Macroaggregated Albumin (MAA): Production, Size Optimization, Eu(III) and Tb(III) Complexes

Year 2021, Volume: 8 Issue: 1, 209 - 216, 28.02.2021

Burcu Uçar , Tayfun Acar

https://doi.org/10.18596/jotcsa.808636

Cited By: 5

Abstract

Herein, the synthesis of the macroaggregated albumin particles was carried out under different conditions for the size optimization that can be used in Magnetic resonance and fluorescence imaging. The size distribution analysis was performed with the Mastersizer and optimized MAA had 31.57 µm size and 0.36 PDI value. Morphological analysis was done with SEM. EDX and FT-IR analyzes were performed by forming Eu3+ and Tb3+ complexes with optimized MAA. MAA complexes that can be used in lungs and liver imaging have been successfully obtained.

Keywords

MAA, Eu(III) complexes, Tb(III) complexes, Magnetic resonance imaging, Fluorescence imaging

Thanks

The authors are grateful to Prof Dr. Tevfik Fikret CERMIK and Doç. Dr. Esra ARSLAN for critical revisions of the study. The authors also would like to thank M. Beşir ARVAS for all his support.

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