SAFRA KESESİNİN PRİMER MÜSİNÖZ KİSTİK NEOPLAZMI: NADİR BİR VAKA

Year 2022, Volume: 85 Issue: 1, 133 - 135, 25.01.2022

Halil İbrahim Taşcı , Hilal Erinanc , Emin Turk , Erdal Karagülle

https://doi.org/10.26650/IUITFD.940494

Abstract

Safra kesesinden kaynaklanan kistik lezyonlar çok nadirdir. Hepato- bilier sisteminin müsinöz kistik neoplazileri esas olarak karaciğerde meydana gelir ve bunu ekstrahepatik biliyer sistem izler. Primer olarak safra kesesi tutulumu olan sadece birkaç vaka raporu bildirilmiştir. Karın sağ üst tarafta yemek sonrası artan karın ağrısı ve dispepsi şikayetleri olan 63 yaşında kadın hasta hastanemize başvurdu. Laparoskopik kolesistektomi yapıldı. Makroskopik olarak kist fundusun serozasında lokalize edildi ve immünohistokimyasal inceleme neticesine göre safra kesesinin primer müsinöz kistik neoplazisi olarak değerlendirildi. Her ne kadar çok nadir görülse de, safra kesesinin kistik lezyonlarında musinöz kistik neoplaziler mutlaka akılda tutulmalıdır. Böyle hastalarda malign transformasyon ve özellikle daha büyük kistlerde safra kanalı tıkanıklığı gibi riskler nedeniyle kolesistektomi yapılması zorunludur.

Keywords

Kolesistektomi, safra kesesi, müsinöz kistik neoplazi

A RARE CASE: PRIMARY MUCINOUS CYSTIC NEOPLASM OF THE GALLBLADDER

Abstract

Cystic lesions originating from the gallbladder are very rare. Mucinous cystic neoplasms of the liver and biliary system principally occur in the liver, followed by the extrahepatic biliary system. Only a few case reports were reported primarily in the gallbladder. A 63-year-old woman was admitted to our hospital with complaints of pain in the right upper abdomen, increasing after meals, and abdominal discomfort. A laparoscopic cholecystectomy was performed. Macroscopically, the cyst was localized in the serosa of the fundus. Based on immunohistochemical examination, the cyst was diagnosed as primary mucinous cystic neoplasia of the gallbladder. Although it is very rare, mucinous cystic neoplasia should be kept in mind when dealing with cystic lesions of the gallbladder. Due to serious associated problems such as the risk of malignant transformation or bile duct obstruction, particularly in larger cysts, a cholecystectomy is mandatory.

Keywords

Cholecystectomy, gallbladder, mucinous cystic neoplasia

References

• 1. Rivero-Soto RJ, Zadeh ZH, Coleman J, Ahuja V. A mucinous cystic neoplasm originating from the gallbladder: A case report and literature review. Perm J 2019;23:18-77. [CrossRef]
• 2. Safari MT, Shahrokh S, Miri MB, Foroughi F, Sadeghi A. Biliary mucinous cystic neoplasm: a case report and review of the literature. Gastroenterol Hepatol Bed Bench 2016;9(Suppl1):S88-92.
• 3. Vogt DP, Henderson JM, Chmielewski E. Cystadenoma and cystadenocarcinoma of the liver: a single center experience. J Am Coll Surg 2005;200(5):727-33. [CrossRef]
• 4. Gokalp G, Dusak A, Topal NB, Aker S. Cystadenoma originating from the gallbladder. J Ultrasound Med 2010;29(4):663-6. [CrossRef]
• 5. Sugawara S, Hirai I, Watanabe T, Tezuka K, Kimura W. A case of mucinous cystic neoplasm of the gallbladder. Clin J Gastroenterol 2018;11(5):428-32. [CrossRef]
• 6. Moussa M, Douard R, Marzouk I, Kort I, Mekni A. Biliary cystadenoma and cystadenocarcinoma of the gallbladder: a clinical review. Am Surg 2017;83(6):e186-8. [CrossRef]
• 7. McCague A, Rosen M, O’Malley K. Laparoscopic cholecystectomy of a polypoid gallbladder cystadenoma obstructing the common bile duct. Surg Laparosc Endosc Percutan Tech 2008;18(2):209-12. [CrossRef]
• 8. Sharma S, Sasaki K, Allende D, Bennett A, Aucejo FN. Biliary mucinous cystic neoplasm: a classic presentation of a rare neoplasm. J GastrointestSurg 2019;23(4):874-6. [CrossRef]
• 9. Spector SA, Fernandez VE, Vernon SE, Dunkin B, Livingstone AS. Gallbladder cystadenoma and common bile duct obstruction. Int J Gastrointest Cancer 2003;34(2- 3):151-5. [CrossRef]