reaktif protein (CRP) düzeyleri diğer gruplardan anlamlı derecede yüksek bulundu. (p=0,045, p=0,000). Anemisi olmayanların Glaskow Koma Skalaları (GKS), orta derecede anemisi olanlardan anlamlı derecede daha yüksek bulundu. (p=0,049) PB’da izlediğimiz ileri evre kanserli hastalarda, düşük ECOG, yüksek GKS ve CRP değerleri gibi kötü prognostik kriterler ile aneminin şiddeti arasında ilişki olduğunu gösterdik. Kanserli hastalarda, aneminin erken değerlerilmesi, yeterli beslenme ve demir tedavilerin verilmesi sağlanmalı, sağkalım ve prognoz üzerindeki etkileri daha geniş çaplı çalışmalarla araştırılmalıdır.

Keywords

Anemi, Kanser, Palyatif Bakım

Supporting Institution

yok

Iron Deficiency Anemia in Cancer Patients in Palliative Care

Abstract

In this study, we aimed to investigate the effects of anemia on the prognosis by comparing the severity of anemia with several prognostic factors including metastases, functional performance, and the feeding status of cancer patients.This study included 189 cancer patients, who received treatment in the palliative care unit (PCU). Demographic characteristics of the patients, anemia test panel results, chemotherapy, the status of metastases, functional performance, the length of hospital stay, and the status at discharge were recorded and compared between the study groups. Of the cancer patients in PCU, 85.7% had anemia and 88.4% had metastases. In patients with severe anemia, the Eastern Cooperative Oncology Group Scale (ECOG) performance scores were lower and C-reactive protein (CRP) levels were significantly higher compared to the other patients in other groups (p=0.045, p=0.000). Glasgow Coma Scales (GCS) were found to be significantly lower in patients with moderate anemia than those without anemia. (p=0.049) We have shown that there is a correlation between the severity of anemia and poor prognostic criteria including low ECOG, GCS scores and high CRP levels in advanced cancer patients we treated in PCU. The early assessment of anemia and the adequate intake of nutrients along with iron supplements should be ensured in cancer patients during the disease course.

Keywords

Anemia, Cancer, Palliative Care

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