Hantavirüse Bağlı Renal Sendromlu Hemorajik Ateş Sonrası Panhipopitüitarizm

Year 2015, Volume: 6 Issue: 2, 23 - 25, 01.04.2015

Abdülcelil Kayabaş Ali Oğuz Akgün Aynur Atilla Murat Güzel , Ali Kemal Erenler Gül Kefeli Gürses

Abstract

Giriş: Renal Sendromlu Hemorajik Ateş (RSHA), Hantavirüs cinsine
bağlı virüslerce oluşan akut bir viral hastalıktır. Hantavirüsler; ateş,
dolaşım bozukluğu, kanama ve renal yetmezlik ile karekterize bir
hastalık spektrumuna neden olurlar. Hipopitütiarizmin bilinen
nedenleri pitüiter iskemi/infarkt ve nekroz olup klinik özelliklerinin
belirsiz olmasından dolayı genellikle farkedilemezler. Bu yazıda,
acil servise (AS) açıklanamayan hipoglisemi nedeni ile sevkedilen
RSHA sonrası panhipopitüitarizm gelişen 60 yaşına erkek
olgusunu sunduk.
Olgu Sunumu: Biz acil servise RSHA sonrası gelişen
panhipopitutuarizm beraber AS’ye açıklanamayan hipoglisemi
ile başvuran 60 yaşında bir erkek hasta sunduk. Hastanın kan
tetkiklerinde panhipopituitarizm ve anti-Hantavirüs IgG ve IgM
pozitifliği tespit edildi. Hormon replasman tedavisi başlandı ve
hasta ayaktan takibe alınarak tam iyileşme ile taburcu edildi.
Sonuç: Panhipopituitarizm RSHA sonrası çok nadir görülen bir
komplikasyondur. Morbidite ve mortaliteyi azaltmak için; acil tıp,
dahili tıp ve enfeksiyon hastalıkları uzmanları bu komplikasyona
karşı uyanık olmalıdırlar

Keywords

Renal sendromlu hemorajik ateş, panhipopitüitarizm, hantavirüs enfeksiyonu

Panhypopituitarism Following Hemorrhagic Fever with Renal Syndrome Due to Hantavirus

Abstract

Introduction: Hemorrhagic fever with renal syndrome (HFRS) is an acute viral disease caused by viruses that belong to the genus Hantavirus. Hantaviruses produce a spectrum of illness characterized by fever, circulatory collapse, hemorrhages, and renal failure. Pituitary ischemia/infarction and necrosis are known causes of hypopituitarism, often remaining unrecognized because of subtle clinical manifestations. In this report, we present a case of a 60-year-old male patient who was referred to the emergency department (ED) for unexplained hypoglicemia, with panhypopituitarism following HFRS.Case Report: We, hereby, present a 60-year-old male patient admitted to the ED because of unexplained hypoglicemia, with panhypopituitarism following HFRS. Blood tests revealed panhypopituitarism and anti-hantavirus IgM and IgG positivity. Hormone replacement theraphy was initiated, and he was discharged for outpatient follow-up with total recovery.Conclusion: Panypopituitarism is an extremely rare complication of HFRS. Emergency medicine, internal medicine, and infectious diseases specialists should be aware of this complication to reduce mortality and morbidity

Keywords

Hemorrhagic fever with renal syndrome, panhypopituitarism, hantavirus infections

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