Antioxidant supplements: Positive or negative actors in orthodontic treatment

Rumeysa Bilici Geçer; Gül Özhan; Derya Dursun

doi:10.26650/IstanbulJPharm.2023.1329006

Review

Antioxidant supplements: Positive or negative actors in orthodontic treatment

Year 2023, Volume: 53 Issue: 3, 358 - 367, 28.12.2023

Rumeysa Bilici Geçer , Gül Özhan , Derya Dursun

https://doi.org/10.26650/IstanbulJPharm.2023.1329006

Abstract

Antioxidant supplements are popular and commonly considered healthy benefits such as reducing the risk of disease. It should be noted that their advantages/disadvantages are still unclear. Some research on antioxidants shows that they may reduce the risk of cancer, heart disease, neurodegenerative diseases, and some chronic diseases, and have various health benefits such as a positive effect on bone metabolism by supporting bone regeneration. Some of them show that the benefits of antioxidant supplements are not clear and indicate to increase the risk. The effects of antioxidants on orthodontic treatment are now being studied extensively due to their widespread use. Antioxidants that regulate bone modulation can be used to reduce orthodontic treatment time, accelerate tooth movement, or in some cases prevent unwanted tooth movement, but their unconscious use can adversely affect the orthodontic treatment. Understanding the mechanisms of action of antioxidants and their effects on orthodontic treatment can increase the success of treatment and prevent adverse situations that may occur due to the use of antioxidants. Many inflammatory mediators play a role in the response to mechanical forces in orthodontic treatment. Increased expression of pro-inflammatory cytokines is associated with oxidative stress. Antioxidants can affect remodeling processes in which osteoblast and osteoclast cells play a role, such as relapse, anchorage, and bone formation after maxillary expansion in orthodontic treatment. The use of antioxidants in orthodontic treatment may increase tooth movement and shorten retention time by increasing osteoblastic activity after maxillary expansion, or on the contrary, slow tooth movement and prolong treatment time by reducing oxidative stress and inflammation. Accordingly, factors such as the desired effect in orthodontic treatment and the phase of treatment should be considered when using antioxidants. We aimed to provide information and suggestions for evaluating the effectiveness of antioxidant use in orthodontic treatment with basic information about antioxidants.

Keywords

Antioxidant supplements, orthodontic treatment, oxidative stress

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Year 2023, Volume: 53 Issue: 3, 358 - 367, 28.12.2023

Rumeysa Bilici Geçer , Gül Özhan , Derya Dursun

https://doi.org/10.26650/IstanbulJPharm.2023.1329006

Abstract

References

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There are 90 citations in total.

Details

Primary Language	English
Subjects	Pharmaceutical Toxicology
Journal Section	Review
Authors	Rumeysa Bilici Geçer 0009-0001-0839-5831 Gül Özhan 0000-0002-6926-5723 Derya Dursun 0000-0002-6592-9502
Publication Date	December 28, 2023
Submission Date	July 18, 2023
Published in Issue	Year 2023 Volume: 53 Issue: 3

Cite

APA	Bilici Geçer, R., Özhan, G., & Dursun, D. (2023). Antioxidant supplements: Positive or negative actors in orthodontic treatment. İstanbul Journal of Pharmacy, 53(3), 358-367. https://doi.org/10.26650/IstanbulJPharm.2023.1329006
AMA	Bilici Geçer R, Özhan G, Dursun D. Antioxidant supplements: Positive or negative actors in orthodontic treatment. iujp. December 2023;53(3):358-367. doi:10.26650/IstanbulJPharm.2023.1329006
Chicago	Bilici Geçer, Rumeysa, Gül Özhan, and Derya Dursun. “Antioxidant Supplements: Positive or Negative Actors in Orthodontic Treatment”. İstanbul Journal of Pharmacy 53, no. 3 (December 2023): 358-67. https://doi.org/10.26650/IstanbulJPharm.2023.1329006.
EndNote	Bilici Geçer R, Özhan G, Dursun D (December 1, 2023) Antioxidant supplements: Positive or negative actors in orthodontic treatment. İstanbul Journal of Pharmacy 53 3 358–367.
IEEE	R. Bilici Geçer, G. Özhan, and D. Dursun, “Antioxidant supplements: Positive or negative actors in orthodontic treatment”, iujp, vol. 53, no. 3, pp. 358–367, 2023, doi: 10.26650/IstanbulJPharm.2023.1329006.
ISNAD	Bilici Geçer, Rumeysa et al. “Antioxidant Supplements: Positive or Negative Actors in Orthodontic Treatment”. İstanbul Journal of Pharmacy 53/3 (December 2023), 358-367. https://doi.org/10.26650/IstanbulJPharm.2023.1329006.
JAMA	Bilici Geçer R, Özhan G, Dursun D. Antioxidant supplements: Positive or negative actors in orthodontic treatment. iujp. 2023;53:358–367.
MLA	Bilici Geçer, Rumeysa et al. “Antioxidant Supplements: Positive or Negative Actors in Orthodontic Treatment”. İstanbul Journal of Pharmacy, vol. 53, no. 3, 2023, pp. 358-67, doi:10.26650/IstanbulJPharm.2023.1329006.
Vancouver	Bilici Geçer R, Özhan G, Dursun D. Antioxidant supplements: Positive or negative actors in orthodontic treatment. iujp. 2023;53(3):358-67.

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