A novel nicotinoyl thiourea manganese complex: synthesis, characterization, and biological activity studies

Fatma Betül Özgeriş; Merve Yıldırım; Arzu Görmez; Bünyamin Özgeriş

doi:10.32571/ijct.940169

Research Article

Year 2021, Volume: 5 Issue: 2, 83 - 90, 31.12.2021

Fatma Betül Özgeriş , Merve Yıldırım , Arzu Görmez , Bünyamin Özgeriş

https://doi.org/10.32571/ijct.940169

Cited By: 1

Abstract

References

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13. Ozgeris, B. J. Antibiot. 2021, 74 (4), 233-243.
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32. Özgeriş, B. Russ. J. Org. Chem. 2021, 57 (3), 422-429.
33. Zhong, Z.; Xing, R.; Liu, S.; Wang, L.; Cai, S.; Li, P. Carbohydr. Res. 2008, 343 (3), 566-570.
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35. Venkatesh, P.; Pandeya, S. N. Int. J. Chemtech Res. 2009, 1 (3), 733-741.
36. Mojarrab, M.; Soltani, R.; Aliabadi, A. Jundishapur J. Nat. Pharm. Prod. 2013, 8 (3), 125-130.
37. Chen, W. J.; Sun, S. F.; Cao, W.; Liang, Y.; Song, J. R. J. Mol. Struct. 2009, 918 (1-3), 194-197.

A novel nicotinoyl thiourea manganese complex: synthesis, characterization, and biological activity studies

Year 2021, Volume: 5 Issue: 2, 83 - 90, 31.12.2021

Fatma Betül Özgeriş , Merve Yıldırım , Arzu Görmez , Bünyamin Özgeriş

https://doi.org/10.32571/ijct.940169

Cited By: 1

Abstract

Bu çalışmada daha önce grubumuz tarafından sentezlenen nikotinoil tiyoüre, nikotinik asit ve 3,5-dimetoksi anilinden başlanarak sentezlenmiştir. Elde edilen ürün Mangan (II) asetat tetrahidrat ile tepkimeye sokularak 1:1 metal-ligand oranıyla nikotinoyil tiyoüre mangan kompleksi sentezlenmiştir. Sentezlenen yeni metal kompleksinin kimyasal yapısı FTIR, HRMS, XRD ve elementel analiz ile karakterize edilmiştir. Çalışmanın ikinci bölümünde sentezlenen metal kompleksin antibakteriyel ve antioksidan aktiviteleri araştırılmıştır. Elde edilen sonuçlara göre metal kompleksi herhangi bir antibakteriyel aktivite göstermemiştir. Bununla birlikte metal kompleksi DPPH, ABTS ve kuprak metotlarında standart antioksidanlara göre güçlü veya eşit potansiyelli antioksidan özellikler sergilemiştir. Bu nedenle, metal kompleksi gıdanın korunması gibi aşamalarda ve oksidatif stres ile ilişkili birçok hastalığın tedavisinde bir antioksidan ajan olarak değerlendirilebilir.

Keywords

Thiourea, Manganese, Metal Complex, Antibacterial Activity, Antioxidant Properties.

References

1. Schroeder, D. C. Chem. Rev. 1955, 55 (1), 181-228.
2. Murru, S.; Singh, C. B.; Kavala, V.; Patel, B. K. Tetrahedron 2008, 64 (8), 1931-1942.
3. Saeed, A.; Flörke, U.; Erben, M. F. J. Sulphur Chem. 2014, 35 (3), 318-355.
4. Duan, L. P.; Xue, J.; Xu, L. L.; Zhang, H. B. Molecules 2010, 15 (10), 6941-6947.
5. Cunha, S.; Macedo, F. C.; Costa, G. A. N.; Rodrigues, M. T.; Verde, R. B. V.; de Souza Neta, L. C.; Vencato, I.; Lariucci, C.; Sá, F. P. Monatsh. Chem. 2007, 138 (5), 511-516.
6. Wyles, D. L.; Kaihara, K. A.; Schooley, R. T. Antimicrob. Agents Chemother. 2008, 52 (5), 1862-1864.
7. Brito, T. O.; Souza, A. X.; Mota, Y. C. C.; Morais, V. S. S.; de Souza, L. T.; de Fatima, A.; Macedo, F.; Modolo, L. V. RSC Adv. 2015, 5 (55), 44507-44515.
8. Lim, H. D.; Istyastono, E. P.; van de Stolpe, A.; Romeo, G.; Gobbi, S.; Schepers, M.; Lahaye, R.; Menge, W.; Zuiderveld, O. P.; Jongejan, A.; Smits, R. A.; Bakker, R. A.; Haaksma, E. E. J.; Leurs, R.; de Esch, I. J. P. Bioorg. Med. Chem. 2009, 17 (11), 3987-3994.
9. Elhusseiny, A. F.; Eldissouky, A.; Al-Hamza, A. M.; Hassan, H. J. Mol. Struct. 2015, 1100, 530-545.
10. Ozpozan, N.; Arslan, H.; Ozpozan, T.; Merdivan, M.; Kulcu, N. J. Therm. Anal. Calorim. 2000, 61 (3), 955-965.
11. Ozpozan, N.; Arslan, H.; Ozpozan, T.; Ozdes, N.; Kulcu, N. Thermochim. Acta 2000, 343 (1-2), 127-133.
12. Ozpozan, N.; Ozpozan, T.; Arslan, H.; Karipcin, F.; Kulcu, N. Thermochim. Acta 1999, 336 (1-2), 97-103.
13. Ozgeris, B. J. Antibiot. 2021, 74 (4), 233-243.
14. Tumer, F.; Goksu, S.; Secen, H. Russ Chem Bull. 2005, 54 (10), 2466-2467.
15. Xue, S.-j.; Guan, Q. Chinese J. Org. Chem. 2002, 22 (9), 646-650.
16. CLSI, Performance Standards for Antimicrobial Susceptibility Testing. 27 ed.; Clinical and Laboratory Standards Institute,: Wayne, PA, 2017.
17. Gormez, A.; Bozari, S.; Yanmis, D.; Gulluce, M.; Sahin, F.; Agar, G. Pol. J. Microbiol. 2015, 64 (2), 121-127.
18. Zgoda, J. R.; Porter, J. R. Pharm. Biol. 2001, 39 (3), 221-225.
19. Gülçin, İ. Life Sci. 2006, 78 (8), 803-811.
20. Gülçin, İ. Toxicology 2006, 217 (2), 213-220.
21. Re, R.; Pellegrini, N.; Proteggente, A.; Pannala, A.; Yang, M.; Rice-Evans, C. Free Radic. Biol. Med. 1999, 26 (9), 1231-1237.
22. Gülçin, İ.; Mshvildadze, V.; Gepdiremen, A.; Elias, R. Phytomedicine 2006, 13 (5), 343-351.
23. Aksu, K.; Ozgeris, B.; Taslimi, P.; Naderi, A.; Gulcin, I.; Goksu, S. Arch. Pharm. (Weinheim) 2016, 349 (12), 944-954.
24. Tohma, H. S.; Gulçin, I. Int. J. Food Prop. 2010, 13 (4), 657-671.
25. Nozha, S. G.; Morgan, S. M.; Ahmed, S. E. A.; El-Mogazy, M. A.; Diab, M. A.; El-Sonbati, A. Z.; Abou-Dobara, M. I. J. Mol. Struct. 2020, 129525.
26. Selvakumaran, N.; Bhuvanesh, N. S. P.; Karvembu, R. Dalton Trans. 2014, 43 (43), 16395-16410.
27. Yeşilkaynak, T. J. Turkish Chem. Soc. Sect. Chem. 2016, 3 (3), 1-14.
28. Cullity, B. D., Elements of X-Ray Diffraction. 2nd Edition ed.; Addison-Wesley Publishing Company, Inc. : Reading, MA, 1978.
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30. Obradovic, D.; Nikolic, S.; Milenkovic, I.; Milenkovic, M.; Jovanovic, P.; Savic, V.; Roller, A.; Crnogorac, M. D.; Stanojkovic, T.; Grguric-Sipka, S. J. Inorg. Biochem. 2020, 210.
31. Altaf, A. A.; Shahzad, A.; Gul, Z.; Rasool, N.; Badshah, A.; Lal, B.; Khan, E. J. Drug Des.Med. Chem. (JDDMC) 2015, 1 (1), 1-11.
32. Özgeriş, B. Russ. J. Org. Chem. 2021, 57 (3), 422-429.
33. Zhong, Z.; Xing, R.; Liu, S.; Wang, L.; Cai, S.; Li, P. Carbohydr. Res. 2008, 343 (3), 566-570.
34. Ngaini, Z.; Arif, M. A. M.; Hussain, H.; Mei, E. S.; Tang, D.; Kamaluddin, D. H. A. Phosphorus Sulfur Silicon Relat. Elem. 2012, 187 (1), 1-7.
35. Venkatesh, P.; Pandeya, S. N. Int. J. Chemtech Res. 2009, 1 (3), 733-741.
36. Mojarrab, M.; Soltani, R.; Aliabadi, A. Jundishapur J. Nat. Pharm. Prod. 2013, 8 (3), 125-130.
37. Chen, W. J.; Sun, S. F.; Cao, W.; Liang, Y.; Song, J. R. J. Mol. Struct. 2009, 918 (1-3), 194-197.

There are 37 citations in total.

Details

Primary Language	English
Subjects	Chemical Engineering
Journal Section	Research Articles
Authors	Fatma Betül Özgeriş 0000-0002-4568-5782 Merve Yıldırım 0000-0002-9494-2896 Arzu Görmez 0000-0003-3246-1824 Bünyamin Özgeriş 0000-0002-3783-6501
Publication Date	December 31, 2021
Published in Issue	Year 2021 Volume: 5 Issue: 2

Cite

APA	Özgeriş, F. B., Yıldırım, M., Görmez, A., Özgeriş, B. (2021). A novel nicotinoyl thiourea manganese complex: synthesis, characterization, and biological activity studies. International Journal of Chemistry and Technology, 5(2), 83-90. https://doi.org/10.32571/ijct.940169
AMA	Özgeriş FB, Yıldırım M, Görmez A, Özgeriş B. A novel nicotinoyl thiourea manganese complex: synthesis, characterization, and biological activity studies. Int. J. Chem. Technol. December 2021;5(2):83-90. doi:10.32571/ijct.940169
Chicago	Özgeriş, Fatma Betül, Merve Yıldırım, Arzu Görmez, and Bünyamin Özgeriş. “A Novel Nicotinoyl Thiourea Manganese Complex: Synthesis, Characterization, and Biological Activity Studies”. International Journal of Chemistry and Technology 5, no. 2 (December 2021): 83-90. https://doi.org/10.32571/ijct.940169.
EndNote	Özgeriş FB, Yıldırım M, Görmez A, Özgeriş B (December 1, 2021) A novel nicotinoyl thiourea manganese complex: synthesis, characterization, and biological activity studies. International Journal of Chemistry and Technology 5 2 83–90.
IEEE	F. B. Özgeriş, M. Yıldırım, A. Görmez, and B. Özgeriş, “A novel nicotinoyl thiourea manganese complex: synthesis, characterization, and biological activity studies”, Int. J. Chem. Technol., vol. 5, no. 2, pp. 83–90, 2021, doi: 10.32571/ijct.940169.
ISNAD	Özgeriş, Fatma Betül et al. “A Novel Nicotinoyl Thiourea Manganese Complex: Synthesis, Characterization, and Biological Activity Studies”. International Journal of Chemistry and Technology 5/2 (December 2021), 83-90. https://doi.org/10.32571/ijct.940169.
JAMA	Özgeriş FB, Yıldırım M, Görmez A, Özgeriş B. A novel nicotinoyl thiourea manganese complex: synthesis, characterization, and biological activity studies. Int. J. Chem. Technol. 2021;5:83–90.
MLA	Özgeriş, Fatma Betül et al. “A Novel Nicotinoyl Thiourea Manganese Complex: Synthesis, Characterization, and Biological Activity Studies”. International Journal of Chemistry and Technology, vol. 5, no. 2, 2021, pp. 83-90, doi:10.32571/ijct.940169.
Vancouver	Özgeriş FB, Yıldırım M, Görmez A, Özgeriş B. A novel nicotinoyl thiourea manganese complex: synthesis, characterization, and biological activity studies. Int. J. Chem. Technol. 2021;5(2):83-90.

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