The relationship between age and mortality and morbidity of patients diagnosed with breast cancer: a retrospective clinical study

Year 2023, , 177 - 180, 30.12.2023

M. Burak Dal , Muhyittin Temiz

https://doi.org/10.17944/interdiscip.1379579

Abstract

Objective: Breast cancer, the most common malignancy among women, is a universally challenging health problem. It is a known fact that the incidence of breast cancer increases with age. In addition, mortality and morbidity increase with age. For now, it does not seem possible to reduce the incidence of breast cancer but it is possible to limit deaths caused by it. Patients are encouraged to get early diagnosis and age-appropriate screening tests. Because regular screening and early diagnosis are very important in improving breast cancer outcomes. Factors such as age, hormonal status and genetics are associated with the incidence of breast cancer. In this study, we aimed to contribute to the literature by examining age-related mortality and morbidity of breast cancer.

Method: This study was carried out at a University Hospital. The sample consisted of 214 women between 01.09.2018/01.09.2022 diagnosed with breast cancer, aged 30 to 80 years.

Results: The mean age of women was 51.9 ± 7.6 years, with 52.8% being <50 years. Breast-conserving surgery was performed on 56.5% of the total participants (n=121). In our series, deaths due to breast cancer are less than 1% under the age of 50 and over 3% in those over the age of 50.

Conclusion: Education campaigns should focus on increasing breast cancer awareness among young women, highlighting the importance of early detection and regular screenings. Each patient should receive a tailored treatment plan that considers their age, tumor characteristics, fertility preservation preferences, and long-term health goals.

Keywords

Breast Cancer, Survival, Incidence, Surgery

References

• Jackson E B, Gondara L, Speers C et al. Does age affect outcome with breast cancer? The Breast 70 (2023) 25-31. https://doi.org/10.1016/j.breast.2023.06.001
• Pardo S A, Pérez E M R, Castañeda N C et al. Quality of Life in Breast Cancer Survivors in Relation to Age, Type of Surgery and Length of Time since First Treatment Int. J. Environ. Res. Public Health 2022, 19, 16229. https://doi.org/10.3390/ijerph192316229
• Zheng, Yadi, et al. “Use of breast cancer risk factors to identify risk-adapted starting age of screening in China.” JAMA network open 5.11 (2022): e2241441-e2241441. https://doi.org/10.1001/jamanetworkopen.2022.41441
• Arinkan S A, Gunacti M Factors influencing age at natural menopause J. Obstet. Gynaecol. Res. Vol. 47, No. 3: 913-920, March 2021 https://doi.org/10.1111/jog.14614
• Daly M B, Rosenthal E, Cummings S et al. The association between age at breast cancer diagnosis and prevalence of pathogenic variants Breast Cancer Research and Treatment (2023) 199:617-626. https://doi.org/10.1007/s10549-023-06946-8
• Miller K, Gannon M R, Medina J et al. The Association Between Survival and Receipt of Post-mastectomy Radiotherapy According to Age at Diagnosis Among Women with Early Invasive Breast Cancer: A Population-Based Cohort Study Clinical Oncology 35 (2023) e265ee277. https://doi.org/10.1016/j.clon.2023.01.008
• Guliyeva G, Huayllani M T, Boczar D et al. Age as a risk factor for breast cancer-related lymphedema: a systematic review Journal of Cancer Survivorship (2023) 17:246-253 https://doi.org/10.1007/s11764-021-00994-z.