Abstract
Introduction: Here we report a case who presented with fever, dry cough, sore throat and myalgia, mimicking COVID-19 and diagnosed as Pulmonary Tuberculosis.
Case Report: A 31-year-old female patient was presented to the COVID-19 outpatient clinic with 7-day history of fever,dry cough,night sweats,chills,sore throat,and myalgia. Laboratory results revealed lymphopenia, C-reactive protein, erythrocyte sedimentation rate and D-dimer elevation compitable with COVID-19. She was hospitalized with diagnosis of “probable COVID-19”. SARS-CoV-2 multiplex PCR were resulted negative. Chest CT revealed cavitary lesion located in the upper lobe of the right lung with uncertain borders, consolidation in the right upper lobe primarily in favor of TB infection. She had three samples of sputum acid-fast bacillus smear that came back positive. TB PCR also resulted positive.
Conclusion: Although the most common presentation of COVID-19 seems to be pneumonia, there is no unique clinical feature that reliably differentiates COVID-19 from other upper / lower airway viral or bacterial infections.
Keywords
References
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Abstract
Giriş: Bu olgu sunumunda COVID-19'u taklit ederek ateş, kuru öksürük, boğaz ağrısı ve myalji ile başvuran ve Akciğer Tüberkülozu tanısı alan bir hasta sunulmuştur.
Olgu Sunumu: 31 yaşında kadın hasta 7 gündür olan ateş, kuru öksürük, gece terlemesi, titreme, boğaz ağrısı ve kas ağrısı ile COVID-19 polikliniğine başvurdu. Laboratuvar sonuçlarında COVID-19 ile uyumlu şekilde lenfopeni, C-reaktif protein, sedimantasyon hızı ve D-dimer yüksekliği saptandı. Hasta “Olası COVID-19” tanısı ile hastaneye yatırıldı. SARS-CoV-2 PCR testi negatif sonuçlandı. Toraks BT'sinde, sağ akciğerin üst lobunda belirsiz sınırları olan kaviter lezyon, sağ üst lobda konsolidasyon saptanmış olup öncelikle Tüberküloz enfeksiyonu lehine değerlendirildi. Balgam yaymasında ARB pozitif saptandı. Balgam TB PCR pozitif sonuçlandı.
Sonuç: COVID-19 en sık pnömoni kliniği şeklinde görülse de, COVID-19’u diğer üst/alt solunum yolu viral veya bakteriyel enfeksiyonlarından güvenilir bir şekilde ayıran benzersiz bir klinik özellik yoktur.
References
- 1. Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020;323(13):1239–1242. doi:10.1001/jama.2020.2648.
- 2. Huang, Chaolin, et al. "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China." The lancet 395.10223 (2020): 497-506.
- 3. World Healt Organization. Global Tuberculosis Report 2019, Avaible from: https://www.who.int/tb/global-report-2019.
- 4. Bakanlığı, TC Sağlık. "Tüberküloz tanı ve tedavi rehberi." 2. Baskı Ankara, Mayıs 2019. Avaible from: https://hsgm.saglik.gov.tr/depo/birimler/tuberkuloz_db/haberler/Tuberkuloz_Tani_Ve_Tedavi_Rehberi_/Tuberkuloz_Tani_ve_Tedavi_Rehberi_08.07.2019_Yuksek_KB.pdf.
- 5. Adepoju P. Tuberculosis and HIV responses threatened by COVID-19. Lancet HIV. 2020;7(5):e319-e320. doi:10.1016/S2352-3018(20)30109-0 6. Leung, Ann N. "Pulmonary tuberculosis: the essentials." Radiology 210.2 (1999): 307-322.
- 7. World Health Organization. "The use of loop-mediated isothermal amplification (TB-LAMP) for the diagnosis of pulmonary tuberculosis: policy guidance." (2016).
- 8. Information for Healthcare Professionals about Coronavirus (COVID-19). Updated June 1, 2020. Avaible from: https://www.cdc.gov/coronavirus/2019-nCoV/hcp/index.html
- 9. Wang W, Xu Y, Gao R, et al. Detection of SARS-CoV-2 in Different Types of Clinical Specimens. JAMA.2020;323(18):1843–1844. doi:10.1001/jama.2020.3786.
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Sciences |
| Journal Section | Case Report |
| Authors | |
| Publication Date | March 18, 2021 |
| Submission Date | November 14, 2020 |
| Published in Issue | Year 2021 |