Evaluation of biological activity of Diplotaenia cachrydifolia Boiss. that medicinal plant

Year 2019, Volume: 49 Issue: 2, 45 - 52, 01.08.2019

Serpil Ugraş , Sultan Ülger Pınar Göç Rasgele

Abstract

DOI: 10.26650/IstanbulJPharm.2019.18001

The aim of this study is to evaluate the
antimicrobial, antioxidant, and antigenotoxic activity of extracts obtained
from Diplotaenia cachrydifolia Boiss, which is traditionally used for food and
medical treatment by the local people of Hakkâri Province (Turkey). As a result
of this study, the extracts of D. cachrydifolia exhibited a broad antimicrobial
spectrum and high antimicrobial activity. It was also observed that the
extracts had a high antioxidant activity. The DPPH IC50 values of the extracts
were 2.5234 µg/mL, 6.0075 µg/mL, and 29.1974 µg/mL for ethanol, acetone, and
hexane, respectively. The highest phenol content was found to be 55.36±0.035
μg/mL for ethanol. Furthermore, the ethanol extract was found to have a
protective effect against mitomycin C-induced genotoxicity. D. cachrydifolia
has a high biological activity; therefore, it is anticipated that future
pharmacological studies will shed more light on this plant. 

Cite this article as: Uğraş S, Ülger S, Göç
Rasgele P (2019). Evaluation of biological activity of Diplotaenia
cachrydifolia Boiss. that medicinal plant. Istanbul J Pharm 49 (2): 45-52.

Keywords

Biological activity, genotoxicity, Diplotaenia cachrydifolia, DPPH, phenolic component

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