Evaluation of Gastrointestinal Polyps According to Their Size, Localization and Histopathologic Types; Annual Period

Year 2018, Yıl: 2018 Ek Sayı: 1, 13 - 21, 01.01.2018

Havva Erdem

https://doi.org/10.5505/kjms.2017.07269

Abstract

Aim: It was aimed to document gastrointestinal system polyps and evaluated with respect to their frequency, size, anatomic location and histopathologic features. 
Material and Method: 56 gastrointestinal polyps that were histopathologically diagnosed during the period 2014-2015 were included in the study. Polyps were noted according to their localization, age, gender, size and histopathologic types. 
Results: 59 % of the patients were males and 41% of the patients were females. Their mean age was 61.7 years. The mean diameter of the adenomatous polyps was 10.12 mm. The mean diameter of the hyperplastic polyps was 5.7 mm.18 cases were diagnosed as tubular adenomas(32 %). 16 cases were diagnosed as tubulovillous adenomas (28%), 21 cases were diagnosed as hyperplastic polyps (37.5%), 1 case was diagnosed as mixed polyps,1 case was diagnosed as juvenile polyps. 10 cases of hyperplastic polyps were localized sigmoid colon (% 47.6) and 6 cases were localized rectum (% 28.5). 16 cases of adenomatous polyps were localized sigmoid colon (% 47). Ages ranged from 4 to 84 years were diagnosed as all polyps. Gender were 33 men and 23 female. 
Conclusion: In this study, it was showed that the oldest groups of tubulovillous adenoma, the most common groups of hyperplastic polyps, the most common gender of male, the most common location of sigmoid colon.

Keywords

Gastrointestinal polyps, histologic types, localization, size, age

Gastrointestinal Poliplerin Boyutları, Lokalizasyonu ve Histopatolojik Tiplerine Göre Değerlendirilmesi; Bir Yıllık Periyod

Abstract

Amaç: Bu çalışmada, gastrointestinal sistem poliplerini sıklığı, büyüklüğü, anatomik lokalizasyonu ve histopatolojik özellikleri açısından değerlendirilmesi amaçlandı. 
Materyal ve Metot: 2014-2015 yılları arasında histopatoloji tanısı konulan 56 adet polip lokalizasyonları, çapları, cinsiyet, yaş ve histopatolojik tiplerine göre kaydedildi. 
Bulgular: Hastaların% 59'u erkek ve % 41'i kadındır. Tüm vakaların yaş ortalaması 61.7 idi. Adenomatöz poliplerin ortalama çapı 10.12 mm idi. Hiperplastik poliplerin ortalama çapı 5.7 mm idi.18 vakaya tübüler adenom (% 32), 16 vakaya tubulovillöz adenom (% 28) tanısı konuldu, 21 vakaya hiperplastik polip (% 37.5), 1 vaka mikst polip, 1 vakaya ise jüvenil polip tanısı konuldu.Hiperplastik poliplerin 10’u (% 47.6) sigmoid kolona lokalize ve 6’sı rektuma (% 28.5) lokalizeydi.Adenomatöz poliplerin 16’sı sigmoid kolona (% 47) lokalizeydi. Tüm poliplerin yaş dağılımı, 4 ile 84 arasında değişmekteydi. Cinsiyet dağılımı ise, 33’ü erkek ve 23’ü kadındı.
Sonuç: Bu çalışmada, tubulovillöz adenomların yaşlılarda sık olduğu, hiperplastik poliplerin, erkek cinsiyetin ve sigmoid kolon yerleşiminin en yaygın olduğu gösterilmiştir.

Keywords

Gastrointestinal polipler, histolojik tipleri, lokalizasyon, boyut, yaş

References

• 1- Lau CF, Hui PK, Mak KL et al. Gastric polypoid lesions-illustrative cases and literature review. Am J Gastroenterol 1998; 93: 2559-64
• 2- Silverstein FE, Tytgat GNJ. Stomach II: tumors and polyps. In: Silverstein FE, Tytgat GNJ, eds. Gastrointestinal Endoscopy. London: Mosby; 1997:147-80.
• 3- Rafiul Sameer Islam, Neal C. Patel, Dora Lam-Himlin, Cuong C. Nguyen. Gastric Polyps: A Review of Clinical, Endoscopic, and Histopathologic Features and Management Decisions. Gastroenterol Hepatol (N Y). 2013; 9(10): 640–51.
• 4- Do Youn Park and Gregory Y. Lauwers. Gastric Polyps: Classification and Management. Arch Path Lab Med 2008;132(4):633-640.
• 5- Roni Atalay, Tevfik Solakoğlu, Sevil Özer Sarı et al. Evaluation of gastric polyps detected by endoscopy: A single-center study of a fouryear experience in Turkey. Tr J Gastroenterol 2014; 25: 370-3
• 6- Noam Shussman, Steven D. Wexner. Colorectal polyps and polyposis syndromes. Gastroenterology Report 2014; 2(1):1–15
• 7- Snover D, Ahnen DJ, Burt RW, Odze RD. Serrated polyps of the colon and rectum and serrated polyposis. In: Bosman FT, Carneiro F, Hruban RH, Theise ND, eds. WHO Classification of Tumours of the Digestive System. 4th ed. Lyon, France: IARC Press; 2010:160–65.
• 8- Williams AR, Balasooriya BA, Day DW. Polyps and cancer of the large bowel: a necropsy study in Liverpool. Gut 1982; 23: 835–42.
• 9- Konishi F, Morson BC. Pathology of colorectal adenomas: A colonoscopic survey. J Clin Pathol 1982; 35: 830-41.
• 10- O'Brien MJ, Winawer SJ, Zauber AG et al. The National Polyp Study: Patient and polyp characteristics associated with highgrade dysplasia in colorectal adenomas. Gastroenterol 1990; 98: 371-9.
• 11- Altınparmak E, Sezgin O, Parlak E, Altıntaş E. Colorectal polyps ‘The Yüksek İhtisas experience’. Tr J Gastroenterol 2001; 12: 49-52.
• 12- Muto T, Bussey HJR, Morson BC. The evolution of cancer of the colon and rectum. Cancer 1975: 36; 2251-70.
• 13- Ahmet Tarık Eminler, Mustafa Sakallı, Kader Irak et al. Gastroenteroloji ünitemizdeki kolonoskopik polipektomi sonuçlarımız. Akademik Gastroenterol Derg 2011; 10(3): 112-5.
• 14- Yasemin Dölek, Yasemin Yuyucu Karabulut , Firdevs Topal, Nazmiye Kurşun. Evaluation of gastrointestinal polyps according to their size, localization and histopathologic types. Endoskopi Derg 2013; 21 (2) : 31-5
• 15-Sangeetha N Kalimuthu, Adeline Chelliah, Runjan Chetty. From traditional serrated adenoma to tubulovillous adenoma and beyond. World J Gastrointest Oncol. 2016; 8(12): 805–09.
• 16- J Pohl. Hyperplastic Polyposis Syndrome. Video Journal and Encyclopedia of GI Endoscopy. 2013; 1 (2): 370–71.
• 17- Vatn M, Stalsberg H. The prevalence of polyps of the large intestine in Oslo: an autopsy study. Cancer 1982;49:819–25.
• 18- Lieberman D, Weiss D, Bond J et al. Use of colonoscopy to screen asymptomatic adults for colorectal cancer. N Engl J Med 2000;343:162–8.
• 19- Gibbs DH, Opelka FG, Beck DE, Hicks TC, Timmcke AE, Gathright JB Jr. Postpolypectomy colonic hemorrhage. Dis Colon Rectum 1996;39:806-10.
• 20- Bond JH. Clinical evidence for the adenoma-carcinoma sequence, and the management of patients with colorectal adenomas. Semin Gastrointest Dis 2000;11:176-84.
• 21- Atkin WS, Morson BC, Cuzick J. Longterm risk of colorectal cancer after excision of rectosigmoid adenomas. N Engl J Med 1992;326:658-62.
• 22- Oberhuber G, Stolte M. Gastric polyps: an update of their pathology and biological significance. Virchows Arch 2000; 437: 581- 90.
• 23- Morais DJ, Yamanaka A, Zeiture JM, Andreollo NA. Gastric polyps: a retrospective analysis of 26.000 digestive endoscopies. Arq Gastroenterol 2007; 44: 14-7.
• 24- Archimandritis A, Spiliadis C, Tzivras M et al. Gastric epithelial polyps: aretrospective endoscopic study of 12974 symptomatic patients. Ital J Gatroenterol 1996; 28: 387-90.
• 25- Gencosmanoglu R, Sen-Oran E, KurtkayaYapicier O, Avsar E, Sav A, Tozun N. Gastric polypoid lesions: analysis of 150 endoscopic polypectomy specimens from 91 patients. World J Gastroenterol 2003; 9: 2236-9.
• 26- Debongnie JC. Gastric polyps. Acta Gastroenterol Belg 1999; 62: 187-9.
• 27- Davaris P, Petraki K, Archimandritis A, Haritopoulos N, Papacharalampous N. Mucosal hyperplastik polyps of the stomach. Do they have any potential to malignancy? Pathol Res Pract 1986; 181: 385-9.
• 28- Nik Ritza Kosai, Hardip Singh Gendeh, Abdul Rashid Norfaezan, Jamin Razman, Paul Anthony Sutton, Srijit Das. Possible neoplastic transformation within gastric hyperplastic polyp. Application of endoscopic polypectomy. Surg Endosc 1995; 9: 714-8.29
• 29- Botteri E, Iodice S, Raimondi S, Maisonneuve P, Lowenfels AB. Cigarette smoking and adenomatous polyps: a metaanalysis. Gastroenterol 2008 ;134(2):388-95.