SARS-CoV-2 Infection or Drug Allergy? Two Pediatric Cases Presenting with Angioedema
Year 2022,
Volume: 22 Issue: 2, 137 - 140, 09.09.2022
Sevgi Sipahi Çimen
,
Gizem Adan
,
Tolga Bacak
,
Nazan Dalgic
Abstract
Acute urticaria and angioedema are common clinical findings in children. Although the most common etiological factor is acute infection, drug and food allergies may also present with urticaria and angioedema. Although urticaria and angioedema have frequently been seen in severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) infections during the pandemic, underlying drug and food allergies should be kept in mind in the differential diagnosis, and a detailed history should be taken from patients. This article presents two pediatric cases where the patients presented with angioedema occurring in the febrile period and had drug allergy concomitant with positive SARS-CoV-2 PCR test result.
References
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SARS-CoV-2 Enfeksiyonu mu İlaç Alerjisi mi? Anjioödem ile Gelen İki Pediatrik Olgu Sunumu
Year 2022,
Volume: 22 Issue: 2, 137 - 140, 09.09.2022
Sevgi Sipahi Çimen
,
Gizem Adan
,
Tolga Bacak
,
Nazan Dalgic
Abstract
Akut ürtiker ve anjiyoödem çocuklarda sık görülen klinik bulgulardır. En yaygın etiyolojik faktör akut enfeksiyon olmakla birlikte, ilaç ve gıda alerjileri de ürtiker/anjiyoödem ile ortaya çıkabilir. Ürtiker ve anjiyoödem, bu pandemi döneminde Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) enfeksiyonu sırasında sık görülmekle birlikte, altta yatabilecek ilaç ve besin alerjileri ayırıcı tanıda akılda tutulmalı ve hastalardan ayrıntılı öykü alınmalıdır. Bu yazımızda ateşli dönemde ortaya çıkan anjiyo-ödem nedeniyle başvuran ve SARS-CoV-2 PCR testi pozitif olup ilaç alerjisi tanısı alan iki pediatrik vaka sunulmuştur.
Supporting Institution
yoktur
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- 5. Morey-Olivé M, Espiau M, Mercadal-Hally M, Lera-Carballo E, García-Patos V. Manifestaciones cutáneas en contexto del brote actual de enfermedad por coronavirus
2019 (Cutaneous manifestations in the current pandemic of coronavirus infection disease (COVID 2019)). An Pediatr (Engl Ed) 2020;92(6):374-5. google scholar
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Severity. J Clin Med 2020;9(10):3261. google scholar
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Epub 2020 Oct 9. google scholar
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Care Workers. Curr Allergy Asthma Rep 2020;20(12):75. google scholar
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google scholar
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scholar
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Ecancermedicalscience. 2020;14:1023. google scholar
- 15. Sakaida T, Tanimoto I, Matsubara A, Nakamura M, Morita A. Unique skin manifestations of COVID-19: Is drug eruption specific to COVID-19? J Dermatol Sci
2020;99(1):62-4. google scholar
- 16. Roberts LJ, Morrow JD. Analgesic-antipyretic and antiinflammatory agents and drugs employed in the treatment of gout. In: Hardman JG, Limbird LL, Goodman
Gilman A, editors. The pharmacological basis of therapeutics. 10th edition. New York: McGraw-Hill; 2001. p. 687-731. google scholar
- 17. Dona I, Blanca-Lopez N, Torres MJ, Garcia-Campos J, Garcia-Nunez I, Gomez F et al. Drug hypersensitivity reactions: response patterns, drug involved, and temporal
variations in a large series of patients. J Investig Allergol Clin Immunol 2012;22:363-71. google scholar
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2004;15:376-80. google scholar
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hypersensitivity to nonsteroidal antiinflammatory drugs. Allergy 2013;68(10):1219-32. google scholar