Exploring the Impacts of Angelica purpurascens Extracts on Anticholinergic, Antidiabetic, Antibacterial Potential, and Antioxidant Capacity

Year 2024, Volume: 14 Issue: 2, 790 - 804, 01.06.2024

Meryem Topal , Fevzi Topal , Fırat Yılmaz

https://doi.org/10.21597/jist.1411501

Abstract

In Kars-Sarıkamış-Soğanlı, Angelica purpurascens (A. purpurascens) emerges as a promising natural antioxidant source. Extracts from its leaves, branches, and flowers underwent thorough bioanalytical assessments. The leaf extract exhibited the highest concentrations of herbal flavonoids (45.22 µg QE/mg extract) and total phenolics (28.96 µg GAE/mg extract). Branch extracts demonstrated significant enzymatic activity against AChE and BChE with IC50 values of 37.26 mg/mL and 9.08 mg/mL respectively. The flower extract displayed notable antibacterial properties. This study sheds light on the therapeutic potential of A. purpurascens ethanol extracts, suggesting benefits for Alzheimer’s, cell damage-induced diseases, and diabetes mellitus. It pioneers new enzymatic and antioxidant insights and contributes to understanding this abundant Türkiye species. A. purpurascens holds promise for pharmaceutical exploration, offering potential solutions for challenging health conditions

Keywords

Alzheimer’s disease, Angelica purpurascens, Antibacterial, Antioxidant, α-Glycosidase, Cholinesterase

Supporting Institution

This study has been supported by Gümüşhane University Scientific Research Projects Coordination Department (Project No: 22.B0225.02.01).

Project Number

22.B0225.02.01

Thanks

This study has been supported by Gümüşhane University Scientific Research Projects Coordination Department (Project No: 22.B0225.02.01).

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