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Factors Associated with Post-COVID Syndrome Three Months After COVID-19

Year 2024, , 41 - 47, 02.09.2024
https://doi.org/10.17944/interdiscip.1412206

Abstract

Objective: Post-COVID Syndrome has been defined as a syndrome with chronic fatigue and psychiatric problems continue after COVID-19. In this study, it was aimed to evaluate patients' health-related quality of life standards 3 months after COVID-19 diagnosis.
Method: In this study, the psychosocial status and quality of life standards of patients, who were older than 18 years old and followed up due to COVID-19 in the outpatient clinic, ward, or intensive care unit of a university hospital, were assesed by the short form-36 scoring system.
Results: Of 67 patients, 57 were followed up and treated at home, nine were admitted to the ward, and one was admitted to the the intensive care unit. Short form-36 test scores of women patients, patients aged over 65, had at least one comorbid disease, and inpatient treatments during acute infection were found to be statistically significantly lower.
Conclusion: Gender, advanced age, presence of comorbidity, and history of hospitalization were determined as risk factors for Post-COVID Syndrome.

Ethical Statement

The study protocol was initiated with the approval of the ethics committee of a university hospital at the meeting numbered 143 on 20.10.2021 with the decision number 20.

References

  • COVID-19. JAMA. 2020;324(6):603-605. https://doi.org/10.1001/jama.2020.12603
  • Moldofsky H, Patcai J. Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study. BMC Neurol. 2011;11:37. https://doi.org/10.1186/1471-2377-11-37
  • Disease Manifestations and Complications: CDC & IDSA 2022: Post COVID/Long COVID [cited 2022 04.06.2020]. https://www.idsociety.org/covid-19-real-time-learning-network/disease-manifestations--complications/post-covid-syndrome.
  • Halpin SJ, McIvor C, Whyatt G, et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation. J Med Virol. 2021;93(2):1013-22. https://doi.org/10.1002/jmv.26368
  • Kamal M, Abo Omirah M, Hussein A, Saeed H. Assessment and characterisation of post-COVID-19 manifestations. Int J Clin Pract. 2021;75(3):e13746. https://doi.org/10.1111/ijcp.13746
  • Han Q, Zheng B, Daines L, Sheikh A. Long-Term Sequelae of COVID-19: A Systematic Review and Meta-Analysis of One-Year Follow-Up Studies on Post-COVID Symptoms. Pathogens. 2022;11(2):269. https://doi.org/10.3390/pathogens11020269
  • Huang L, Yao Q, Gu X, et al. 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study. Lancet. 2021;398(10302):747-58. https://doi.org/10.1016/S0140-6736(21)01755-4
  • Su Y, Yuan D, Chen DG, et al. Multiple early factors anticipate post-acute COVID-19 sequelae. Cell. 2022;185(5):881-895.e20.
  • Fernández-de-Las-Peñas C, Guijarro C, Torres-Macho J, et al. Diabetes and the Risk of Long-term Post-COVID Symptoms. Diabetes. 2021;70(12):2917-292. https://doi.org/10.2337/db21-0329
  • Pavli A, Theodoridou M, Maltezou HC. Post-COVID Syndrome: Incidence, Clinical Spectrum, and Challenges for Primary Healthcare Professionals. Arch Med Res. 2021 Aug;52(6):575-581. https://doi.org/10.1016/j.arcmed.2021.03.010
  • Tleyjeh IM, Saddik B, AlSwaidan N, et al. Prevalence and predictors of Post-Acute COVID-19 Syndrome (PACS) after hospital discharge: A cohort study with 4 months median follow-up. PLoS One. 2021;16(12):e0260568. https://doi.org/10.1371/journal.pone.0260568
  • Anjana NKN, Annie TT, Siba S, Meenu MS, Chintha S, Anish TSN. Manifestations and risk factors of post COVID syndrome among COVID-19 patients presented with minimal symptoms - A study from Kerala, India. J Family Med Prim Care. 2021;10(11):4023-4029. https://doi.org/10.4103/jfmpc.jfmpc_851_21
  • Subramanian A, Nirantharakumar K, Hughes S, et al. Symptoms and risk factors for long COVID in non-hospitalized adults. Nat Med. 2022;28(8):1706-14. https://doi.org/10.1038/s41591-022-01909-w
  • Cirulli ET, Schiabor Barrett KM, Riffle S, et al. Long-term COVID-19 symptoms in a large unselected population. medRxiv. 2020.10.07.20208702. https://doi.org/10.1101/2020.10.07.20208702
  • Mahmoud N, Radwan N, Alkattan A, et al. Post-COVID-19 syndrome: nature of symptoms and associated factors. Z Gesundh Wiss. 2023 Jan 3:1-6.
  • Aminian A, Bena J, Pantalone KM, et al. Association of obesity with postacute sequelae of COVID-19. Diabetes Obes Metab. 2021;23(9):2183-8. https://doi.org/10.1111/dom.14454
  • Boscolo-Rizzo P, Guida F, Polesel J, et al. Sequelae in adults at 12 months after mild-to-moderate coronavirus disease 2019 (COVID-19). Int Forum Allergy Rhinol. 2021;11(12):1685-8. https://doi.org/10.1002/alr.22832
  • Maestre-Muniz MM, Arias A, Mata-Vazquez E, et al. Long-Term Outcomes of Patients with Coronavirus Disease 2019 at One Year after Hospital Discharge. J Clin Med. 2021;10(13):2945. https://doi.org/10.3390/jcm10132945
  • Zhang X, Wang F, Shen Y, et al. Symptoms and Health Outcomes Among Survivors of COVID-19 Infection 1 Year After Discharge From Hospitals in Wuhan, China. JAMA Netw Open. 2021;4(9):e2127403. https://doi.org/10.1001/jamanetworkopen.2021.27403a
Year 2024, , 41 - 47, 02.09.2024
https://doi.org/10.17944/interdiscip.1412206

Abstract

References

  • COVID-19. JAMA. 2020;324(6):603-605. https://doi.org/10.1001/jama.2020.12603
  • Moldofsky H, Patcai J. Chronic widespread musculoskeletal pain, fatigue, depression and disordered sleep in chronic post-SARS syndrome; a case-controlled study. BMC Neurol. 2011;11:37. https://doi.org/10.1186/1471-2377-11-37
  • Disease Manifestations and Complications: CDC & IDSA 2022: Post COVID/Long COVID [cited 2022 04.06.2020]. https://www.idsociety.org/covid-19-real-time-learning-network/disease-manifestations--complications/post-covid-syndrome.
  • Halpin SJ, McIvor C, Whyatt G, et al. Postdischarge symptoms and rehabilitation needs in survivors of COVID-19 infection: A cross-sectional evaluation. J Med Virol. 2021;93(2):1013-22. https://doi.org/10.1002/jmv.26368
  • Kamal M, Abo Omirah M, Hussein A, Saeed H. Assessment and characterisation of post-COVID-19 manifestations. Int J Clin Pract. 2021;75(3):e13746. https://doi.org/10.1111/ijcp.13746
  • Han Q, Zheng B, Daines L, Sheikh A. Long-Term Sequelae of COVID-19: A Systematic Review and Meta-Analysis of One-Year Follow-Up Studies on Post-COVID Symptoms. Pathogens. 2022;11(2):269. https://doi.org/10.3390/pathogens11020269
  • Huang L, Yao Q, Gu X, et al. 1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study. Lancet. 2021;398(10302):747-58. https://doi.org/10.1016/S0140-6736(21)01755-4
  • Su Y, Yuan D, Chen DG, et al. Multiple early factors anticipate post-acute COVID-19 sequelae. Cell. 2022;185(5):881-895.e20.
  • Fernández-de-Las-Peñas C, Guijarro C, Torres-Macho J, et al. Diabetes and the Risk of Long-term Post-COVID Symptoms. Diabetes. 2021;70(12):2917-292. https://doi.org/10.2337/db21-0329
  • Pavli A, Theodoridou M, Maltezou HC. Post-COVID Syndrome: Incidence, Clinical Spectrum, and Challenges for Primary Healthcare Professionals. Arch Med Res. 2021 Aug;52(6):575-581. https://doi.org/10.1016/j.arcmed.2021.03.010
  • Tleyjeh IM, Saddik B, AlSwaidan N, et al. Prevalence and predictors of Post-Acute COVID-19 Syndrome (PACS) after hospital discharge: A cohort study with 4 months median follow-up. PLoS One. 2021;16(12):e0260568. https://doi.org/10.1371/journal.pone.0260568
  • Anjana NKN, Annie TT, Siba S, Meenu MS, Chintha S, Anish TSN. Manifestations and risk factors of post COVID syndrome among COVID-19 patients presented with minimal symptoms - A study from Kerala, India. J Family Med Prim Care. 2021;10(11):4023-4029. https://doi.org/10.4103/jfmpc.jfmpc_851_21
  • Subramanian A, Nirantharakumar K, Hughes S, et al. Symptoms and risk factors for long COVID in non-hospitalized adults. Nat Med. 2022;28(8):1706-14. https://doi.org/10.1038/s41591-022-01909-w
  • Cirulli ET, Schiabor Barrett KM, Riffle S, et al. Long-term COVID-19 symptoms in a large unselected population. medRxiv. 2020.10.07.20208702. https://doi.org/10.1101/2020.10.07.20208702
  • Mahmoud N, Radwan N, Alkattan A, et al. Post-COVID-19 syndrome: nature of symptoms and associated factors. Z Gesundh Wiss. 2023 Jan 3:1-6.
  • Aminian A, Bena J, Pantalone KM, et al. Association of obesity with postacute sequelae of COVID-19. Diabetes Obes Metab. 2021;23(9):2183-8. https://doi.org/10.1111/dom.14454
  • Boscolo-Rizzo P, Guida F, Polesel J, et al. Sequelae in adults at 12 months after mild-to-moderate coronavirus disease 2019 (COVID-19). Int Forum Allergy Rhinol. 2021;11(12):1685-8. https://doi.org/10.1002/alr.22832
  • Maestre-Muniz MM, Arias A, Mata-Vazquez E, et al. Long-Term Outcomes of Patients with Coronavirus Disease 2019 at One Year after Hospital Discharge. J Clin Med. 2021;10(13):2945. https://doi.org/10.3390/jcm10132945
  • Zhang X, Wang F, Shen Y, et al. Symptoms and Health Outcomes Among Survivors of COVID-19 Infection 1 Year After Discharge From Hospitals in Wuhan, China. JAMA Netw Open. 2021;4(9):e2127403. https://doi.org/10.1001/jamanetworkopen.2021.27403a
There are 19 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Research Articles
Authors

Hasan Açık 0000-0002-7247-8164

Gülen Açık 0000-0003-4723-6523

Publication Date September 2, 2024
Submission Date December 30, 2023
Acceptance Date June 3, 2024
Published in Issue Year 2024

Cite

Vancouver Açık H, Açık G. Factors Associated with Post-COVID Syndrome Three Months After COVID-19. Interdiscip Med J. 2024;15(52):41-7.