Abstract
GYNECOLOGIC PATHOLOGY COMPLEX IN A BITCH A 10 years old, intact, nulliparus, 7 kg in body weight, mixed bred bitch was presented to our clinic with vaginal mass, various sized tumoral masses on mammary tissue and anorexia. Pyometra and cystic structures on both ovaries were observed by ultrasonographic examination. As a surgical approach, ovariohysterectomy, bilateral mastectomy and extirpation of vaginal mass were applied in the same general anesthesia. Pathologic examination revealed several follicular cysts on both ovaries. In histological sections of the uterus, lumen intense neutrophil leukocytes in and pus which was formed by degenerated epithelia confirmed the presence of pyometra. It was identified histopathologically that the vaginal mass was a leiomyoma and the masses on mammary tissues were Adenocarcinoma grade II.
References
- Aralığı WBC (x 10 3 µl -1 ) 70,8 6-17 RBC (x 10 6 µl -1 ) 3,91 5,5-8,5 HGB (g dl -1 ) 8,1 12-18 HCT (%) 24 37-55 PLT (x 10 3 µl -1 ) 34 200-500 AST (iu l -1 ) 22 5-55 ALT (iu l -1 ) 21 5-60 Üre (mg dl -1 ) 34 7-27 Kreatinin (mg dl -1 ) 0,9 0,4-1,8 Glikoz (mg dl -1 ) 84 60-125 Bergh, J., Noberg, T., Sjogren, S., Lindgren, A., Holmberg, L., Coplete, J., 1995. Squencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemictherapy and radiotherapy. Nature Medicine 1, 1029-1034.
- Blendinger, K., Bostedt, H., Hoffmann, B., 1997. Hormonal state and effects of the use of an antiprogestin in bitches with pyometra. Journal of Reproduction and Fertility 51 (suppl), 3173
- Cotchine, E., Marchant, J., 1977. Animal tracts of the female reproductive tract: spontaneous and experimental. New York, Springer-Verlag, pp. 16Dinç, D.A., 1999. Evcil hayvanlarda Doğum ve İnfertilite. In: Alaçam, E. (Ed), Karnivorlarda İnfertilite. Medisan Yayınları, Ankara, pp. 3243
- Fayrer-Hosken, R.A., Durham, D.H., Allen, S., Miller-Leiblü, D.M., Caudle, A.B., 1982. Follicular cystic ovaries and cystic endometrial hyperplasia in a bitch. Journal of the American Veterinary Medical Association 201 (1), 107
- Johnston, S.D., Kustritz, M.V.R., Olson, P.N.S., 200 Disorders of the canine ovary. In: Johnston S.D. (Ed), Canine and Feline Theriogeneology. Philadelphia, WB Saunders Company, Pennsylvania, pp. 195-198. Kang, T.B., Holmberg, D.L., 1983. Vaginal leiomyoma in a dog. Canadian Veterinary Journal 24, 258-260.
- Kırşan, İ., Uçmak, M., Apaydın, S., 2005. Clinical evaluation of the complications found in bitches after total bilateral mastectomy operations. Medycyna Weterynaryjna 61 (5), 507-509.
- Nelson, R.W., Feldman, E.C., 1986. Pyometra in the bitch. In: Morrow, D.A. (Ed), Current Therapy in Theriogenology 2. Philadelphia, WB Saunder Company, pp. 484-489.
- Queirogaa, F.L., Perez-Alenzab, M.D., Silvanc, G., Penab, L., Lopesd, C., Illerac, J.C., 2005. Role of steroid hormones and prolactin in canine mammary cancer. The Journal of Steroid Biochemistry and Molecular Biology 94, 1811
- Schneider, R., Dorn, C.R., Taylor, D.O.N., 1969. Factors influencing canine mammary cancer development and postsurgical survival. The Journal of National Cancer Institute 43 (6), 1249–1261.
- Smith, K.W., 1974. Female genital system. In: Archibald, J., Barbara, S. (Ed), Canine surgery. American Veterinary Publications Inc., California, pp. 751-782.
- Sorenmo, K., 2003. Canine mammary gland tumors. Veterinary Clinics of North America Small Animal Practice 33, 573-596.
- Susaneck, S.J., 1981. Tumors of the female reproductive tract. In: Collins, F. (Ed), Oncology Notes. Comparative Oncology Unit, Colorado State University.
- Theilen, G.H., Madewell, B.R., 1979. Tumors of the urogenital tract. In: Madewell, B.R., Theilen, G.H. (Ed), Veterinary Cancer Medicine. Lea&Febiger, Philedelphia, pp. 245-2
Abstract
ÖZET
10 yaşında, kısırlaştırılmamış, hiç doğum yapmamış, 7 kg ağırlığında, melez dişi bir köpek, vaginal kitle, meme loblarında değişen büyüklükte tümöral oluşumlar ve iştahsızlık nedenleriyle kliniğimize getirildi. Yapılan ultrasonografik muayene sonucunda pyometra ve her iki ovaryumda kistik oluşumlar gözlendi. Tek bir genel anestezi altında cerrahi yaklaşım olarak ovariohisterektomi, bilateral mastektomi ve vaginal kitlenin ekstirpasyonu uygulandı. Patolojik inceleme sonucunda her iki ovaryumda çok sayıda folliküler kistler belirlendi. Yapılan histolojik kesitlerde uterus lumeninde yoğun biçimde nötrofil lökosit ve dejenere epitellerin görülmesi pyometra varlığını teyit etti. Histopatoloji sonucuna göre vaginal kitlenin leiomiyom ve meme dokularındaki kitlelerin II. derece Adenokarsinom olduğu saptandı.
Anahtar Kelimeler: Dişi köpek, vaginal leiomiyom, pyometra, meme tümörü, kistik ovaryum
ABSTRACT
GYNECOLOGIC PATHOLOGY COMPLEX IN A BITCH
A 10 years old, intact, nulliparus, 7 kg in body weight, mixed bred bitch was presented to our clinic with vaginal mass, various sized tumoral masses on mammary tissue and anorexia. Pyometra and cystic structures on both ovaries were observed by ultrasonographic examination. As a surgical approach, ovariohysterectomy, bilateral mastectomy and extirpation of vaginal mass were applied in the same general anesthesia. Pathologic examination revealed several follicular cysts on both ovaries. In histological sections of the uterus, lumen intense neutrophil leukocytes in and pus which was formed by degenerated epithelia confirmed the presence of pyometra. It was identified histopathologically that the vaginal mass was a leiomyoma and the masses on mammary tissues were Adenocarcinoma grade II.
Key Words: Bitch, vaginal leiomyoma, pyometra, mammary tumor, cystic ovary
References
- Aralığı WBC (x 10 3 µl -1 ) 70,8 6-17 RBC (x 10 6 µl -1 ) 3,91 5,5-8,5 HGB (g dl -1 ) 8,1 12-18 HCT (%) 24 37-55 PLT (x 10 3 µl -1 ) 34 200-500 AST (iu l -1 ) 22 5-55 ALT (iu l -1 ) 21 5-60 Üre (mg dl -1 ) 34 7-27 Kreatinin (mg dl -1 ) 0,9 0,4-1,8 Glikoz (mg dl -1 ) 84 60-125 Bergh, J., Noberg, T., Sjogren, S., Lindgren, A., Holmberg, L., Coplete, J., 1995. Squencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemictherapy and radiotherapy. Nature Medicine 1, 1029-1034.
- Blendinger, K., Bostedt, H., Hoffmann, B., 1997. Hormonal state and effects of the use of an antiprogestin in bitches with pyometra. Journal of Reproduction and Fertility 51 (suppl), 3173
- Cotchine, E., Marchant, J., 1977. Animal tracts of the female reproductive tract: spontaneous and experimental. New York, Springer-Verlag, pp. 16Dinç, D.A., 1999. Evcil hayvanlarda Doğum ve İnfertilite. In: Alaçam, E. (Ed), Karnivorlarda İnfertilite. Medisan Yayınları, Ankara, pp. 3243
- Fayrer-Hosken, R.A., Durham, D.H., Allen, S., Miller-Leiblü, D.M., Caudle, A.B., 1982. Follicular cystic ovaries and cystic endometrial hyperplasia in a bitch. Journal of the American Veterinary Medical Association 201 (1), 107
- Johnston, S.D., Kustritz, M.V.R., Olson, P.N.S., 200 Disorders of the canine ovary. In: Johnston S.D. (Ed), Canine and Feline Theriogeneology. Philadelphia, WB Saunders Company, Pennsylvania, pp. 195-198. Kang, T.B., Holmberg, D.L., 1983. Vaginal leiomyoma in a dog. Canadian Veterinary Journal 24, 258-260.
- Kırşan, İ., Uçmak, M., Apaydın, S., 2005. Clinical evaluation of the complications found in bitches after total bilateral mastectomy operations. Medycyna Weterynaryjna 61 (5), 507-509.
- Nelson, R.W., Feldman, E.C., 1986. Pyometra in the bitch. In: Morrow, D.A. (Ed), Current Therapy in Theriogenology 2. Philadelphia, WB Saunder Company, pp. 484-489.
- Queirogaa, F.L., Perez-Alenzab, M.D., Silvanc, G., Penab, L., Lopesd, C., Illerac, J.C., 2005. Role of steroid hormones and prolactin in canine mammary cancer. The Journal of Steroid Biochemistry and Molecular Biology 94, 1811
- Schneider, R., Dorn, C.R., Taylor, D.O.N., 1969. Factors influencing canine mammary cancer development and postsurgical survival. The Journal of National Cancer Institute 43 (6), 1249–1261.
- Smith, K.W., 1974. Female genital system. In: Archibald, J., Barbara, S. (Ed), Canine surgery. American Veterinary Publications Inc., California, pp. 751-782.
- Sorenmo, K., 2003. Canine mammary gland tumors. Veterinary Clinics of North America Small Animal Practice 33, 573-596.
- Susaneck, S.J., 1981. Tumors of the female reproductive tract. In: Collins, F. (Ed), Oncology Notes. Comparative Oncology Unit, Colorado State University.
- Theilen, G.H., Madewell, B.R., 1979. Tumors of the urogenital tract. In: Madewell, B.R., Theilen, G.H. (Ed), Veterinary Cancer Medicine. Lea&Febiger, Philedelphia, pp. 245-2
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | March 10, 2013 |
| Published in Issue | Year 2013 Volume: 39 Issue: 2 |