Relationship Between Epicardial Adipose Tissue Thickness and Fragmented QRS

Year 2017, Volume: 20 Issue: 3, 206 - 209, 03.12.2017

Ali Rıza Akyüz , Selim Kul Muhammet Raşit Sayın Turhan Turan Levent Korkmaz

Abstract

Introduction:
Fragmented
QRS (fQRS) on a 12-lead electrocardiogram (ECG) has been demonstrated as a
marker of myocardial fibrosis. The main purpose of present study was to
investigate the association between epicardial adipose tissue (EAT) and fQRS.

Patients
and Methods: Study population consisted of 151 patients had fQRS
detected on a routine 12-lead ECG and 114 controls without fQRS. EAT was
assessed by measuring epicardial fat thickness with echocardiography. fQRS was
defined by the presence of various RSR’ patterns included an additional R wave
(R), notching of the R wave, notching of the downstroke or upstroke of the S
wave, or the presence of > 1 R in 2 contiguous leads corresponding to a major
coronary artery territory.

Results: Patients
with fQRS had higher EAT values than those without fQRS (5.9 ± 2.7, 3.8 ± 2.3,
p< 0.001). Univariate analyses demonstrated significant association between
fQRS and EAT (p< 0.001), hypertension (p= 0.015). Binary logistic regression
analysis revealed EAT (95% confidence interval [CI] 1.053-1.938, p= 0.022) and
total cholesterol (95% CI: 1.001-1.030, p= 0.037) as independent determinants
of fQRS.

Conclusion: In the present study, we
found higher amounts of EAT in subjects with fQRS. In addition, presence of
fQRS was independently associated with EAT.

Keywords

fQRS, epicardial adipose tissue, myocardial fibrosis

Epikardiyal Yağ Dokusu Kalınlığı ve Parçalı QRS Arasındaki İlişki

Abstract

Giriş: On iki kanallı elektrokardiyografi (EKG)’de tespit edilen
parçalı QRS (pQRS)’nin  miyokart
fibrozunun bir belirteci olduğu gösterilmiştir. Bu çalışmanın amacı epikardiyal
yağ dokusu kalınlığı (EYK) ile pQRS arasındaki ilişkiyi incelemektir.

Hastalar ve Yöntem: Çalışmaya kardiyoloji polikliniğimize
müracaat edip rutin eloktrokardiyografik incelemede pQRS’si olan 151 hasta ve
kontrol grubu olarak pQRS’si olmayan 114 hasta alındı. EYK ekokardiyografide
hesaplandı. Parçalanmış QRS birbirini takip eden iki EKG derivasyonunda ilave R
dalgası (R’) veya R veya S dalgasında çentiklenme veya bölünme varlığı olarak
alındı. 

Bulgular: pQRS olan hastalarda EYK değerleri daha yüksekti  (5.9 ± 2.7, 3.8 ± 2.3, p< 0.001). Tek
değişkenli analiz  EYK ile pQRS (p<
0.001) ve hipertansiyon (p= 0.015)  arasında
anlamlı bir ilişki olduğunu göstermiştir. Binary lojistik regresyon analizi,
EYK [%95 güven aralığı (GA) 1.053-1.938, p= 0.022] ve total kolesterolü (%95
GA: 1.00-1.030, p= 0.037)  pQRS‘nin
bağımsız bir belirleyicisi olarak ortaya koydu.

Sonuç: Bu çalışmada, pQRS’li
hastalarda EYK’yi artmış olarak  tespit
ettik. Buna ek olarak EYK, pQRS’nin güçlü ve bağımsız bir belirteci olarak
bulunmuştur.

Keywords

Parçalı QRS, epikardiyal yağ dokusu, miyokardiyal fibrozis

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