Investigation Of The Relationship Between Prognostic Nutrition Index And Mortality In Patients With Femur Fracture

Year 2023, Volume: 13 Issue: 1, 60 - 65, 31.01.2023

Öztürk Taşkın , Ufuk Demir , Ayşe Yılmaz , Selahattin Özcan , Zahide Doğanay

https://doi.org/10.16899/jcm.1210766

Abstract

Aim: The incidence of adverse postoperative outcomes in surgeries for femur fractures is high and is associated with malnutrition. In this study, it was aimed to determine the independent factors for 6-month survival in patients with femur fracture and to evaluate the predictive value of the prognostic nutrition index (PNI).

Material and Method: One hundred and sixteen patients operated on only for femoral fracture were divided into survival and non-survival groups according to mortality.Demographic characteristics of the patients, operation data, fracture sites, need for intensive care unit and length of stay, postoperative hospital stay, and preoperative laboratory values, prognostic nutrition indices and mortality were evaluated.
Results: Twenty-six (22.4%) of 116 patients who were operated for femoral fracture resulted in 6-month mortality. CRP, albumin, prealbumin, crp/albumin ratio and PNI values at admission were independent risk factors for postoperative mortality (p=0.014, p<0.001, p=0.041, p=0.003, p<0.001). The optimal cut-off value for PNI was determined as 29.0. In the group with PNI>29.0, survival rates were found to be higher at the end of the 1st, 3rd and 6th months (94.2%, 89.5%, 89.5%).
Conclusion: Nutritional indices should be evaluated when patients with femoral fractures are admitted to the hospital. A low prognostic nutritional index may a predict mortality in patients with femoral fractures.

Keywords

prognostic nutrition index, femur fracture, mortality

Femur Kırığı Olan Hastalarda Prognostik Nutrisyon İndeksi İle Mortalite Arasındaki İlişkinin Araştırılması

Abstract

Amaç: Femur kırıkları için yapılan ameliyatlarda postoperatif olumsuz sonuçların insidansı yüksektir ve yetersiz beslenme ile ilişkilidir. Bu çalışmada femur kırığı olan hastalarda 6 aylık sağkalım için bağımsız faktörlerin belirlenmesi ve prognostik beslenme indeksinin (PNI) prediktif değerinin değerlendirilmesi amaçlandı.

Gereç ve Yöntem: Sadece femur kırığı nedeniyle opere edilen 116 hasta mortaliteye göre hayatta kalan ve hayatta kalmayan gruplara ayrıldı. Hastaların demografik özellikleri, operasyon verileri, kırık bölgeleri, yoğun bakım ihtiyacı ve kalış süresi, postoperatif hastanede kalış süresi, preoperatif laboratuvar değerleri, prognostik beslenme indeksleri ve mortalite değerlendirildi.

Bulgular: Femur kırığı nedeniyle opere edilen 116 hastanın 26'sı (%22.4) 6 aylık mortalite ile sonuçlandı. CRP, albumin, prealbumin, crp/albumin oranı ve PNI değerleri postoperatif mortalite için bağımsız risk faktörleriydi (p=0.014, p<0.001, p=0.041, p=0.003, p<0.001). PNI için optimal cut-off değeri 29,0 olarak belirlendi. PNI>29.0 olan grupta 1., 3. ve 6. ay sonunda sağkalım oranları daha yüksek bulundu (%94.2, %89.5, %89.5).

Sonuç: Femur kırığı olan hastalar hastaneye kabul edildiğinde beslenme indeksleri değerlendirilmelidir. Düşük bir prognostik beslenme indeksi, femur kırığı olan hastalarda mortaliteyi öngörebilir.

Keywords

prognostik nutrisyon indeksi, femur fraktürü, mortalite

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