Diyabetik maküla ödeminde arka vitreus dekolmanının rolü

Year 2022, Volume: 3 Issue: 4, 322 - 327, 26.12.2022

Ayşe Tüfekçi Balıkçı , Nurten Unlu , Sunay Duman

https://doi.org/10.47582/jompac.1188838

Abstract

Giriş: Bu çalışmada diyabetik retinopatisi olan olgularda total arka vitreus dekolmanı (PVD) varlığının maküla ödemi oluşumu üzerine olan etkisini diğer risk faktörleriyle birlikte değerlendirmeyi amaçladık
Gereç ve Yöntem: Diyabetik retinopatili 103 hastanın 166 gözü prospektif olarak çalışma kapsamına alındı. Maküla ödemi olan 58 hastanın 96 gözü (grup 1) ve maküla ödemi olmayan 45 hastanın 70 gözü (grup2) PVD varlığı ve diğer risk faktörleri açısından karşılaştırıldı.
Bulgular: Yaş ortalamaları 1.grupta 61,8 ±5,5, 2.grupta 63,6±7,2 idi (p>0,05). İki grupta kadın/erkek oranı ve diyabet süreleri açısından anlamlı fark yoktu. Maküla ödemi olan 96 gözün 11’inde (%11,45), maküla ödemi olmayan 70 gözün 8’inde (%11,42) PVD bulundu. Her iki grupta PVD oranları açısından istatistiksel olarak anlamlı bir fark saptanmadı (χ2=0,9953, p>0,05). İki grupta proliferatif diyabetik retinopati oranları, hipertansiyon ve proteinüri varlığı, açlık kan şekeri, üre, kreatinin ve HbA1c oranları karşılaştırıldı. İki grup arasında anlamlı fark saptanmadı (p>0,05). İnsülin kullanma oranı 2.grupta fazla bulundu (p<0,001).
Sonuç: Çalışmamızda, maküla ödemi olan ve maküla ödemi olmayan gruplarda PVD oranları arasında anlamlı fark saptanmadı. Bu nedenle PVD varlığının maküla ödemine karşı koruyucu bir faktör olmadığı kanısına vardık. Diyabetik maküla ödeminin patogenezi multifaktöriyeldir. Arka vitreus dekolmanının maküla ödemi üzerindeki rolünü anlamak için daha geniş çaplı ve maküla ödemini uzun süre takibe alan çalışmalar yapılmalıdır

Keywords

Diyabetik retinopati, maküla ödemi, arka vitreus dekolmanı

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The role of the posterior vitreous detachment in diabetic macular edema

Abstract

Introduction: In this study, we aimed to evaluate the effect of the presence of total posterior vitreous detachment (PVD) on the formation of macular edema in patients with diabetic retinopathy together with other risk factors.
Material and Method: 166 eyes of 103 patients with diabetic retinopathy were prospectively included in the study. 96 eyes of 58 patients with macular edema (group 1) and 70 eyes of 45 patients without macular edema (group 2) were compared in terms of the presence of PVD and other risk factors.
Results: The mean age was 61.8±5.5 in the first group and 63.6±7.2 in the second group (p> 0.05). There was no significant difference between the two groups in terms of female/male ratio and duration of diabetes. PVD was found in 11 (11.45%) of 96 eyes with macular edema and 8 (11.42%) of 70 eyes without macular edema. There was no statistically significant difference in terms of PVD rates in both groups (χ2 = 0.9953, p> 0.05). Proliferative diabetic retinopathy rates, presence of hypertension and proteinuria, fasting blood glucose, urea, creatinine and HbA1c rates were compared in the two groups. Insulin use rate was higher in the second group (p <0.001).
Conclusion: In our study, there was no significant difference between PVD rates in the groups with and without macular edema. Therefore, we concluded that the presence of PVD is not a protective factor against macular edema. Pathogenesis of diabetic macular edema is multifactorial. In order to understand the role of posterior vitreous detachment on macular edema, larger-scale studies that follow macular edema for a long time should be done.

Keywords

iabetic retinopathy, macular edema, posterior vitreous detachment

Project Number

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