PERİNATAL SONUÇLARI BELİRLEMEDE MSAFP VE ASAFP’NİN YERİ

Year 2020, Volume: 17 Issue: 4, 504 - 510, 31.12.2020

Elif Terzi , Serdar Ceylaner

https://doi.org/10.38136/jgon.735450

Abstract

Amaç: Çalışmamızın amacı maternal serum alfa fetoprotein ve amniyotik sıvı alfa fetoprotein seviyelerinin olumsuz gebelik sonuçları üzerine etkisini değerlendirmektir. Yöntem: Bu çalışmada Zekai Tahir Burak Kadın Hastalıkları Eğitim ve Araştırma Hastanesine müracaat eden, üçlü tarama testi ve sonrasında amniyosentez yapılmış 88 hasta değerlendirildi. Gebelik sonuçları, maternal serum alfa fetoprotein ve amniyotik sıvı alfa fetoprotein sonuçları birlikte analiz edildi. Bulgular: Maternal serum alfa fetoprotein ve amniyotik sıvı alfa fetoprotein düzeyleri arasında korelasyon izlenmedi. Maternal serum alfa fetoprotein düzeyi ile oligohidramnios arasında istatistiksel olarak anlamlı bir ilişki bulunmasına rağmen preeklampsi, preterm eylem, ablasyo plasenta riski açısından anlamlı bir ilişki izlenmemiştir. Amniyotik sıvı alfa fetoprotein düzeyi ile olumsuz gebelik sonuçları arasında istatistiksel anlamlı bir ilişki gözlenmemiştir. Sonuç: Üçlü tarama testi içinde yer alan maternal serum alfa fetoprotein yüksekliği nöral tüp defekti için bir belirteç olmanın haricinde oligohidramnios öngörüsü için de önemli bir anlam içerir. Diğer olumsuz gebelik sonuçları ile ilişkisi tespit edilmemiştir.

Keywords

MSAFP, ASAFP, olumsuz gebelik sonuçları

References

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