A Case Report of Metformin Related Lactic Acidosis

Year 2023, , 44 - 45, 07.07.2023

İlker Akbaş , Caner Akufuk , Muhammet Mustafa Yılmaz , Atilla Eren Kurt , Fatih Coşkun

https://doi.org/10.33706/jemcr.1294738

Cited By: 1

Abstract

Metformin is an oral antidiabetic drug of the biguanide classused in type 2 diabetic patients with normal renal function. The mortality rate is high in cases of lactic acidos is developing in metformin intoxication. In the emergency department, metformin intoxication should be considered in the differential diagnosis of patients whouse metformin and have high anion gap metabolic acidosis (lactic acidosis). The most important and effective treatment with early diagnosis is correction of metabolic acidosis with hemodialysis or hemofiltration methods, bicarbonate treatment, adjustment of blood glucose level. Cardiovascular system support therapy significantly reduces morbidity/mortality. In this case report, we present the early diagnosis and successful treatment of a patient with lactic acidosis due to metformin intoxication.

Keywords

Metformin, Poisoning, Lactic acidosis

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