Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)

Year 2019, Volume: 6 Issue: 4, 317 - 322, 15.01.2020

Falah Saleh Mohammed , Mustafa Pehlivan , Mustafa Sevindik

https://doi.org/10.21448/ijsm.581500

Cited By: 13

Abstract

In
this study, antioxidant, antibacterial and antifungal
activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq)
were determined. Ethanol, methanol and dichloromethane extracts of the fruit
part of plant were obtained. Antioxidant potential was determined with TAS and
TOS kits using ethanol extracts. Antibacterial and antifungal activity were
determined using agar dilution method. Antibacterial activity was determined
against 6 bacterial strains (Staphylococcus aureus, S. aureus MRSA, Enterococcus
faecalis, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter
baumannii). Antifungal activity was determined against Candida albicans,
C. krusei and C. glabrata. As a result of the studies, it was
determined that plant extracts have high antioxidant activity. It was also
found to be effective against bacteria at 25-400 µg/mL concentrations.  Plant extracts were found to be more
effective against gram negative bacteria. It was found to be effective against Candida
species at 400-800 µg/mL concentrations. As a result, it was determined that
the fruit parts of plant could be a natural antioxidant and antibacterial
source.

Keywords

Antioxidant, Antibacterial, Antifungal, Medicinal Plants, Silybum marianum

Antioxidant, Antibacterial and Antifungal Activities of Different Extracts of Silybum marianum Collected from Duhok (Iraq)

Abstract

In this study, antioxidant, antibacterial and antifungal activities of Silybum marianum (L.) Gaertn. collected from Duhok (Iraq) were determined. Ethanol, methanol and dichloromethane extracts of the fruit part of plant were obtained. Antioxidant potential was determined with TAS and TOS kits using ethanol extracts. Antibacterial and antifungal activity were determined using agar dilution method. Antibacterial activity was determined against 6 bacterial strains (Staphylococcus aureus, S. aureus MRSA, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Acinetobacter baumannii). Antifungal activity was determined against Candida albicans, C. krusei and C. glabrata. As a result of the studies, it was determined that plant extracts have high antioxidant activity. It was also found to be effective against bacteria at 25-400 µg/mL concentrations. Plant extracts were found to be more effective against gram negative bacteria. It was found to be effective against Candida species at 400-800 µg/mL concentrations. As a result, it was determined that the fruit parts of plant could be a natural antioxidant and antibacterial source.

Keywords

Antioxidant, Antibacterial, Antifungal, Medicinal Plants, Silybum marianum

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