‘OBSTETRIC MANAGEMENT IN COVID-19 PANDEMIC’
Year 2020,
Volume: 17 Issue: 2, 394 - 399, 25.06.2020
Hüseyin Levent Keskin
,
Şebnem Şen Özyer
,
Dilek Sahin
,
Serpil Ünlü
Namık Özcan
,
Cüneyt Tayman
,
Şule Özel
,
Özlem Moraloğlu Tekin
Abstract
Data related with maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection is limited with few case reports. Number of cases in these reports are few and findings are diverse. Importance of the preventive measures and the treatment protocols in the management of the vulnerable population of pregnant women is increasing. These recommendations are dynamic and will be upgraded as the information related with the epidemiology, pathogenesis, progression and clinical course in pregnant women is gathered.
Key Words: coronavirus, COVID-19, pregnancy, labor, pandemic.
References
- 1-World Health Organization. Director-General's remarks at the media briefing on 2019-nCoV on 11 February 2020. https://www.who.int/dg/speeches/detail/who-director-general-s-remarks-at-the-media-briefingon-2019-ncov-on-11-february-2020 (Accessed on February 12, 2020).
- 2-T.C Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü COVID-19 (SARS-CoV-2 Enfeksiyonu) Rehberi. Bilim Kurulu Çalışması. 12 Nisan 2020. https://covid19bilgi.saglik.gov.tr/depo/rehberler/COVID-19_Rehberi.pdf
- 3-Dashraath P, Jing Lin Jeslyn W, Mei Xian Karen L, Li Min L, Sarah L, Biswas A, Arjandas Choolani M, Mattar C, Lin SL. Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy. Am J Obstet Gynecol. 2020 Mar 23. pii: S0002-9378(20)30343-4.]
- 4-Tang A, Tong ZD, Wang HL, et al. Detection of Novel Coronavirus by RT-PCR in Stool Specimen from Asymptomatic Child, China. Emerg Infect Dis 2020; 26.
- 5-Chen W, Lan Y, Yuan X, et al. Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity. Emerg Microbes Infect 2020; 9:469.
- 6-Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-2019). February 16-24, 2020. http://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf (Accessed on March 04, 2020).
- 7-Uptodate. Coronavirus Disease 2019 (COVID-19): Pregnancy Issues. https://www.uptodate.com/contents/coronavirus-disease-2019-covid-19-pregnancy-issues.
- 8- Rasmussen S, Smulian J, Lednicky J, et al. Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know. Am J Obstet Gynecol 2020 doi: https://doi.org/10.1016/j.ajog.2020.02.017)
- 9-T.C Sağlık Bakanlığı Olası COVID-19 Vaka Sorgulama Kılavuzu. https://covid19bilgi.saglik.gov.tr/depo/formlar/COVID19-VAKA-SORGULAMA-KILAVUZU-A4_1.pdf
- 10- Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, Tao Q, Sun Z, Xia L. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020 Feb 26:200642.
- 11-Moro F, Buonsenso D, Moruzzi MC, et al. How to perform lung ultrasound in pregnant women with suspected COVID-19 infection. Ultrasound Obstet Gynecol. 2020 Mar 24. doi:10.1002/uog.22028.
- 12-Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA.2020 Feb 24)
- 13-Zaigham M, Andersson O. Maternal and Perinatal Outcomes with COVID-19: a systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020 Apr 7.
- 14-Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, Li J, Zhao D, Xu D, Gong Q, Liao J, Yang H, Hou W, Zhang Y. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020 Mar 7;395(10226):809-815.
- 15-Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, Xia S, Zhou W. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020 Feb;9(1):51-60.
- 16-Zhang L, Jiang Y, Wei M, Cheng BH, Zhou XC, Li J, Tian JH, Dong L, Hu RH. Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province. Zhonghua Fu Chan Ke Za Zhi. 2020 Mar 7;55(0):E009.
- 17-Breslin, N., Baptiste, C., Miller, R., Fuchs, K., Goffman, D., Gyamfi-Bannerman, C. D’Alton, M. COVID-19 in pregnancy: early lessons. American Journal of Obstetrics & Gynecology MFM, 2020 Mar 27. https://doi.org/10.1016/j.ajogmf.2020.100111.
- 18-Di Mascio D, Khalil A, Saccone G, et al. Outcome of Coronavirus spectrum infections (SARS, MERS, COVID 1 -19) during pregnancy: a systematic review and metaanalysis. Am J Obstet Gynecol MFM 2020. (Available at: https://www.sciencedirect.com/science/article/pii/S2589933320300379).
- 19-Fan C, Lei D, Fang C, Li C, Wang M, Liu Y, Bao Y, Sun Y, Huang J, Guo Y, Yu Y, Wang S. Perinatal Transmission of COVID-19 Associated SARS-CoV-2: Should We Worry? Clin Infect Dis. 2020 Mar 17. pii: ciaa226.
- 20-Chen S, Huang B, Luo DJ, Li X, Yang F, Zhao Y, Nie X, Huang BX. Pregnant women with new coronavirus infection: a clinical characteristics and placental pathological analysis of three cases]. Zhonghua Bing Li Xue Za Zhi. 2020 Mar 1;49(0):E005.
- 21-Schwartz DA. An Analysis of 38 Pregnant Women with COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes. Arch Pathol Lab Med. 2020 Mar 17.
- 22-Dong L, Tian J, He S, Zhu C, Wang J, Liu C, Yang J. Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn. JAMA. 2020 Mar 26.
- 23-https://www.acog.org/clinical-information/physician-faqs/covid-19-faqs-for-ob-gyns obstetrics (Accessed on April 14, 2020).
- 24-Erdeve Ö, Çetinkaya M, Baş AY, et al. The Turkish Neonatal Society proposal for the management of COVID-19 in the neonatal intensive care unit. Turk Pediatri Ars 2020;55:86–92.
- 25-Interim Considerations for Infection Prevention and Control of Coronavirus Disease 2019 (COVID-19) in Inpatient Obstetric Healthcare Settings https://www.cdc.gov/coronavirus/2019-ncov/hcp/inpatient-obstetric-healthcare-guidance.html (Accessed on April 14, 2020).
- 26-https://www.who.int/news-room/q-a-detail/q-a-on-covid-19-pregnancy-childbirth-and-breastfeeding (Accessed on April 14, 2020).
- 27-Puopolo KM, Hudak ML, Kimberline DW, Cummings J. Initial Guidance: Management of Infants Born to Mothers with COVID-19 https://downloads.aap.org/AAP/PDF/COVID%2019%20Initial%20Newborn%20Guidance.pdf (Accessed on April 14, 2020).
- 28-Poon LC, Yang H, Kapur A, Melamed N, Dao B, Divakar H, David McIntyre H, Kihara AB, Ayres-de-Campos D, Ferrazzi EM, Carlo Di Renzo G, Hod M. Global interim guidance on coronavirus disease 2019 (COVID-19) during pregnancy and puerperium from FIGO and allied partners: Information for healthcare professionals. Int J Gynaecol Obstet. 2020 Apr 4.
- 29-L. C. Poon H. Yang J. C. S. Lee J. A. Copel T. Y. Leung Y. Zhang D. Chen F. Prefumo. ISUOG Interim Guidance on 2019 novel coronavirus infection during pregnancy and puerperium: information for healthcare professionals. Available at: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.22013
COVID-19 PANDEMİSİNDE GEBELİKTE YAKLAŞIM VE YÖNETİM
Year 2020,
Volume: 17 Issue: 2, 394 - 399, 25.06.2020
Hüseyin Levent Keskin
,
Şebnem Şen Özyer
,
Dilek Sahin
,
Serpil Ünlü
Namık Özcan
,
Cüneyt Tayman
,
Şule Özel
,
Özlem Moraloğlu Tekin
Abstract
SARS-CoV-2 (2019-nCoV) ile enfekte gebelerde maternal ve perinatal sonuçlara ait bilgiler birkaç vaka serisinden oluşan oldukça kısıtlı verilerdir. Bu vaka serilerinde olgu sayıları az, bulgular da çok çeşitlidir. Ancak dünya çapında virüsün yayılımının devam etmesi nedeniyle hassas popülasyonlardan biri olan gebelerde hastalığa yaklaşım ve yönetimde, koruyucu önlemlerin ve tedavi protokollerinin önemi giderek artmaktadır. Bu öneriler dinamik olup hastalığın gebe popülasyonda epidemiyolojisi, patogenezi, progresyonu ve klinik seyrine ait bilgiler arttıkça daha da geliştirilecektir.
Anahtar kelimeler: koronavirüs, COVID-19, gebelik, doğum, pandemi
References
- 1-World Health Organization. Director-General's remarks at the media briefing on 2019-nCoV on 11 February 2020. https://www.who.int/dg/speeches/detail/who-director-general-s-remarks-at-the-media-briefingon-2019-ncov-on-11-february-2020 (Accessed on February 12, 2020).
- 2-T.C Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü COVID-19 (SARS-CoV-2 Enfeksiyonu) Rehberi. Bilim Kurulu Çalışması. 12 Nisan 2020. https://covid19bilgi.saglik.gov.tr/depo/rehberler/COVID-19_Rehberi.pdf
- 3-Dashraath P, Jing Lin Jeslyn W, Mei Xian Karen L, Li Min L, Sarah L, Biswas A, Arjandas Choolani M, Mattar C, Lin SL. Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy. Am J Obstet Gynecol. 2020 Mar 23. pii: S0002-9378(20)30343-4.]
- 4-Tang A, Tong ZD, Wang HL, et al. Detection of Novel Coronavirus by RT-PCR in Stool Specimen from Asymptomatic Child, China. Emerg Infect Dis 2020; 26.
- 5-Chen W, Lan Y, Yuan X, et al. Detectable 2019-nCoV viral RNA in blood is a strong indicator for the further clinical severity. Emerg Microbes Infect 2020; 9:469.
- 6-Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-2019). February 16-24, 2020. http://www.who.int/docs/default-source/coronaviruse/who-china-joint-mission-on-covid-19-final-report.pdf (Accessed on March 04, 2020).
- 7-Uptodate. Coronavirus Disease 2019 (COVID-19): Pregnancy Issues. https://www.uptodate.com/contents/coronavirus-disease-2019-covid-19-pregnancy-issues.
- 8- Rasmussen S, Smulian J, Lednicky J, et al. Coronavirus Disease 2019 (COVID-19) and Pregnancy: What obstetricians need to know. Am J Obstet Gynecol 2020 doi: https://doi.org/10.1016/j.ajog.2020.02.017)
- 9-T.C Sağlık Bakanlığı Olası COVID-19 Vaka Sorgulama Kılavuzu. https://covid19bilgi.saglik.gov.tr/depo/formlar/COVID19-VAKA-SORGULAMA-KILAVUZU-A4_1.pdf
- 10- Ai T, Yang Z, Hou H, Zhan C, Chen C, Lv W, Tao Q, Sun Z, Xia L. Correlation of Chest CT and RT-PCR Testing in Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology. 2020 Feb 26:200642.
- 11-Moro F, Buonsenso D, Moruzzi MC, et al. How to perform lung ultrasound in pregnant women with suspected COVID-19 infection. Ultrasound Obstet Gynecol. 2020 Mar 24. doi:10.1002/uog.22028.
- 12-Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA.2020 Feb 24)
- 13-Zaigham M, Andersson O. Maternal and Perinatal Outcomes with COVID-19: a systematic review of 108 pregnancies. Acta Obstet Gynecol Scand. 2020 Apr 7.
- 14-Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, Li J, Zhao D, Xu D, Gong Q, Liao J, Yang H, Hou W, Zhang Y. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020 Mar 7;395(10226):809-815.
- 15-Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, Xia S, Zhou W. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020 Feb;9(1):51-60.
- 16-Zhang L, Jiang Y, Wei M, Cheng BH, Zhou XC, Li J, Tian JH, Dong L, Hu RH. Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province. Zhonghua Fu Chan Ke Za Zhi. 2020 Mar 7;55(0):E009.
- 17-Breslin, N., Baptiste, C., Miller, R., Fuchs, K., Goffman, D., Gyamfi-Bannerman, C. D’Alton, M. COVID-19 in pregnancy: early lessons. American Journal of Obstetrics & Gynecology MFM, 2020 Mar 27. https://doi.org/10.1016/j.ajogmf.2020.100111.
- 18-Di Mascio D, Khalil A, Saccone G, et al. Outcome of Coronavirus spectrum infections (SARS, MERS, COVID 1 -19) during pregnancy: a systematic review and metaanalysis. Am J Obstet Gynecol MFM 2020. (Available at: https://www.sciencedirect.com/science/article/pii/S2589933320300379).
- 19-Fan C, Lei D, Fang C, Li C, Wang M, Liu Y, Bao Y, Sun Y, Huang J, Guo Y, Yu Y, Wang S. Perinatal Transmission of COVID-19 Associated SARS-CoV-2: Should We Worry? Clin Infect Dis. 2020 Mar 17. pii: ciaa226.
- 20-Chen S, Huang B, Luo DJ, Li X, Yang F, Zhao Y, Nie X, Huang BX. Pregnant women with new coronavirus infection: a clinical characteristics and placental pathological analysis of three cases]. Zhonghua Bing Li Xue Za Zhi. 2020 Mar 1;49(0):E005.
- 21-Schwartz DA. An Analysis of 38 Pregnant Women with COVID-19, Their Newborn Infants, and Maternal-Fetal Transmission of SARS-CoV-2: Maternal Coronavirus Infections and Pregnancy Outcomes. Arch Pathol Lab Med. 2020 Mar 17.
- 22-Dong L, Tian J, He S, Zhu C, Wang J, Liu C, Yang J. Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn. JAMA. 2020 Mar 26.
- 23-https://www.acog.org/clinical-information/physician-faqs/covid-19-faqs-for-ob-gyns obstetrics (Accessed on April 14, 2020).
- 24-Erdeve Ö, Çetinkaya M, Baş AY, et al. The Turkish Neonatal Society proposal for the management of COVID-19 in the neonatal intensive care unit. Turk Pediatri Ars 2020;55:86–92.
- 25-Interim Considerations for Infection Prevention and Control of Coronavirus Disease 2019 (COVID-19) in Inpatient Obstetric Healthcare Settings https://www.cdc.gov/coronavirus/2019-ncov/hcp/inpatient-obstetric-healthcare-guidance.html (Accessed on April 14, 2020).
- 26-https://www.who.int/news-room/q-a-detail/q-a-on-covid-19-pregnancy-childbirth-and-breastfeeding (Accessed on April 14, 2020).
- 27-Puopolo KM, Hudak ML, Kimberline DW, Cummings J. Initial Guidance: Management of Infants Born to Mothers with COVID-19 https://downloads.aap.org/AAP/PDF/COVID%2019%20Initial%20Newborn%20Guidance.pdf (Accessed on April 14, 2020).
- 28-Poon LC, Yang H, Kapur A, Melamed N, Dao B, Divakar H, David McIntyre H, Kihara AB, Ayres-de-Campos D, Ferrazzi EM, Carlo Di Renzo G, Hod M. Global interim guidance on coronavirus disease 2019 (COVID-19) during pregnancy and puerperium from FIGO and allied partners: Information for healthcare professionals. Int J Gynaecol Obstet. 2020 Apr 4.
- 29-L. C. Poon H. Yang J. C. S. Lee J. A. Copel T. Y. Leung Y. Zhang D. Chen F. Prefumo. ISUOG Interim Guidance on 2019 novel coronavirus infection during pregnancy and puerperium: information for healthcare professionals. Available at: https://obgyn.onlinelibrary.wiley.com/doi/10.1002/uog.22013