In vitro Antidiabetic Activities of Two Sorbus Species

Year 2017, , 57 - 60, 27.12.2017

Gozde Hasbal Tugba Yilmaz Ozden , Ayse Can

https://doi.org/10.5152/EurJBiol.2017.1710

Abstract

Fruits
of several Sorbus species (Rosaceace) are used both in traditional medicine as
antidiabetic, antiinflammatory, diuretic, vasoprotective and in foods. In this
study, in vitro antidiabetic activities of water extracts of Sorbus aucuparia
L. (rowan tree) and Sorbus torminalis L. Crantz (wild sevice tree) fruits were
investigated by measuring inhibitory potentials on α-glucosidase and pancreatic
α-amylase activities, the most important digestive enzymes. Also, the total
phenolic and flavonoid contents of the fruits were determined to evaluate the
association between phenolic content and antidiabetic activity. S. torminalis and
S. aucuparia extracts exhibited strong α-glucosidase inhibitory activity, more
effective than that of standard drug acarbose. However, S. torminalis has shown
moderate inhibitory effect against α-amylase while S. aucuparia exhibited weak
inhibition. The total phenolic and flavonoid contents of the fruits were
correlated with andiabetic activities. It has been suggested that antidiabetic
effects of the fruits may be due to phenolic compounds present therein.
Therefore, S. aucuparia and S. torminalis fruits might be potential sources of
antidiabetic compounds.

Keywords

: Sorbus aucuparia, Sorbus torminalis, antidiabetic activity, α-amylase, α-glucosidase

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