Süt İneklerinde Propilen Glikol ve Gliserol Kullanımının Betahidroksibutirik Asit, Esterleşmemiş Yağ Asitleri ve Vücut Kondüsyon Skoru Üzerine Etkileri

Year 2023, Volume: 42 Issue: 1, 48 - 54, 01.07.2023

Tolga Altaş , Ramazan Yıldırım

https://doi.org/10.30782/jrvm.1224380

Abstract

Bu çalışmanın amacı; geçiş döneminde görülen negatif enerji dengesi problemine, glikoz prekürsörlerinin kan betahidroksibutirik asit
(BHBA), Esterleşmemiş yağ asitleri (NEFA) ve vücut kondisyon skoru (VKS) üzerindeki etkilerini incelemektir. Bu çalışmada en az bir
doğum yapmış, 60 Holstein ırkı süt ineği kullanılmıştır. Hayvanlar 20’şer adetten oluşan 3 gruba ayrılmıştır. Gliserol (G) grubundaki hayvanlara
sabah yemlemesinden sonra günde 1 öğün pompayla 450 ml gliserol, Propilen Glikol (PG) grubuna 300 ml propilen glikol içirilmiştir.
Kontrol (K) grubundaki hayvanlara herhangi bir uygulama yapılmamıştır. Hayvanların süt verimleri deneme süresince günlük takip edilmiştir.
Laktasyonun 100. gününe kadar her hafta art arda iki gün tüm sığırlardan süt numunesi toplanarak süt analizleri yapılmıştır. Beta hidoksi-
bütirik asit (BHBA) ve esterleşmemiş yağ asitleri (NEFA) testleri için kan örnekleri doğum öncesi 1, doğum sonrası 0, 1, 2 ve 3. haftalarda
alınarak ticari kitlerle analizleri yapılmıştır. İneklerden alınan kan numunelerinden BHBA, NEFA ve VKS seviyelerinde gruplar arasında
farklılık saptanmamıştır. Bu çalışmadan G ve PG gibi glikoz prokürsörlerinin özellikle geçiş dönemindeki ineklerde kan BHBA, NEFA ve
Vücut kondüsyon skorları üzerine herhangi bir etki yaratmadığı sonucu çıkarılabilir.

Keywords

Propilen Glikol, Gliserol, Geçiş Dönemi, Negatif Enerji Dengesi

The Effects of Using Propylene Glycol and Glycerol on BHBA, NEFA and Body Condition Score in Dairy Cows

Abstract

The aim of this study; The aim of this study is to examine the effects of glucose precursors on the negative energy balance problem seen in the
transition period, on blood BHBA, NEFA and body condition score (BCS). In the study, 60 Holstein dairy cows with at least one birth were
used. The animals were divided into 3 groups of 20 each. Animals in the glycerol (G) group were given 450 ml of glycerol with a pump once
a day after morning feeding, and 300 ml of propylene glycol in the Propylene Glycol (PG) group. No application was made to the animals
in the control (K) group. For metabolic profile tests such as beta hydroxy-butyric acid (BHBA) and non-esterified fatty acids (NEFA), blood
samples were taken at prenatal 1, postnatal 0, 1, 2 and 3 weeks and analyzed with commercial kits. There was no difference between the groups
in BHBA, NEFA and VKS levels from blood samples taken from cows. It was concluded that the using glucose precursor which are propylene
glycol and glycerol during the transiiton period there was no significant effect on BHBA, NEFA and BCS in dairy cows.

Keywords

Propylene Glikol, Gliycerol, Transition Period, Negative Energy Balance, Propilen Glikol, Gliserol, Geçiş Dönemi, Negatif Enerji Dengesi

References

• Meral Y, Kara Ç (2013). Geçiş Dönemindeki Süt Sığırlarında Karaciğer Yağlanması ve Kolinin Önemi. J Res Vet Med. 2013, 39-45. Hayırlı A, Kaynar Ö, Serbester U. Hepatik Lipidoz ve Ketozis. J Vet Sci. 2012; 38-69.
• Herdt, Thomas H. "Ruminant adaptation to negative energy balance: Influences on the etiology of ketosis and fatty liver." Veterinary Clinics of North America: F Anim Prac. 16.2 (2000): 215-230.
• Butler, W. R. "Nutritional interactions with reproductive performance in dairy cattle." A. rep Sci. 2000; 60: 449-457.
• Van Knegsel, A. T. M., et al. "Ketone body concentration in milk determined by Fourier transform infrared spectroscopy: Value for the detection of hyperketonemia in dairy cows."J Dairy Sci. 2010;93.(7): 3065-3069.
• Townsend, Jonathan. "Cowside tests for monitoring metabolic disease." Proceedings of the 20th Annual Tri-State Dairy Nutrition Conference, Grand Wayne Center, Fort Wayne, Indiana, USA, 19-20 April, 2011. Ohio State University, 2011.
• Drackley, James K., et al. "Physiological and pathological adaptations in dairy cows that may increase susceptibility to periparturient diseases and disorders."J. of Anim Sci. 2005;4.4: 323-344.
• Hayirli, A., et al. "Effect of chromium supplementation on production and metabolic parameters in periparturient dairy cows." J Dairy Sci. 2001;84(5):1218-1230.
• NRC. National Research Council. Nutrient Requirements of Dairy Cattle, 7th ed,. National Academies Press: Washington, DC, USA, 2001.
• AOAC. Official methods of analysis. 16th edn. Association of Official Analytical Chemists, Virginia, USA, 1995.
• Van Soest, P. J. "Carbohydrate methodology, metabolism, and nutritional implications in dairy cattle: Methods for dietary fiber, neutral detergent fiber, and nonstarch polysaccharides in relation to animal nutrition." J. Daily Sci. 1991;74: 3583-3597.
• LeBlanc, Stephen. "Monitoring metabolic health of dairy cattle in the transition period." J. Reprod. Dev. 2010;56.S: S29-S35.
• Wildman, E. E., et al. "A dairy cow body condition scoring system and its relationship to selected production characteristics." J Dairy Sci.1982;63.3: 495-501.
• Sauer, F. D., J. D. Erfle, and L. J. Fisher. "Propylene glycol and glycerol as a feed additive for lactating dairy cows: an evaluation of blood metabolite parameters." Can. J. Anim. Sci 1973;53.2: 265-271.
• Lomander, H., et al. "Supplemental feeding with glycerol or propylene glycol of dairy cows in early lactation—Effects on metabolic status, body condition, and milk yield." " J Dairy Sci. 2012;95.5: 2397-2408.
• Fisher, L. J., J. D. Erfle, and F. D. Sauer. "Preliminary evaluation of the addition of glucogenic materials to the rations of lactating cows." Can. J. Anim. Sci.1971;51.3: 721-727.
• Pieper, R., et al. "Ketoseprophylaxe bei kühen mit hohenmilchleistungen. 4." Aufl. Lübke Druck & Neuruppin 2005: 1-37.
• Christensen, Jens O., et al. "Effect of method of delivery of propylene glycol on plasma metabolites of feed-restricted cattle."J Dairy Sci.1997;80.3: 563-568.
• Moallem, U., et al. "Effects of peripartum propylene glycol or fats differing in fatty acid profiles on feed intake, production, and plasma metabolites in dairy cows." J Dairy Sci. 2007;90.8: 3846-3856.
• Chung, Y-H., I. D. Girard, and G. A. Varga. "Effects of feeding dry propylene glycol to early postpartum Holstein dairy cows on production and blood parameters." animal 2009;3.10: 1368-1377.
• Pickett, M. M., M. S. Piepenbrink, and T. R. Overton. "Effects of propylene glycol or fat drench on plasma metabolites, liver composition, and production of dairy cows during the periparturient period." J Dairy Sci. 2003;86.6: 2113-2121.
• Drackley, James K. "Nutritional Management of Transition Dairy Cows." American Association of Bovine Practitioners Proceedings of the Annual Conference. 2011.
• Butler, S. T., Susanne H. Pelton, and W. R. Butler. "Energy balance, metabolic status, and the first postpartum ovarian follicle wave in cows administered propylene glycol." J Dairy Sci. 2006;89.8: 2938-2951.
• Bodarski, R., et al. "The changes of metabolic status and lactation performance in dairy cows under feeding TMR with glycerin [glycerol] supplement at periparturient period." Electronic Journal of Polish Agricultural Universities. Series Animal Husbandry 4.08 (2005).
• Osman, M. A., et al. "Acute metabolic responses of postpartal dairy cows to subcutaneous glucagon injections, oral glycerol, or both." J Dairy Sci.2008;91.9: 3311-3322.
• DeFrain, J. M., et al. "Feeding glycerol to transition dairy cows: effects on blood metabolites and lactation performance."J Dairy Sci. 2004;87.12: 4195-4206.
• Kupczyński, Robert, Rafał Bodarski, and Maciej Adamski. "Influence of glycerin on content of chosen biochemical blood parameters of cows in transition period." Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine 14.2 (2011).
• Hoedemaker, M., et al. "Peripartal propylene glycol supplementation and metabolism, animal health, fertility, and production in dairy cows."J Dairy Sci.2004;87.7: 2136-2145.
• Butler, S. T., Susanne H. Pelton, and W. R. Butler. "Energy balance, metabolic status, and the first postpartum ovarian follicle wave in cows administered propylene glycol." J Dairy Sci. 2006;89.8: 2938-2951.
• Burhans, W. S., E. A. Briggs, J. A. Rathmacher, and A. W. Bell. "Glucogenic supplementation does not reduce body tissue protein degradation in periparturient dairy cows." J Dairy Sci. 80.suppl. 1997.1: 167.
• Liu, Q., et al. "Effects of feeding propylene glycol on dry matter intake, lactation performance, energy balance and blood metabolites in early lactation dairy cows." animal 2009;3.10: 1420-1427.
• Goff, Jesse P., and Ronald L. Horst. "Oral glycerol as a gluconeogenic precursor in the treatment of ketosis and fatty liver." Acta. Vet. Scand. Suppl. 2003;44.1: 1-2.. 98.
• Osborne, V. R., et al. "Effects of supplementing glycerol and soybean oil in drinking water on feed and water intake, energy balance, and production performance of periparturient dairy cows."J Dairy Sci. 2009;92.2: 698-707.
• Ogborn, Kathleen. "Effects of method of delivery of glycerol on performance and metabolism of dairy cows during the transition period." (2006).
• Juchem, S. O., et al. "Production and blood parameters of Holstein cows treated prepartum with sodium monensin or propylene glycol." J Dairy Sci. 2004;87.3: 680-689.
• Nielsen, Nicolaj Ingemann, and Klaus Lønne Ingvartsen. "Propylene glycol for dairy cows: A review of the metabolism of propylene glycol and its effects on physiological parameters, feed intake, milk production and risk of ketosis." Anim. Feed Sci. And Tech 2004;115.3-4: 191-213.
• Donkin, Shawn S., and Perry Doane. "Glycerol as a feed ingredient in dairy rations." Proceedings of the 2007 Tri-State Dairy Nutrition Conference, Fort Wayne, Indiana, USA, 24-25 April, 2007. Ohio State University, 2007.