QT and P-Wave Dispersion of Patients with Antisocial Personality Disorder

Year 2023, Volume: 13 Issue: 2, 263 - 269, 22.03.2023

Şuheda Kaya , Gülay Taşcı , Nülüfer Kılıç , Mücahid Yılmaz Filiz Özsoy , Murad Atmaca

https://doi.org/10.16899/jcm.1224403

Abstract

Background: The purpose was to examine the electrocardiographic arrhythmia risk determinants of the QT and P-wave dispersions of the patients who have Antisocial Personality Disorder (ASPD) by comparing them with the healthy control group.
Method: A total of 52 patients who were diagnosed with ASPD according to DSM-5 Criteria and a healthy control group that consisted of 54 people were included in the study. Twelve lead Electrocardiograms (ECGs) were obtained from all participants in the supine position and at rest, and P-wave dispersion and QT dispersion were also calculated. The participants were administered the Beck Anxiety Inventory (BAI), Beck Depression Inventory (BDI), Buss-Durke Aggression Scale (BDAS), Barratt Impulsivity Scale (BIS-11), and sociodemographic clinical data form. The SPSS version 22 package program was used for statistical analyses.
Results: The mean age of the ASPD group and control group were no statistically significant differences between them (p=0.092). QT max (p=0.016), QTd (p<0.001), P max (p<0.001), and Pd (p<0.001) values of the ASPD group were higher than the values of the control group at significant levels; and QT min (p<0.001) and P min (p<0.001) values were found to be significantly lower. The BAI, BDI, BDAS scores and the motor impulsiveness score of the BIS-11 subscales of the ASPD group were significantly higher than those of the control group (p<0.001).
Discussion: The findings of study showed that ASPD patients were at risk for electrical problems of the heart, especially cardiac arrhythmia, and this must be considered in the general psychiatric follow-up of these patients.

Keywords

antisocial personality disorder, QT dispersion, P dispersion

Antisosyal Kişilik Bozukluğu Olan Hastalarda QT ve P Dalgası Dispersiyonu

Abstract

Amaç: Antisosyal kişilik bozukluğu (ASKB) olan hastalarda elektrokardiyografik aritmi risk belirleyicileri olan QT ve P dalgası dispersiyonlarının sağlıklı kontrol grubuyla karşılaştırılarak incelenmesi amaçlanmıştır.
Yöntem: Çalışmamıza DSM-5 kriterlerine göre ASKB tanısı alan 52 hasta ve 54 kişiden oluşan sağlıklı kontrol grubu dahil edildi. Tüm katılımcıların boy, kiloları, tansiyonları ölçüldü ve vücud kitle indeksleri(VKİ) hesaplandı. Vücut kitle indeksi > 24,9 kg/m2 olan katılımcılar çalışma dışı bırakıldı. Tüm katılımcılardan on iki derivasyon elektrokardiyogramı (EKG) yatar pozisyonda ve istirahatte alındı. P dalga dispersiyonu ve QT dispersiyonu hesaplandı. Ayrıca katılımcılara Beck Anksiyete Ölçeği (BAÖ), Beck Depresyon Ölçeği (BDÖ), Buss-Durke Saldırganlık Ölçeği (BDSÖ), Barratt Dürtüsellik Ölçeği (BrDÖ) ve sosyodemografik klinik veri formu uygulandı. İstatiksel analizler için SPSS versiyon 22 paket programı kullanıldı.
Sonuçlar: ASKB grubunda bulunanların yaş ortalaması 29,6±6,5, kontrol grubunun yaş ortalaması ise 31,8±7,1 olarak bulunmuş olup aralarında istatistiksel olarak anlamlı farklılık görülmemiştir (p=0,092). ASKB grubunun QT max (p=0,016), QT disp (p<0,001), P max (p<0,001), P disp (p<0,001) değeri kontrol grubunun değerlerinden anlamlı şekilde yüksek; QT min (p<0,001) ve P min (p<0,001) değeri ise anlamlı şekilde düşük bulunmuştur. ASKB grubunun BAÖ ve BDÖ puanı kontrol grubunun puanından anlamlı şekilde yüksek bulunmuştur (p<0,001). BDSÖ tüm alt ölçek puanları kontrol grubuna kıyasla daha yüksekti (p<0,001), BrDÖ alt ölçeklerinden ise motor dürtüsellik puanı ASKB grubunda daha yüksekti (p<0,001).
Tartışma: Çalışma bulgularımız ASKB hastalarının kardiyak aritmi başta olmak üzere kalbin elektriksel temelli sorunları açısından risk taşıdıkları ve bu durumun bu hastaların genel psikiyatrik takibinde göz önünde bulundurulması gerektiğini göstermektedir.

Keywords

antisosyal kişilik bozukluğu, QT dispersiyonu, P dispersiyonu

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