Investigation of the Effect of Dandelion Plant (Taraxacum Offcinale) on Calcium Oxalate Monohydrate Crystal Growth

Year 2016, Volume: 6 Issue: 3, 97 - 105, 30.09.2016

Emel Akyol

Abstract

The formation of kidney stones is a common diasese. It has accepted that the formation of kidney
stones is a process that consist of nucleation, growth and aggregation of calcium oxalate monohydrate crystals
on epithelial cells at renal papillae in super saturated urine. In spite of the technological developments, the high
recurrence rate of kidney stone formation and the risk factors of all available surgical and medical treatments for
kidney stone disease cause new researches in traditional methods. In this study, the effects of dandelion (Taraxacum
offcinale) plant extract as a natural additive on crystallization of calcium oxalate, which have great importance in
biomineralization, were investigated in vitro.  

Keywords

Additive, calcium oxalate, crystallization, dandelion

Kalsiyum Oksalat Monohidrat Kristal Büyümesine Karahindiba (Taraxacum Offcinale) Bitkisinin Etkisinin İncelenmesi

Abstract

Böbrek taşları günümüzde önemini koruyan, yaygın bir hastalıktır. Böbrek taşı, aşırı doygun ürin
içerisinde kalsiyum oksalat monohidrat kristallerinin renal papillalardaki epitel hücrelerde çekirdeklenme, büyüme
ve çökme aşamalarından oluşan bir kristalizasyon prosesidir. İlerleyen teknolojiye rağmen böbrek taşlarının
tekrarlanabilirliğinin yüksek olması ile tıbbi ve cerrahi tedavilerin yüksek risk faktörleri taşıması geleneksel
yöntemlerde yeni arayışlara sebep olmuştur. Bu çalışmada, biyomineralizasyon açısından oldukça önemli olan
kalsiyum oksalat kristalizasyonuna doğal katkı maddesi olarak Karahindiba (Taraxacum offcinale) bitki ekstraktının
in vitro koşullarda etkileri incelenmiştir  

Keywords

Kalsiyum oksalat, katkı maddesi, karahindiba, kristalizasyon

References

• Akyol E, Oner M, 2007. Inhibition of calcium oxalate monohydrate crystal growth using polyelectrolytes. Journal of Crystal Growth, 307: 137-144.
• Akyol E, Oner M, 2014. Controlling of morphology and polymorph of calcium oxalate crystals by using polyelectrolytes. Journal of Crystal Growth, 401: 260-265.
• Akyol E, Ongun K, Kirboga S, Oner M, 2016. A kinetic study for calcium oxalate crystallization in the presence of Viburnum opulus extract. Biointerface Research In Applied Chemistry, 6: 1059-1063.
• Anonim, 2016. http://www.karahindiba.com/2012/04/karahindiba/ (Erişim tarihi: 06 Mart, 2016).
• Bernard-Michel B, Pons MN, Vivier H, Rohani S, 1999. The study of calcium oxalate precipitation using image analysis. Chemical Engineering Journal, 75: 93-103.
• Cicek F, Ozer D, Ozer A, Özer A, 2007. Low cost removal of reactive dyes using wheat bran. Journal of Hazardous Materials, 146: 408-416.
• Elkady MF, Ibrahim AM, Abd El-Latif MM, 2011. Assessment of the adsorption kinetics, equilibrium and thermodynamics fort he potential removal of reactive red dye using eggshell biocomposite beads. Desalination, 278: 412-423.
• Ivanov IG, 2014. Polyphenols Content and antioxidant activities of Taraxacum offcinale F.H. Wigg (Dandelion) leaves. International Journal of Pharmacognosy and Phytochemical Research, 6: 889-893.
• İleri R, Çakır G, 2006. Bakır iyonlarının (Cu+2) sıvı ortamdan biyosorpsiyonla gideriminin izoterm sabitlerinin Matlab programı ile belirlenmesi. Ekoloji, 59: 8-17.
• Jung T, Kim WS, Choi CK, 2005. Crystal Structure and morphology control of calcium oxalate using biopolymeric additives in crystallization. Journal of Crystal Growth, 279: 154-162.
• Kırboğa S, Oner M, 2010. The role of vinyl sulfonic acid homopolymer in calcium oxalate crystallization. Colloids and Surfaces B: Biointerfaces, 78: 357-362.
• Millan A, Sohnel O, Grases F, 1997. The ınfluence of crystal morphology on the kinetics of growth of calcium oxalate monohydrate. Journal of Crystal Growth, 179: 231-239.
• Miller JD, 1996. Crystallization kinetics of calcium oxalate in simulated urine. The University of Arizona. PhD Thesis, 246p.
• Munoz JA, Valiente M, 2005. Effects of trace metals on the inhibition of calcium oxalate crystallization. Urological Research, 33: 267-272.
• De Oliveira RB, Coelho EB, Rodrigues MR, Costa-Machado ARM, João De Sousa PB, Berretta AA, Bastos JK, 2013. Effect of the copaifera langsdorffi desf. leaf extract on the ethylene glycol-induced nephrolithiasis in rats. Evidence-Based Complementary and Alternative Medicine, 2013:1-10.
• Opalko FJ, Adair JH, Khan SR, 1997. Heterogeneous nucleation of calcium-oxalate trihydrate in artifcial urine by constant composition. Journal of Crystal Growth, 181:410-417.
• Sheehan ME, 1981. The kinetics of crystal growth of calcium oxalate. State University of New York at Buffalo. PhD Thesis, 200p.
• Yu J, Tang H, Cheng B, 2005. Influence of PSSS additive and temperature on morphology and phase structures of calcium oxalate. Journal of Colloid and Interface Science, 288: 407– 411.