Sleep Disorder During SARS-Cov-2 Infection: A Case Report

Year 2021, Volume: 7 Issue: 1, 18 - 22, 30.09.2021

Erkut Etçioğlu , İhsan Sarıkaya , Abdülkadir Aydın

Abstract

In the course of COVID-19 disease, a wide variety of organ and system involvements have been reported, as well as neurological involvement. Neurological picture caused by the disease include loss of taste and smell, sleep disorders, headache and meningitis. It has been suggested that sleep disorders may occur with the effect of stressor factors and immunological mechanisms that develop in various infection processes. In this article, we present a case who had no sleep disorder before, who described severe sleeplessness that started in the course of SARS-CoV-2 infection and returned to her old sleep pattern after COVID-19 treatment.

Keywords

Sleep Disorder, Neurological Symptoms, COVID-19, SARS-CoV-2

SARS-CoV-2 Enfeksiyonu Seyrinde Gelişen Uyku Bozukluğu: Olgu Sunumu

Abstract

COVID-19 hastalık seyrinde çok çeşitli organ ve sistem tutulumları ile birlikte nörolojik tutulumlar da bildirilmiştir. Hastalığın neden olduğu nörolojik tablolarda tat ve koku kaybı, uyku bozukluğu, baş ağrısı ve menenjit yer almaktadır. Stresör faktörlerin ve çeşitli enfeksiyon süreçlerinde gelişen immünolojik mekanizmaların etkisi ile uyku bozukluklarının oluşabileceği öne sürülmüştür. Bu yazımızda daha önce hiçbir uyku sorunu olmayan, SARS-CoV-2 enfeksiyonu seyrinde başlamış şiddetli uykusuzluk tarifleyen ve COVID-19 tedavisi sonrası eski uyku paternine geri dönen bir olgu sunulmaktadır.

Keywords

Uyku Bozukluğu, Nörolojik Semptomlar, COVID-19, SARS-CoV-2

References

• World Health Organization (WHO). WHO Coronavirus Disease (COVID-19) Dashboard. https://covid19.who.int. Erişim: 12.12.2020.
• Hassan SA, Sheikh FN, Jamal S, et al. Coronavirus (COVID-19): a review of clinical features, diagnosis, and treatment. Cureus 2020;12.
• Gutiérrez-Ortiz C, Méndez-Guerrero A, Rodrigo-Rey S, et al. Miller Fisher syndrome and polyneuritis cranialis in COVID-19. Neurology. 2020 Aug 4;95(5):e601-e605. doi: 10.1212/WNL.0000000000009619.
• Asif N, Iqbal R, Nazir CF. Human immune system during sleep. Am J Clin Exp Immunol. 2017;6(6):92-96. Published 2017 Dec 20.
• Etçioğlu E, Aydın A, Sevimli Dikicier B. Döküntünün Eşlik Ettiği SARS-CoV-2 Enfeksiyonu: Olgu Sunumu. J Biotechnol and Strategic Health Res. 2020;4(2):173-177.
• Besedovsky L, Lange T, Haack M. The Sleep-Immune Crosstalk in Health and Disease. Physiol Rev. 2019;99(3):1325-1380. doi:10.1152/physrev.00010.2018
• Ibarra-Coronado EG, Pantaleón-Martínez AM, Velazquéz-Moctezuma J, et al. The Bidirectional Relationship between Sleep and Immunity against Infections. J Immunol Res. 2015;2015:678164. doi: 10.1155/2015/678164.
• Tony AA, Tony EA, Ali SB, et al. COVID-19-associated sleep disorders: A case report. Neurobiol Sleep Circadian Rhythms. 2020;9:100057. doi:10.1016/j.nbscr.2020.100057.
• Das G, Mukherjee N, Ghosh S. Neurological Insights of COVID-19 Pandemic. ACS Chem Neurosci. 2020 May 6;11(9):1206-1209. doi: 10.1021/acschemneuro.0c00201.
• Lasselin J, Ingre M, Regenbogen C, et al. Sleep during naturally occurring respiratory infections: A pilot study. Brain Behav Immun. 2019 Jul;79:236-243. doi: 10.1016/j.bbi.2019.02.006.