Stres ve Kronik Hastalıklar

Year 2023, Volume: 2 Issue: 2, 75 - 84, 30.08.2023

Nuriye Efe Ertürk

https://doi.org/10.5281/zenodo.8296372

Abstract

Stres herhangi bir uyarana karşı organizmanın verdiği yanıttır. Organizma için tehdit oluşturan ve stres yanıtını başlatan uyaranlara stresör denir. Stres akut stres ve kronik stres olmak üzere canlı organizmasında iki etki göstermektedir. Akut stres yaşam ve büyüme için gerekli olan homeostatik dengenin korunmasını sağlayan sağlıklı bir tepkidir. Kronik stres ise stres kaynağının bunaltıcı ve çözülemediği durumlarda ortaya çıkan patalojik bir durumdur. Bu durumda stres yanıtını kontrol eden nöroendokrin bağımlı negatif geri bildirim mekanizması çalışmaz, reseptör dirençleri gelişir ve stresin moleküler mediatörlerinin kandaki seviyeleri yüksek kalır. Sonuç olarak başta bağışıklık sistemi olmak üzere kardiyovasküler, endokrin, renal ve merkezi sinir sistemi hastalıkları gelişir, uzun vadede ise organlar ve dokular üzerinde çoklu hasarlar görülür.

Keywords

Stres, Kronik Hastalıklar, Kronik Stres

References

• Hall J, Hall M. Guyton and Hall Texbook of Medical Physiology. 14. bs. Elsevier; 2020.
• Karadakovan A, Eti Aslan F. Dahili ve Cerrahi Hastalıklarda Bakım. Adana: Adana Nobel Kitabevi; 2010.
• Meaning - Merriam-Webster. Stress Definition [İnternet]. [a.yer 22 Haziran 2023]. Erişim adresi: https://www.merriam-webster.com/dictionary/stress
• TDK. Stres [İnternet]. [a.yer 22 Haziran 2023]. Erişim adresi: https://sozluk.gov.tr/?kelime=stres
• Selye H. Stress and the general adaptation syndrome. Br Med J. 1950;1(4667):1383-92.
• Dragoş D, Tănăsescu MD. The effect of stress on the defense systems. J Med Life. 2010;3(1):10-8.
• Karaçay B. Mutlu Beyin. Ankara: Tübitak Yayınları; 2019.
• Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, vd. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science. 1996;274(5292):1527-31.
• Raleigh ED. The stress response. Occup Health Nurs. 1980;28(12):11-4.
• Segerstrom SC, Miller GE. Psychological stress and the human immune system: A meta-analytic study of 30 years of inquiry. Psychol Bull. 2004;130(4):601-30.
• Pike JL, Smith TL, Hauger RL, Nicassio PM, Patterson TL, McClintick J, vd. Chronic life stress alters sympathetic, neuroendocrine, and immune responsivity to an acute psychological stressor in humans. Psychosom Med. 1997;59(4):447-57.
• Cardel MI, Min YI, Sims M, Musani SK, Dulin-Keita A, DeBoer MD, vd. Association of psychosocial stressors with metabolic syndrome severity among African Americans. Psychoneuroendocrinology. 2018;90:141-7.
• Mariotti A. The effects of chronic stress on health: New insights into the molecular mechanisms of brain–body communication. Future Sci OA. 2015;1(3):FSO23.
• Tuncer M, Küçükusta AR, Topuz E, Özkan A, Sezgin C, Aydın A, vd. Kansere Çözüm Var. 7. İstanbul: Hayykitap; 2015.
• Sirico F, Bianco A, D’Alicandro G, Castaldo C, Montagnani S, Spera R, vd. Effects of physical exercise on adiponectin, leptin, and inflammatory markers in childhood obesity: Systematic review and meta-analysis. Child Obes. 2018;14(4):207-17.
• Hejazi K, Mohammad Rahimi GR, Rosenkranz SK. Effects of exercise training on inflammatory and cardiometabolic risk biomarkers in patients with type 2 Diabetes Mellitus: A systematic review and meta-analysis of randomized controlled trials. Biol Res Nurs. 2023;25(2):250-66.
• Xing H, Lu J, Yoong SQ, Tan YQ, Kusuyama J, Wu XV. Effect of aerobic and resistant exercise intervention on inflammaging of type 2 Diabetes Mellitus in middle-aged and older adults: A systematic review and meta-analysis. J Am Med Dir Assoc. Mayıs 2022;23(5):823-830.e13.
• Zheng G, Qiu P, Xia R, Lin H, Ye B, Tao J, vd. Effect of aerobic exercise on inflammatory markers in healthy middle-aged and older adults: A systematic review and meta-analysis of randomized controlled trials. Front Aging Neurosci. 2019;11:98.
• Tolahunase M, Sagar R, Dada R. Impact of yoga and meditation on cellular aging in apparently healthy individuals: A prospective, open-label single-arm exploratory study. Oxid Med Cell Longev. 2017;2017:7928981.
• Willcox JK, Ash SL, Catignani GL. Antioxidants and prevention of chronic disease. Crit Rev Food Sci Nutr. 2004;44(4):275-95.
• Caimi G, Carollo C, Lo Presti R. Diabetes mellitus: oxidative stress and wine. Curr Med Res Opin. 2003;19(7):581-6.
• Neri S, Signorelli SS, Torrisi B, Pulvirenti D, Mauceri B, Abate G, vd. Effects of antioxidant supplementation on postprandial oxidative stress and endothelial dysfunction: a single-blind, 15-day clinical trial in patients with untreated type 2 diabetes, subjects with impaired glucose tolerance, and healthy controls. Clin Ther. 2005;27(11):1764-73.
• Nishida C, Uauy R, Kumanyika S, Shetty P. The joint WHO/FAO expert consultation on diet, nutrition and the prevention of chronic diseases: process, product and policy implications. Public Health Nutr. 2004;7(1A):245-50.
• Orwelius L, Kristenson M, Fredrikson M, Walther S, Sjöberg F. Hopelessness: Independent associations with health-related quality of life and short-term mortality after critical illness: A prospective, multicentre trial. J Crit Care. 2017;41:58-63.
• Roohafza H, Sattari N, Nouri F, Talaei M, Masoumi G, Sarrafzadegan N, vd. Do any kinds of perceived stressors lead to hypertension? A longitudinal cohort study. Hypertens Res Off J Jpn Soc Hypertens. 2022;45(6):1058-66.
• Shirai K, Iso H, Ohira T, Ikeda A, Noda H, Honjo K, vd. Perceived level of life enjoyment and risks of cardiovascular disease incidence and mortality: the Japan public health center-based study. Circulation. 2009;120(11):956-63.
• Kubzansky LD, Thurston RC. Emotional vitality and incident coronary heart disease: benefits of healthy psychological functioning. Arch Gen Psychiatry. 2007;64(12):1393-401.
• Lundgren O, Garvin P, Nilsson L, Tornerefelt V, Andersson G, Kristenson M, vd. Mindfulness-based stress reduction for coronary artery disease patients: Potential improvements in mastery and depressive symptoms. J Clin Psychol Med Settings. 2022;29(3):489-97.