REKOMBİNANT HEPATİT B AŞISI SONRASI NEONATAL FEBRİL KONVULZİYON OLGUSU
Year 2018,
Volume: 3 Issue: 3, 104 - 110, 06.12.2018
Hatice Eke Güngör
,
Mustafa Çalık
,
Hüseyin Gümüş
Akin İşcan
Abstract
Hepatit B
virüsüne (HBV) karşı aşılama HBV enfeksiyonlarını azaltmak için önemlidir. HBV
aşısı diğer aşılara kıyasla daha güvenli olmasına rağmen birçok yan etki ile
ilişkili bulunmuştur. Otoimmün
ve nörolojik bozukluklar aşıyı takiben gelişebilmektedir. Multipl skleroz
sıklıkla bildirilmesine rağmen nörit, myastenia gravis, Guillain–Barre sendromu,
febril ve afebril konvulziyonlar da görülebilmektedir. Burada HBV aşısı sonrası
3. günde febril konvulziyon geçiren 35 günlük kız olgu sunuldu. HBV aşısı
güvenli olmasına rağmen gelişebilecek komplikasyonlar açısından dikkatli olunmalıdır.
References
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- after immunisation with recombinant hepatitis B vaccine. Lancet 1991; 338:
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- Vaccine 2007; 25(31): 5938–5943.
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- 10. Nehama Linder, Meirav Raz, Lea Sirota, Brian Reichman, Dan Lubin, Jacob Kuint. Unexplained fever in neonates may be associated with hepatitis B vaccine. Arch Dis Child Fetal Neonatal Ed 1999;81:206–207
Year 2018,
Volume: 3 Issue: 3, 104 - 110, 06.12.2018
Hatice Eke Güngör
,
Mustafa Çalık
,
Hüseyin Gümüş
Akin İşcan
References
- 1. Moradpour D, VandsJR. Understanding Hepatitis B virus infection. N Eng J Med 1995; 332: 1092–1093.
- 2. Herroelen D, De Keyser J, Ebinger G. Central-nervous-system demyelination
- after immunisation with recombinant hepatitis B vaccine. Lancet 1991; 338:
- 1174-1175.
- 3. Hocine MN, Farrington CP, Touze´ E, Whitaker HJ, Fourrier A, Moreau T et al. Hepatitis B accination and first central nervous system demyelinating events: reanalysis of a case-control study using the self-controlled case series method.
- Vaccine 2007; 25(31): 5938–5943.
- 4. Farez F M, Correale J. Immunizations and risk of multiple sclerosis: systematic review and meta-analysis. J Neurol 2011; 258:1197–1206.
- 5. Shaw FE, Graham DJ, Guess HA, et al. Postmarketing surveillance for
- neurologic adverse events reported after hepatitis B vaccination. Experience of
- the first three years. Am J Epidemiol 1988; 127: 337-352.
- 6. Borchers AT, Keen CL, Shoenfeld Y, Silva Jr J, Gerswin ME. Vaccines,
- viruses and voodoo. J Investig Allergol Clin Immunol 2002; 12:155–168.
- 7. Kaygusuz S, Erdemoglu AK, Köksal I. Afebrile convulsion in an adult after recombinant hepatitis B vaccination. Scand J Infect Dis 2002; 34(4): 314-315.
- 8. Jozélio Freire de Carvalho a,b, Yehuda Shoenfeld. Status epilepticus and lymphocytic pneumonitis following hepatitis B vaccination. Eur J Intern Med 2008; 19: 383–385.
- 9. Lewis E, Shinefield HR, Woodruff BA, Black SB, Destefano F, Chen RT et al. Safety of neonatal hepatitis B vaccine administration. Pediatr Infect Dis J 2001;20(11): 1049-1054.
- 10. Nehama Linder, Meirav Raz, Lea Sirota, Brian Reichman, Dan Lubin, Jacob Kuint. Unexplained fever in neonates may be associated with hepatitis B vaccine. Arch Dis Child Fetal Neonatal Ed 1999;81:206–207