A Rare Cause of Rhabdomiyolysis:Sildenafil

Year 2019, Volume: 10 Issue: 4, 98 - 100, 01.10.2019

Selma Şimşek Büşra İhtiyar , Hatice Şeyma Akça , Kamil Kokulu , Serkan Emre Eroğlu

https://doi.org/10.33706/jemcr.508406

Cited By: 1

Abstract

INTRODUCTION

 

Rhabdomyolysis is a syndrome characterized by muscle necrosis
and the release of intracellular muscle components into the bloodstream.

 

CASE
REPORT

 

A
29-year-old male patient presented to the emergency department complaining of
nausea, vomiting and widespread body pain. Physical examination of the agitated
patient who did not want to talk was as followed; Vitals: BP: 115/50, Pulse:
85, Sa02: 95. The patient was conscious, oriented, cooperative and his GCS was 15. Biochemical values
​​in laboratory tests; AST: 224, ALT: 183, LDH: 1273, CK: 33639, and drawn
arterial blood gas were determined as follows: pH: 7.45, hHCO3:18.7, lactate:
2.4. All other laboratory tests were normal. An ECG was performed and it showed
sinus tachycardia. When anamnesis was deepened, he stated that he used Sildenafil and alcohol 24 hours
before and just 3 hours before his admission to the hospital. Patient informed
us that there was no coitus. In the follow-up, the patient who was given
hydration and sodium bicarbonate treatment did not develop dialysis necessity,
his biochemical values ​​showed a rapid decrease of CK level 24000-11000-5000
and the patient was discharged because of the decline of all  his complaints.

DISCUSSION

Rhabdomyolysis is a syndrome characterized by
muscle necrosis and the release of intracellular muscle components into the
bloodstream. The true incidence of Sildenafil-related renal matters is unknown,
since the post-marketing data are very limited. More cases can be detected as
the number of prescription of Sildenafil increases.

 

 

CONCLUSİON

 

Even in patients with nonspecific symptoms, anamnesis (drug use, etc.) should be deepened. Physician awareness is important to prevent possible toxicities and systemic dysfunctions that may be caused by them.

Keywords

rhabdomiyolysis, Sildenafil

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