KORONER ARTER CERRAHİSİ ÖNCESİNDE ASETİLSALİSİK ASİT KULLANAN HASTALARLA KULLANMAYANLARIN POSTOPERATİF DÖNEMDE MEDİYASTİNAL DRENAJ VE FARKLI DEĞİŞKENLERİNİN KARŞILAŞTIRILMASI

Year 2013, Volume: 17 Issue: 4, 188 - 197, 01.12.2013

Barçın Özcem Mehmet Bademci Muhammet Akyüz Serkan Yazman Ersin Çelik , Övünç Aslan İsmail Yürekli Serdar Bayrak Ali Gürbüz Ufuk Yetkin

Abstract

Bu çalışmanın amacı; koroner arter bypass greftleme operasyonuna kadar günde 100 mg enterik kaplı ASA tablet kullanan hastalarla, kullanmayan hastaların postoperatif dönemde mediyastinal drenaj, kan ve kan ürünleri transfüzyon miktarları ve mortalite gibi postoperatif değişkenlerinin irdelenip anlamlı fark olup olmadığının saptanmasıdır. Kliniğimizde Ocak 2011-Aralık 2011 tarihleri arasında koroner arter bypass greftleme cerrahisi uygulanan 61 koroner arter hastası retrospektif olarak incelendi.Çalışmaya dahil edilen 61 hastanın 49’u %80.3 kardiyopulmoner bypass cihazı kullanılarak, 12’si %19.7 ise atan kalpte ameliyat edilmiştir. Kardiyopulmoner bypass cihazı kullanılarak ve atan kalpte ameliyat edilen her iki farklı grupta da ASA’nın istatistiksel olarak anlamlı bir kanamaya neden olmadığı, ayrıca mediyastinal re-eksplorasyon, inotropik kullanımı, kan transfüzyonları, intraortik balon kullanımı ve mortalite gibi değişkenlerde ASA kullanmayan gruba göre yine istatistiksel olarak anlamlı bir fark bulunmadığını da saptadık. ASA’nın koroner arter bypass greftleme cerrahisi öncesinde kesilmesi gerekmemektedir. Kaldıki 2011 ACCF/AHA kılavuzunda da preoperatif ASA kullanımı klas I olarak gösterilmiş olup çalışmamızda elde olunan bulgularımız kılavuzdaki bilgilerle uyum göstermektedir

Keywords

Asetil salisilik asit, koroner arter bypass greftleme cerrahisi, mediyastinal drenaj, mortalite

COMPARISON OF PATIENTS WITH AND WITHOUT PREOPERATIVE SALICYLATE USE IN TERMS OF POSTOPERATIVE MEDIASTINAL DRAINAGE AND DIFFERENT CHANGES

Abstract

The aim of study is to compare preoperative groups with and without 100mg enteric coated ASA in aspects of mediastinal drainage, blood transfusion amounts and mortality rates. We evaluated 61 patients who were operated in our clinic between January 2011-December 2011. Among them, 49 patients 80,3% were operated on cardiopulmonary bypass and 12 patients 19.7% were operated off pump. We found no statistically significant difference in postoperative term on bleeding, revision requirement, inotropic support need, blood transfusion amounts, intraaortic balon pump need and mortality rate. We revealed that it is not obligatory to stop ASA before operation date. In 2011 ACCF/AHA guideline, preoperative ASA usage has class 1 indication and our results are compatible with that

Keywords

Asetylsalicylic acid, coronary artery bypass surgery, mediastinal drainage, mortality rate

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